Angiogenic factors: role in esophageal cancer, a brief review

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Arquivos
art_LADEIRA_Angiogenic_factors_role_in_esophageal_cancer_a_brief_2018.PDF (693.25 KB)
Citações na Scopus
17
Tipo de produção
article
Data de publicação
2018
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
SPRINGER JAPAN KK
Autores
LADEIRA, Katia
MACEDO, Filipa
MARTINS, Sandra F.
Citação
ESOPHAGUS, v.15, n.2, p.53-58, 2018
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Esophageal cancer has an aggressive behavior with rapid tumor mass growth and frequently poor prognosis; it is known as one of the most fatal types of cancer worldwide. The identification of potential molecular markers that can predict the response to treatment and the prognosis of this cancer has been subject of a vast investigation in the recent years. Among several molecules, various angiogenic factors that are linked to the tumor development, growth, and invasion, such as VEGF, HGF, angiopoietin-2, IL-6, and TGF-B1, were investigated. In this paper, the authors sought to review the role of these angiogenic factors in prognosis and hypothesize how they can be used as a treatment target.
Palavras-chave
Esophageal cancer, HGF, Angiopoietin-2, IL-6, VEGF, TGF-B1
URI
https://observatorio.fm.usp.br/handle/OPI/26586
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Coleções
Artigos e Materiais de Revistas Científicas - IMT
Artigos e Materiais de Revistas Científicas - LIM/14
Artigos e Materiais de Revistas Científicas - ODS/03