ON-PUMP VERSUS OFF-PUMP CORONARY ARTERY BYPASS SURGERY IN PATIENTS WITH ADVANCED AGE: FIVE-YEAR FOLLOW-UP OF MASS III TRIAL

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorMELO, Rodrigo M. V.
dc.contributor.authorHUEB, Whady
dc.contributor.authorOIKAWA, Fernando T. C.
dc.contributor.authorCOSTA, Leandro
dc.contributor.authorSERRANO, Carlos
dc.contributor.authorGARZILLO, Cibele
dc.contributor.authorREZENDE, Paulo
dc.contributor.authorLIMA, Eduardo
dc.contributor.authorFAVARATO, Desiderio
dc.contributor.authorHUEB, Alexandre
dc.contributor.authorRAMIRES, Jose
dc.contributor.authorKALIL-FILHO, Roberto
dc.date.accessioned2013-10-11T21:17:37Z
dc.date.available2013-10-11T21:17:37Z
dc.date.issued2013
dc.description.abstractBackground: Advanced age is associated with increased mortality and morbidity in patients undergoing coronary artery bypass grafting (CABG), which may be a consequence of cardiopulmonary bypass. We aim to evaluate cardiac events and long-term clinical outcome in patients with advanced age and stable coronary artery disease (CAD) undergoing off-pump (OPCAB) and on-pump (ONCAB) CABG. Methods: The MASS III was a single-center randomized trial that evaluate 308 patients with stable CAD and preserved ventricular function assigned for: 155 to off-pump and 153 to on-pump CABG. Of this, 176 (58.3%) patients had 60 years or older at the time of randomization (90 of-pump and 86 on-pump). Primary composite end points were death, myocardial infarction, further revascularization, or stroke. Results: The two randomized groups were well-matched for baseline demographic, clinical, and angiographic characteristics. The mean age was 67.2 (±5.0) years. In hospital analysis ONCAB patients had a higher incidence of postoperative stroke or myocardial infarction: 13 (15.1%) vs 5 (5.6%); p=0.036. After 5-year follow-up, there were no significant differences between both strategies of CABG in the composite end points 29.1% vs 27.8%; (Hazard Ratio 1.07; CI 0.62 – 1.87; p=0.8) for ONCAB and OPCAB respectively. Conclusion: In this advanced age population, off-pump surgery did not add benefit in clinical outcome at 5-year follow-up.
dc.description.conferencedateMAR 09-11, 2013
dc.description.conferencelocalSan Francisco - CA, EUA
dc.description.conferencename62nd Annual Scientific Session of the American-College-of-Cardiology
dc.description.indexMEDLINE
dc.identifier.citationJOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, v.61, n.10, suppl.S, p.E1218-E1218, 2013
dc.identifier.issn0735-1097
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/2754
dc.language.isoeng
dc.publisherELSEVIER SCIENCE INC
dc.relation.ispartofJournal of the American College of Cardiology
dc.rightsrestrictedAccess
dc.rights.holderCopyright ELSEVIER SCIENCE INC
dc.subject.wosCardiac & Cardiovascular Systems
dc.titleON-PUMP VERSUS OFF-PUMP CORONARY ARTERY BYPASS SURGERY IN PATIENTS WITH ADVANCED AGE: FIVE-YEAR FOLLOW-UP OF MASS III TRIAL
dc.typeconferenceObject
dc.type.categorymeeting abstract
dc.type.versionpublishedVersion
dspace.entity.typePublication
hcfmusp.contributor.author-fmusphcRODRIGO MOREL VIEIRA DE MELO
hcfmusp.contributor.author-fmusphcWHADY ARMINDO HUEB
hcfmusp.contributor.author-fmusphcFERNANDO TEIICHI COSTA OIKAWA
hcfmusp.contributor.author-fmusphcLEANDRO MENEZES ALVES DA COSTA
hcfmusp.contributor.author-fmusphcCARLOS VICENTE SERRANO JUNIOR
hcfmusp.contributor.author-fmusphcCIBELE LARROSA GARZILLO
hcfmusp.contributor.author-fmusphcPAULO CURY REZENDE
hcfmusp.contributor.author-fmusphcEDUARDO GOMES LIMA
hcfmusp.contributor.author-fmusphcDESIDERIO FAVARATO
hcfmusp.contributor.author-fmusphcALEXANDRE CIAPPINA HUEB
hcfmusp.contributor.author-fmusphcJOSE ANTONIO FRANCHINI RAMIRES
hcfmusp.contributor.author-fmusphcROBERTO KALIL FILHO
hcfmusp.description.beginpageE1218
hcfmusp.description.endpageE1218
hcfmusp.description.issue10
hcfmusp.description.issuesuppl S
hcfmusp.description.volume61
hcfmusp.origemWOS
hcfmusp.origem.wosWOS:000316555201323
hcfmusp.publisher.cityNEW YORK
hcfmusp.publisher.countryUSA
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Arquivos
Coleções
Comunicações em Eventos - FM/MCP
Comunicações em Eventos - HC/ICESP
Comunicações em Eventos - HC/InCor
Comunicações em Eventos - LIM/11