Lifestyle in wine drinkers and abstemious: the relationship of coronary lesions, calcium score and risk factors
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Tipo de produção
conferenceObject
Data de publicação
2012
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Editora
LIPPINCOTT WILLIAMS & WILKINS
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Citação
CIRCULATION, v.125, n.19, p.E912-E912, 2012
Resumo
Introduction: Red wine (RW) protects the cardiovascular system but objective evidence based on coronary status is lacking. Objectives: To assess the effects of chronic RW consumption upon coronary lesion burden. Methods: We performed Coronary Computed Tomographic Angiography in 204 male subjects whose mean age was 58.95±7.3 years and related lesions to risk factors (RF). One hundred were chronic RW drinkers who consumed at least one glass of RW wine/day, 4 –5 times/week, in the last 5 years and 104 were abstemious. Results: RW drinkers consumed 25.78 gr alcohol/day vs 0 among abstemious; they also ingested more calories (2118.50kcal vs 1776.21kcal daily; p<0.01) mainly from saturated fats (22.98 g vs16.51g; p<0.05) than abstemious. Abstemious, however, ingested more fibers (22.73 gr vs17.49 gr; p<0.05). There were no significant differences regarding age, smoking, BMI, arterial hypertension, diabetes, LDL and triglycerides. Psychological factors including anxiety, depression and stress also were similar. However, plasma glucose was lower (97.5±18.3 mg% vs105.9±32.0 mg %; p<0.06) and HDL was higher (46.9±10.9 mg% vs 39.5±9.0 mg%;p<0.01) in RW drinkers compared to abstemious. Calcium score was higher on RW drinkers than in abstemious(144.43±362.2 vs 122.05±370.26; p<0.004). Lesions were classified as absent or 50%. Considering LM, ADA, RCA and Cx in proximal, median and distal portions, plus 3 marginal, 3 diagonal and 2 terminal RCA branches, 3672 segments were included in the analysis. There were no significant differences regarding lesions severity between groups, except for more frequent zero lesions in proximal Cx (86.3 x 71.4 %; p<0.016). Conclusion: Despite higher caloric intake and saturated fats, RW drinkers have similar coronary lesion burden; calcium score, however, was higher compared to abstemious. Higher HDL cholesterol as cribed to RW drinking and lower plasma glucose may have protective roles.
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Referências
- Coimbra SR, 2005, BRAZ J MED BIOL RES, V38, P1339, DOI 10.1590/S0100-879X2005000900008
- da Luz PL, 2004, BRAZ J MED BIOL RES, V37, P1275, DOI 10.1590/S0100-879X2004000900001