Antimicrobial peptides in the gut-brain axis: A straightforward review to unravel some missing links

dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorSILVA, Fabiano Pinheiro da
dc.contributor.authorBRUZAFERRO, Ewerton Vinicius Macarini
dc.contributor.authorCAMARA, Niels Olsen Saraiva
dc.date.accessioned2020-12-16T14:58:09Z
dc.date.available2020-12-16T14:58:09Z
dc.date.issued2020
dc.description.abstractAntimicrobial peptides (AMPs) are intriguing molecules, able to directly kill several microorganisms and to regulate multiple aspects of the immune response. Despite the extensive studies on the role of AMPs in the epithelial barrier, placing them as a pivotal line of defense against pathogen invasion, little attention has been directed to their role in the maintenance and modulation of the gut microbiota and, by consequence, of the homeostasis of extra intestinal tissues. Here, we review the recent literature about the microbiome-gut-brain axis, focusing on the role of AMPs in this scenario. We provide a straightforward revision of current data in order to provide an overview of the subject, discussing more in depth some points that, in our opinion, are crucial and have received little attention.eng
dc.description.indexMEDLINEeng
dc.description.sponsorshipConselho Nacional de Desenvolvimento Cientifico e TecnologicoNational Council for Scientific and Technological Development (CNPq)
dc.description.sponsorshipFundacao de Amparo a Pesquisa do Estado de Sao PauloFundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP)
dc.description.sponsorshipCoordenacao de Aperfeicoamento de Pessoal de Nivel SuperiorCAPES
dc.identifier.citationJOURNAL OF NEUROSCIENCE RESEARCH, v.98, n.12, p.2384-2389, 2020
dc.identifier.doi10.1002/jnr.24729
dc.identifier.eissn1097-4547
dc.identifier.issn0360-4012
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/38551
dc.language.isoeng
dc.publisherWILEYeng
dc.relation.ispartofJournal of Neuroscience Research
dc.rightsrestrictedAccesseng
dc.rights.holderCopyright WILEYeng
dc.subjectantimicrobial peptideseng
dc.subjectbraineng
dc.subjectguteng
dc.subjectinflammationeng
dc.subjectinnate immunityeng
dc.subjectmicrobiomeeng
dc.subject.othermicrobiomeeng
dc.subject.othercathelicidineng
dc.subject.otherll-37eng
dc.subject.othermechanismseng
dc.subject.otherpathologyeng
dc.subject.othersepsiseng
dc.subject.wosNeuroscienceseng
dc.titleAntimicrobial peptides in the gut-brain axis: A straightforward review to unravel some missing linkseng
dc.typearticleeng
dc.type.categoryrevieweng
dc.type.versionpublishedVersioneng
dspace.entity.typePublication
hcfmusp.author.externalCAMARA, Niels Olsen Saraiva:Univ Sao Paulo, Lab Imunobiol Transplantes, Dept Imunol, Inst Ciencias Biol, Sao Paulo, Brazil
hcfmusp.citation.scopus0
hcfmusp.contributor.author-fmusphcFABIANO PINHEIRO DA SILVA
hcfmusp.contributor.author-fmusphcEWERTON VINICIUS MACARINI BRUZAFERRO
hcfmusp.description.beginpage2384
hcfmusp.description.endpage2389
hcfmusp.description.issue12
hcfmusp.description.volume98
hcfmusp.origemWOS
hcfmusp.origem.pubmed32945561
hcfmusp.origem.scopus2-s2.0-85091000846
hcfmusp.origem.wosWOS:000570209600001
hcfmusp.publisher.cityHOBOKENeng
hcfmusp.publisher.countryUSAeng
hcfmusp.relation.referenceAl-Obaidi MMJ, 2018, CELL MOL NEUROBIOL, V38, P1349, DOI 10.1007/s10571-018-0609-2eng
hcfmusp.relation.referenceBrowne HP, 2017, NAT REV MICROBIOL, V15, P531, DOI 10.1038/nrmicro.2017.50eng
hcfmusp.relation.referenceMachado MCC, 2016, CURR PHARM DESIGN, V22, P4645, DOI 10.2174/1381612822666160510125331eng
hcfmusp.relation.referenceChen FD, 2019, CURR OPIN IMMUNOL, V56, P107, DOI 10.1016/j.coi.2018.12.003eng
hcfmusp.relation.referenceCheng HY, 2019, FRONT IMMUNOL, V10, DOI 10.3389/fimmu.2019.00607eng
hcfmusp.relation.referenceCHRISTENSEN DP, 1992, APPL ENVIRON MICROB, V58, P3312, DOI 10.1128/AEM.58.10.3312-3315.1992eng
hcfmusp.relation.referenceda Silva FP, 2017, IMMUNOL LETT, V182, P57, DOI 10.1016/j.imlet.2017.01.004eng
hcfmusp.relation.referenceda Silva FP, 2013, TISSUE CELL, V45, P318, DOI 10.1016/j.tice.2013.04.003eng
hcfmusp.relation.referenceda Silva FP, 2013, PEPTIDES, V44, P135, DOI 10.1016/j.peptides.2013.03.029eng
hcfmusp.relation.referenceda Silva FP, 2012, PEPTIDES, V36, P308, DOI 10.1016/j.peptides.2012.05.014eng
hcfmusp.relation.referenceda Silva FP, 2009, IMMUNOL CELL BIOL, V87, P496, DOI 10.1038/icb.2009.19eng
hcfmusp.relation.referencede la Fuente-Nunez C, 2018, ACS CHEM NEUROSCI, V9, P141, DOI 10.1021/acschemneuro.7b00373eng
hcfmusp.relation.referencede Paula VS, 2018, MOLECULES, V23, DOI 10.3390/molecules23082040eng
hcfmusp.relation.referenceDicks LMT, 2018, FRONT MICROBIOL, V9, DOI 10.3389/fmicb.2018.02297eng
hcfmusp.relation.referenceDickson RP, 2016, LANCET RESP MED, V4, P59, DOI 10.1016/S2213-2600(15)00427-0eng
hcfmusp.relation.referenceFabisiak A, 2016, PHARMACOL REP, V68, P802, DOI 10.1016/j.pharep.2016.03.015eng
hcfmusp.relation.referenceFulling C, 2019, NEURON, V101, P998, DOI 10.1016/j.neuron.2019.02.008eng
hcfmusp.relation.referenceGarcia-Gutierrez E, 2019, GUT MICROBES, V10, P1, DOI 10.1080/19490976.2018.1455790eng
hcfmusp.relation.referenceGerard P, 2016, CELL MOL LIFE SCI, V73, P147, DOI 10.1007/s00018-015-2061-5eng
hcfmusp.relation.referenceHamasaki MY, 2019, INFLAMMATION, V42, P1023, DOI 10.1007/s10753-019-00964-9eng
hcfmusp.relation.referenceHaney EF, 2019, FRONT CHEM, V7, DOI 10.3389/fchem.2019.00043eng
hcfmusp.relation.referenceIacob S, 2019, FRONT MICROBIOL, V9, DOI 10.3389/fmicb.2018.03328eng
hcfmusp.relation.referenceJiang WY, 2013, PEPTIDES, V50, P129, DOI 10.1016/j.peptides.2013.10.008eng
hcfmusp.relation.referenceKhlevner J, 2018, GASTROENTEROL CLIN N, V47, P727, DOI 10.1016/j.gtc.2018.07.002eng
hcfmusp.relation.referenceKnip M, 2016, NAT REV ENDOCRINOL, V12, P154, DOI 10.1038/nrendo.2015.218eng
hcfmusp.relation.referenceKowalski K, 2019, J NEUROGASTROENTEROL, V25, P48, DOI 10.5056/jnm18087eng
hcfmusp.relation.referenceKumariya R, 2019, MICROB PATHOGENESIS, V128, P171, DOI 10.1016/j.micpath.2019.01.002eng
hcfmusp.relation.referenceMcDonald D, 2016, MSPHERE, V1, DOI 10.1128/mSphere.00199-16eng
hcfmusp.relation.referenceMergaert P, 2018, NAT PROD REP, V35, P336, DOI 10.1039/c7np00056aeng
hcfmusp.relation.referenceMorizane S, 2012, J INVEST DERMATOL, V132, P135, DOI 10.1038/jid.2011.259eng
hcfmusp.relation.referenceMukhtar K, 2019, WORLD J GASTROENTERO, V25, P552, DOI 10.3748/wjg.v25.i5.552eng
hcfmusp.relation.referenceMunoz M, 2016, J CANCER, V7, P2341, DOI 10.7150/jca.16947eng
hcfmusp.relation.referenceNizet V, 2001, NATURE, V414, P454, DOI 10.1038/35106587eng
hcfmusp.relation.referenceNylen F, 2014, INNATE IMMUN-LONDON, V20, P364, DOI 10.1177/1753425913493338eng
hcfmusp.relation.referenceOami T, 2019, CURR OPIN CRIT CARE, V25, P145, DOI 10.1097/MCC.0000000000000582eng
hcfmusp.relation.referenceSchmidt TSB, 2018, CELL, V172, P1198, DOI 10.1016/j.cell.2018.02.044eng
hcfmusp.relation.referenceSchwabe RF, 2013, NAT REV CANCER, V13, P800, DOI [10.1002/path.5047, 10.1038/nrc3610]eng
hcfmusp.relation.referenceSeverance Emily G, 2020, Curr Top Behav Neurosci, V44, P67, DOI 10.1007/7854_2018_84eng
hcfmusp.relation.referenceSeverino P, 2017, J MOL MED, V95, P995, DOI 10.1007/s00109-017-1555-zeng
hcfmusp.relation.referenceShahnawaz M, 2012, J BIOL CHEM, V287, P11665, DOI 10.1074/jbc.M111.282533eng
hcfmusp.relation.referenceSkoniecznaZydecka K., 2018, J CLIN MED, V7, P12eng
hcfmusp.relation.referenceSrikantha P, 2019, INT J MOL SCI, V20, DOI 10.3390/ijms20092115eng
hcfmusp.relation.referenceThursby E, 2017, BIOCHEM J, V474, P1823, DOI 10.1042/BCJ20160510eng
hcfmusp.relation.referenceTropini C, 2017, CELL HOST MICROBE, V21, P433, DOI 10.1016/j.chom.2017.03.010eng
hcfmusp.relation.referenceVandamme D, 2012, CELL IMMUNOL, V280, P22, DOI 10.1016/j.cellimm.2012.11.009eng
hcfmusp.relation.referenceVasilchenko AS, 2019, ARCH MICROBIOL, V201, P147, DOI 10.1007/s00203-018-1610-3eng
hcfmusp.relation.referenceVerjans ET, 2016, PEPTIDES, V85, P16, DOI 10.1016/j.peptides.2016.09.002eng
hcfmusp.relation.referenceVieira ELM, 2012, J NUTR BIOCHEM, V23, P430, DOI 10.1016/j.jnutbio.2011.01.007eng
hcfmusp.relation.referenceWang Guangshun, 2012, Curr Biotechnol, V1, P72eng
hcfmusp.relation.referenceWang YL, 2018, FRONT IMMUNOL, V9, DOI 10.3389/fimmu.2018.02325eng
hcfmusp.relation.referenceWeiss GA, 2017, CELL MOL LIFE SCI, V74, P2959, DOI 10.1007/s00018-017-2509-xeng
hcfmusp.relation.referenceWlodarska M, 2015, CELL HOST MICROBE, V17, P577, DOI 10.1016/j.chom.2015.04.008eng
hcfmusp.relation.referenceXhindoli D, 2014, BIOCHEM J, V457, P263, DOI 10.1042/BJ20131048eng
hcfmusp.scopus.lastupdate2024-05-10
relation.isAuthorOfPublicationedaef269-8f62-4c6f-bf7b-bca6691d6c14
relation.isAuthorOfPublicationa0f27305-fcf6-4196-9dbb-f0ed0334c56b
relation.isAuthorOfPublication.latestForDiscoveryedaef269-8f62-4c6f-bf7b-bca6691d6c14
Arquivos
Pacote Original
Agora exibindo 1 - 1 de 1
Nenhuma Miniatura disponível
Nome:
art_SILVA_Antimicrobial_peptides_in_the_gutbrain_axis_A_straightforward_2020.PDF.pdf
Tamanho:
352.22 KB
Formato:
Adobe Portable Document Format
Descrição:
publishedVersion (English)