Delayed postoperative radiation therapy in local control of squamous cell carcinoma of the tongue and floor of the mouth

dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorAMAR, Ali
dc.contributor.authorCHEDID, Helma Maria
dc.contributor.authorCURIONI, Otávio Alberto
dc.contributor.authorDEDIVITIS, Rogério Aparecido
dc.contributor.authorRAPOPORT, Abrão
dc.contributor.authorCERNEA, Claudio Roberto
dc.contributor.authorBRANDÃO, Lenine Garcia
dc.date.accessioned2015-09-11T17:47:18Z
dc.date.available2015-09-11T17:47:18Z
dc.date.issued2014
dc.description.abstractObjective To evaluate the effect of time between surgery and postoperative radiation therapy on local recurrence of squamous cell carcinoma of the tongue and floor of the mouth. Methods A total of 154 patients treated between 1996 and 2007 were selected considering local recurrence rate and time of the adjuvant radiotherapy. Results Local recurrence was diagnosed in 54 (35%) patients. Radiation therapy reduced the rate of local recurrences, although with no statistical significance. The time between surgery and initiation of postoperative radiotherapy did not significantly influence the risk of local recurrence in patients referred to adjuvant treatment (p=0.49). Conclusion In the presence of risk factors for local recurrence, a short delay in starting the adjuvant radiation therapy does not contraindicate its performance.
dc.description.abstractObjetivo Avaliar o efeito do tempo entre o tratamento cirúrgico e a radioterapia pós-operatória nas recidivas locais do carcinoma epidermoide de língua e soalho da boca. Métodos Foram selecionados 154 pacientes tratados entre 1996 e 2007, considerando a frequência das recidivas locais e o tempo para início da radioterapia adjuvante. Resultados As recidivas locais foram diagnosticadas em 54 (35%) pacientes. A radioterapia reduziu a frequência de recidivas locais, embora sem significância estatística. O tempo entre a cirurgia e o início da radioterapia pós-operatória não influenciaram, de forma significante, no risco de recidivas locais entre o pacientes que tinham indicação de tratamento adjuvante (p=0,49). Conclusão Na presença de fatores de risco para recidiva local, um pequeno atraso no início da radioterapia adjuvante não contra-indica sua realização.
dc.description.indexMEDLINE
dc.identifier.citationEINSTEIN (SãO PAULO), v.12, n.4, p.477-479, 2014
dc.identifier.doi10.1590/S1679-45082014AO3006
dc.identifier.issn1679-4508
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/10525
dc.language.isoeng
dc.publisherInstituto Israelita de Ensino e Pesquisa Albert Einstein
dc.relation.ispartofEinstein (São Paulo)
dc.rightsopenAccess
dc.rights.holderCopyright Instituto Israelita de Ensino e Pesquisa Albert Einstein
dc.subjectCarcinoma, squamous cell/radiotherapy
dc.subjectTongue neoplasms/radiotherapy
dc.subjectMouth neoplasms/radiotherapy
dc.subjectTime factors
dc.subjectRecurrence
dc.subjectNeoplasias de células escamosas/radioterapia
dc.subjectNeoplasias da língua/radioterapia
dc.subjectNeoplasias bucais/radioterapia
dc.subjectFatores de tempo
dc.subjectRecidiva
dc.subject.wosMedicine, General & Internal
dc.titleDelayed postoperative radiation therapy in local control of squamous cell carcinoma of the tongue and floor of the mouth
dc.title.alternativeRetardo da radioterapia pós-operatória no controle local do carcinoma epidermoide de língua e soalho de boca
dc.typearticle
dc.type.categoryoriginal article
dc.type.versionpublishedVersion
dspace.entity.typePublication
hcfmusp.author.externalAMAR, Ali:Hospital Heliópolis, Brazil
hcfmusp.author.externalCHEDID, Helma Maria:Hospital Heliópolis, Brazil
hcfmusp.author.externalCURIONI, Otávio Alberto:Hospital Heliópolis, Brazil
hcfmusp.author.externalRAPOPORT, Abrão:Hospital Heliópolis, Brazil
hcfmusp.citation.scopus5
hcfmusp.contributor.author-fmusphcROGERIO APARECIDO DEDIVITIS
hcfmusp.contributor.author-fmusphcCLAUDIO ROBERTO CERNEA
hcfmusp.contributor.author-fmusphcLENINE GARCIA BRANDAO
hcfmusp.description.beginpage477
hcfmusp.description.endpage479
hcfmusp.description.issue4
hcfmusp.description.volume12
hcfmusp.origemsciELO
hcfmusp.origem.pubmed25628200
hcfmusp.origem.scieloSCIELO:S1679-45082014000400477
hcfmusp.origem.scopus2-s2.0-84929048059
hcfmusp.publisher.citySão Paulo
hcfmusp.publisher.countryBRAZIL
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hcfmusp.scopus.lastupdate2024-05-10
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