The health burden of pollution: the impact of prenatal exposure to air pollutants

dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorVIEIRA, Sandra E.
dc.date.accessioned2015-10-26T16:31:16Z
dc.date.available2015-10-26T16:31:16Z
dc.date.issued2015
dc.description.abstractExposure to atmospheric pollutants in both open and closed environments is a major cause of morbidity and mortality that may be both controlled and minimized. Despite growing evidence, several controversies and disagreements exist among the studies that have analyzed the effects of prenatal pollutant exposure. This review article aims to analyze primary scientific evidence of the effects of air pollution during pregnancy and the impact of these effects on the fetus, infant health, and in particular, the respiratory system. We performed a review of articles from the PubMed and Web of Science databases that were published in English within the past 5 years, particularly those related to birth cohorts that began in pregnancy with follow-up until the first years of life. The largest reported effects are associated with prenatal exposure to particulate matter, nitrogen dioxide, and tobacco smoke. The primary effects affect birth weight and other parameters of fetal biometry. There is strong evidence regarding the impact of pollutants on morbidity secondary to respiratory problems. Growing evidence links maternal smoking to childhood asthma and wheezing. The role of passive maternal smoking is less clear. Great heterogeneity exists among studies. There is a need for additional studies on birth cohorts to monitor the relationship between the exposure of pregnant women to pollutants and their children's progress during the first years of life.
dc.description.indexMEDLINE
dc.identifier.citationINTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, v.10, p.1111-1121, 2015
dc.identifier.doi10.2147/COPD.S40214
dc.identifier.issn1178-2005
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/11746
dc.language.isoeng
dc.publisherDOVE MEDICAL PRESS LTD
dc.relation.ispartofInternational Journal of Chronic Obstructive Pulmonary Disease
dc.rightsopenAccess
dc.rights.holderCopyright DOVE MEDICAL PRESS LTD
dc.subjectair pollutants
dc.subjectpregnancy
dc.subjectbirth weight
dc.subjectlung disease
dc.subjecttobacco
dc.subjectfetal development
dc.subject.otherprospective birth cohort
dc.subject.otherfine particulate matter
dc.subject.otherpolycyclic aromatic-hydrocarbons
dc.subject.otherventilatory lung-function
dc.subject.othercigarette-smoke exposure
dc.subject.otherfetal-growth
dc.subject.otherpregnancy outcomes
dc.subject.othermaternal exposure
dc.subject.otherintrauterine exposure
dc.subject.otherpreschool-children
dc.subject.wosRespiratory System
dc.titleThe health burden of pollution: the impact of prenatal exposure to air pollutants
dc.typearticle
dc.type.categoryreview
dc.type.versionpublishedVersion
dspace.entity.typePublication
hcfmusp.citation.scopus53
hcfmusp.contributor.author-fmusphcSANDRA ELISABETE VIEIRA
hcfmusp.description.beginpage1111
hcfmusp.description.endpage1121
hcfmusp.description.volume10
hcfmusp.origemWOS
hcfmusp.origem.pubmed26089661
hcfmusp.origem.scopus2-s2.0-84933502460
hcfmusp.origem.wosWOS:000355954100001
hcfmusp.publisher.cityALBANY
hcfmusp.publisher.countryNEW ZEALAND
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