Cognitive-behavioral rehabilitation vs. treatment as usual for bipolar patients: study protocol for a randomized controlled trial

Imagem de Miniatura
Arquivos
art_GOMES_Cognitivebehavioral_rehabilitation_vs_treatment_as_usual_for_bipolar_2017.PDF (487.77 KB)
Citações na Scopus
10
Tipo de produção
article
Data de publicação
2017
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
BIOMED CENTRAL LTD
Autores
BELIZARIO, Gabriel Okawa
Citação
TRIALS, v.18, article ID 142, 7p, 2017
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Background: Bipolar disorder (BD) is commonly associated with cognitive and functional impairments even during remission periods, and although a growing number of studies have demonstrated the benefits of psychotherapy as an add-on to pharmacological treatment, its effectiveness appears to be less compelling in severe presentations of the disorder. New interventions have attempted to improve cognitive functioning in BD patients, but results have been mixed. Methods: The study consists of a clinical trial comparing a new structured group intervention, called ""CognitiveBehavioral Rehabilitation,""with treatment as usual (TAU) for bipolar patients. The new approach is a combination of cognitive behavioral strategies and cognitive remediation exercises, consisting of 12 weekly group sessions of 90 min each. To be included in the study, patients must be diagnosed with BD type I or II, aged 18-55 years, in full or partial remission, and have an IQ of at least 80. A comprehensive neuropsychological battery, followed by mood, social functioning, and quality of life assessments will occur in three moments: pre and post intervention and 12 months later. The primary outcome of the study is to compare the time, in weeks, that the first full mood episode appears in patients who participated in either group of the study. Secondary outcome will include improvement in cognitive functions. Discussion: This is the first controlled trial assessing the validity and effectiveness of the new ""Cognitive-Behavioral Rehabilitation""intervention in preventing new mood episodes and improving cognitive and functional impairments.
Palavras-chave
Bipolar disorder, Psychotherapy, Treatment as usual, TAU, Cognitive rehabilitation, Functional impairment, Cognitive functioning, Cognitive-Behavioral Rehabilitation
URI
https://observatorio.fm.usp.br/handle/OPI/20146
Referências
  1. American Psychiatric Association, 2000, DIAGN STAT MAN MENT
  2. Arts B, 2008, PSYCHOL MED, V38, P771, DOI 10.1017/S0033291707001675
  3. Baune BT, 2015, BIPOLAR DISORD, V17, P41, DOI 10.1111/bdi.12341
  4. Beck JS., 1997, TERAPIA COGNITIVA TE
  5. Bonnin CM, 2014, HARVARD REV PSYCHIAT, V22, P326, DOI 10.1097/HRP.0000000000000062
  6. Bortolato B, 2015, NEUROPSYCH DIS TREAT, V11, P3111, DOI 10.2147/NDT.S76700
  7. Bourne C, 2013, ACTA PSYCHIAT SCAND, V128, P149, DOI 10.1111/acps.12133
  8. Cacilhas AA, 2009, VALUE HEALTH, V12, P624, DOI 10.1111/j.1524-4733.2008.00481.x
  9. Clark L, 2004, EUR ARCH PSY CLIN N, V254, P61, DOI 10.1007/s00406-004-0460-y
  10. Colom F, 2009, BRIT J PSYCHIAT, V194, P260, DOI 10.1192/bjp.bp.107.040485
  11. Colom F, 2003, ARCH GEN PSYCHIAT, V60, P402, DOI 10.1001/archpsyc.60.4.402
  12. Colom F, 2010, ACTA NEUROPSYCHIATR, V22, P50, DOI 10.1111/j.1601-5215.2010.00450.x
  13. de Barros P.K., 2013, ACTA PSYCHIAT SCAND, V127, P153
  14. Deckersbach T, 2010, CNS NEUROSCI THER, V16, P298, DOI 10.1111/j.1755-5949.2009.00110.x
  15. Del Prette ZAP, 2009, INVENTARIO HABILIDAD
  16. Demant KM, 2015, PLOS ONE, V10, DOI 10.1371/journal.pone.0127955
  17. Demant KM, 2013, TRIALS, V14, DOI 10.1186/1745-6215-14-378
  18. Giglio LMF, 2009, J AFFECT DISORDERS, V118, P161, DOI 10.1016/j.jad.2009.01.018
  19. First MB, 2002, STRUCTURED CLIN INTE
  20. Fleck MPA, 2000, REV SAUDE PUBL, V34, P178, DOI 10.1590/S0034-89102000000200012
  21. Geddes JR, 2013, LANCET, V381, P1672, DOI 10.1016/S0140-6736(13)60857-0
  22. Gomar JJ, 2015, SCHIZOPHRENIA BULL, V41, P1387, DOI 10.1093/schbul/sbv059
  23. Gomes BC, 2011, PSYCHOTHER PSYCHOSOM, V80, P144, DOI 10.1159/000320738
  24. Kapczinski F, 2009, EXPERT REV NEUROTHER, V9, P957, DOI [10.1586/ern.09.31, 10.1586/ERN.09.31]
  25. Kerr N, 2003, J AFFECT DISORDERS, V73, P253, DOI 10.1016/S0165-0327(02)00008-3
  26. Lahera G, 2013, J AFFECT DISORDERS, V146, P132, DOI 10.1016/j.jad.2012.06.032
  27. Meyer TD, 2012, PSYCHOL MED, V42, P1429, DOI 10.1017/S0033291711002522
  28. Miklowitz DJ, 2008, AM J PSYCHIAT, V165, P1408, DOI 10.1176/appi.ajp.2008.08040488
  29. Nierenberg AA, 2009, CLIN TRIALS, V6, P637, DOI 10.1177/1740774509347399
  30. Reinares M, 2014, J AFFECT DISORDERS, V156, P46, DOI 10.1016/j.jad.2013.12.017
  31. Robinson LJ, 2006, BIPOLAR DISORD, V8, P103, DOI 10.1111/j.1399-5618.2006.00277.x
  32. RUSH AJ, 1978, AM J PSYCHOTHER, V32, P201
  33. Samalin L, 2016, BIPOLAR DISORD, V18, P164, DOI 10.1111/bdi.12376
  34. Scott J, 2006, BRIT J PSYCHIAT, V188, P313, DOI 10.1192/bjp.188.4.313
  35. Scott J, 2012, J AFFECT DISORDERS, V142, P72, DOI 10.1016/j.jad.2012.04.005
  36. Tohen M, 2009, BIPOLAR DISORD, V11, P453, DOI 10.1111/j.1399-5618.2009.00726.x
  37. Torrent C, 2013, AM J PSYCHIAT, V170, P852, DOI 10.1176/appi.ajp.2012.12070971
  38. von Diemen L, 2007, REV BRAS PSIQUIATR, V29, P153, DOI 10.1590/S1516-44462006005000020
  39. Wechsler D., 2014, ESCALA WECHSLER ABRE

Coleções
Artigos e Materiais de Revistas Científicas - FM/MPS
Artigos e Materiais de Revistas Científicas - HC/IPq
Artigos e Materiais de Revistas Científicas - LIM/21