Long-term survival after surgical treatment followed by adjuvant systemic therapy for primary duodenal melanoma

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art_SURJAN_Longterm_survival_after_surgical_treatment_followed_by_adjuvant_2020.PDF (1.09 MB)
Citações na Scopus
5
Tipo de produção
article
Data de publicação
2020
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
SPRINGER JAPAN KK
Autores
SILVEIRA, Sergio do Prado
SANTOS, Elizabeth Santana dos
MEIRELLES, Luciana Rodrigues de
Citação
CLINICAL JOURNAL OF GASTROENTEROLOGY, v.13, n.4, p.532-537, 2020
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Primary mucosal malignant melanomas of the gastrointestinal tract are rare tumors associated to poor prognosis. Primary duodenal involvement by pigmented lesions is even more uncommon, and only a few reports exist in the literature. We report the case of a patient with large primary duodenal melanoma that presented with upper intestinal obstruction and bleeding that was submitted to urgent pancreaticoduodenectomy followed by adjuvant systemic therapy with an oral alkylating agent (temozolomide) plus intravenous cisplatin. The patient presents no signs of recurrence 3 years after the surgery. We consider that radical surgical resection followed by systemic therapy is a safe and effective treatment strategy option for primary mucosal gastrointestinal melanomas.
Palavras-chave
Melanoma, Duodenal neoplasms, Pancreaticoduodenectomy
URI
https://observatorio.fm.usp.br/handle/OPI/37995
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Coleções
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - ODS/03