Anomalous origin of the coronary artery arising from the opposite sinus: prevalence and outcomes in patients undergoing coronary CTA

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorCHEEZUM, Michael K.
dc.contributor.authorGHOSHHAJRA, Brian
dc.contributor.authorBITTENCOURT, Marcio S.
dc.contributor.authorHULTEN, Edward A.
dc.contributor.authorBHATT, Ami
dc.contributor.authorMOUSAVI, Negareh
dc.contributor.authorSHAH, Nishant R.
dc.contributor.authorVALENTE, Anne Marie
dc.contributor.authorRYBICKI, Frank J.
dc.contributor.authorSTEIGNER, Michael
dc.contributor.authorHAINER, Jon
dc.contributor.authorMACGILLIVRAY, Thomas
dc.contributor.authorHOFFMANN, Udo
dc.contributor.authorABBARA, Suhny
dc.contributor.authorCARLI, Marcelo F. Di
dc.contributor.authorYEH, Doreen DeFaria
dc.contributor.authorLANDZBERG, Michael
dc.contributor.authorLIBERTHSON, Richard
dc.contributor.authorBLANKSTEIN, Ron
dc.date.accessioned2017-08-17T19:32:25Z
dc.date.available2017-08-17T19:32:25Z
dc.date.issued2017
dc.description.abstractAims The impact of coronary computed tomographic angiography (CTA) on management of anomalous origin of the coronary artery arising from the opposite sinus (ACAOS) remains uncertain. We examined the prevalence, anatomical characterization, and outcomes of ACAOS patients undergoing CTA. Methods and results Among 5991 patients referred for CTA at two tertiary hospitals between January 2004 and June 2014, we identified 103 patients (1.7% prevalence) with 110 ACAOS vessels. Mean age was 52 years (range 5-83, 63% male), with 55% previously known ACAOS and 45% discovered on CTA. ACAOS subtypes included: 39% interarterial (n = 40 anomalous right coronary artery, n = 3 anomalous left coronary artery), 38% retroaortic, 15% subpulmonic, 5% prepulmonic, and 2% other. ACAOS patients were assessed for symptoms, ischaemic test results, revascularization, all-cause or cardiovascular (CV) death, and myocardial infarction. CTAs were reviewed for ACAOS course, take-off height and angle, length and severity of proximal narrowing, intramural course, and obstructive coronary artery disease (CAD). In follow-up (median 5.8 years), there were 20 surgical revascularizations and 3 CV deaths. After adjusting for obstructive CAD (n = 21/103, 20%), variables associated with ACAOS revascularization included the following: CV symptoms, proximal vessel narrowing >= 50%, length of narrowing.5.4 mm, and an interarterial course. Conclusion The prevalence of ACAOS on CTA was 1.7%, including 45% of cases discovered incidentally. CTA provided excellent characterization of ACAOS features associated with coronary revascularization, including the length and severity of proximal vessel narrowing.
dc.description.indexMEDLINE
dc.description.sponsorshipNHLBI NIH HHS
dc.identifier.citationEUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING, v.18, n.2, p.224-235, 2017
dc.identifier.doi10.1093/ehjci/jev323
dc.identifier.eissn2047-2412
dc.identifier.issn2047-2404
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/21607
dc.language.isoeng
dc.publisherOXFORD UNIV PRESS
dc.relation.ispartofEuropean Heart Journal-Cardiovascular Imaging
dc.rightsrestrictedAccess
dc.rights.holderCopyright OXFORD UNIV PRESS
dc.subjectanomalous coronary artery
dc.subjectcoronary computed tomographic angiography
dc.subjectprognosis
dc.subjectrevascularization
dc.subjectsudden cardiac death
dc.subject.othercomputed-tomography angiography
dc.subject.othersudden cardiac death
dc.subject.otheraortic origin
dc.subject.otherinterarterial course
dc.subject.othersurgical repair
dc.subject.othercontralateral sinus
dc.subject.othervalsalva
dc.subject.otheradults
dc.subject.otherassociation
dc.subject.otherguidelines
dc.subject.wosCardiac & Cardiovascular Systems
dc.subject.wosRadiology, Nuclear Medicine & Medical Imaging
dc.titleAnomalous origin of the coronary artery arising from the opposite sinus: prevalence and outcomes in patients undergoing coronary CTA
dc.typearticle
dc.type.categoryoriginal article
dc.type.versionpublishedVersion
dspace.entity.typePublication
hcfmusp.affiliation.countryEstados Unidos
hcfmusp.affiliation.countryisous
hcfmusp.author.externalCHEEZUM, Michael K.:Harvard Med Sch, Brigham & Womens Hosp, Dept Radiol, Boston, MA 02115 USA; Harvard Med Sch, Brigham & Womens Hosp, Dept Med, Div Cardiovasc, 75 Francis St, Boston, MA 02115 USA
hcfmusp.author.externalGHOSHHAJRA, Brian:Harvard Med Sch, Massachusetts Gen Hosp, Dept Radiol, Boston, MA USA
hcfmusp.author.externalHULTEN, Edward A.:Harvard Med Sch, Brigham & Womens Hosp, Dept Radiol, Boston, MA 02115 USA; Harvard Med Sch, Brigham & Womens Hosp, Dept Med, Div Cardiovasc, 75 Francis St, Boston, MA 02115 USA; Walter Reed Natl Mil Med Ctr, Serv Cardiol, Div Med, Bethesda, MD USA; Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA
hcfmusp.author.externalBHATT, Ami:Harvard Med Sch, Massachusetts Gen Hosp, Div Cardiol, Dept Med, Boston, MA USA
hcfmusp.author.externalMOUSAVI, Negareh:Harvard Med Sch, Brigham & Womens Hosp, Dept Radiol, Boston, MA 02115 USA; Harvard Med Sch, Brigham & Womens Hosp, Dept Med, Div Cardiovasc, 75 Francis St, Boston, MA 02115 USA
hcfmusp.author.externalSHAH, Nishant R.:Harvard Med Sch, Brigham & Womens Hosp, Dept Radiol, Boston, MA 02115 USA
hcfmusp.author.externalVALENTE, Anne Marie:Harvard Med Sch, Brigham & Womens Hosp, Dept Med, Div Cardiovasc, 75 Francis St, Boston, MA 02115 USA; Boston Childrens Hosp, Dept Cardiol, Boston, MA USA
hcfmusp.author.externalRYBICKI, Frank J.:Harvard Med Sch, Brigham & Womens Hosp, Dept Radiol, Boston, MA 02115 USA
hcfmusp.author.externalSTEIGNER, Michael:Harvard Med Sch, Brigham & Womens Hosp, Dept Radiol, Boston, MA 02115 USA
hcfmusp.author.externalHAINER, Jon:Harvard Med Sch, Brigham & Womens Hosp, Dept Radiol, Boston, MA 02115 USA
hcfmusp.author.externalMACGILLIVRAY, Thomas:Harvard Med Sch, Massachusetts Gen Hosp, Dept Surg, Boston, MA USA
hcfmusp.author.externalHOFFMANN, Udo:Harvard Med Sch, Massachusetts Gen Hosp, Dept Radiol, Boston, MA USA
hcfmusp.author.externalABBARA, Suhny:Univ Texas Southwestern Med Ctr Dallas, Dept Radiol, Dallas, TX USA
hcfmusp.author.externalCARLI, Marcelo F. Di:Harvard Med Sch, Brigham & Womens Hosp, Dept Radiol, Boston, MA 02115 USA; Harvard Med Sch, Brigham & Womens Hosp, Dept Med, Div Cardiovasc, 75 Francis St, Boston, MA 02115 USA
hcfmusp.author.externalYEH, Doreen DeFaria:Harvard Med Sch, Massachusetts Gen Hosp, Div Cardiol, Dept Med, Boston, MA USA
hcfmusp.author.externalLANDZBERG, Michael:Harvard Med Sch, Brigham & Womens Hosp, Dept Med, Div Cardiovasc, 75 Francis St, Boston, MA 02115 USA; Boston Childrens Hosp, Dept Cardiol, Boston, MA USA
hcfmusp.author.externalLIBERTHSON, Richard:Harvard Med Sch, Massachusetts Gen Hosp, Div Cardiol, Dept Med, Boston, MA USA
hcfmusp.author.externalBLANKSTEIN, Ron:Harvard Med Sch, Brigham & Womens Hosp, Dept Radiol, Boston, MA 02115 USA; Harvard Med Sch, Brigham & Womens Hosp, Dept Med, Div Cardiovasc, 75 Francis St, Boston, MA 02115 USA
hcfmusp.citation.scopus74
hcfmusp.contributor.author-fmusphcMARCIO SOMMER BITTENCOURT
hcfmusp.description.beginpage224
hcfmusp.description.endpage235
hcfmusp.description.issue2
hcfmusp.description.volume18
hcfmusp.origemWOS
hcfmusp.origem.pubmed26848152
hcfmusp.origem.scopus2-s2.0-85015694197
hcfmusp.origem.wosWOS:000397270500017
hcfmusp.publisher.cityOXFORD
hcfmusp.publisher.countryENGLAND
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