Socket Reconstruction With Bleomycin, Gentamicin, and Gelatin Sponges Following Eyelid-Sparing Orbital Exenteration for a Colobomatous Macrocyst in an Infant

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorMICHELSON, Sarah J.
dc.contributor.authorCIONGOLI, Marina R.
dc.contributor.authorELNER, Victor M.
dc.contributor.authorKAHANA, Alon
dc.date.accessioned2019-01-17T13:39:10Z
dc.date.available2019-01-17T13:39:10Z
dc.date.issued2018
dc.description.abstractMicrophthalmia is defined by a globe axial length greater than or equal to 2 standard deviations below the age-adjusted mean and can occur as part of a broader syndrome. The presence of a colobomatous cyst with microphthalmia signifies failure of the embryonic neuroectodermal fissure to close appropriately during development of the globe, creating a protuberant globular appendage that inhibits normal growth and development of the eye itself. Cystic reaccumulation of fluid is common after aspiration or surgical removal. Here, the authors describe a case of a young boy with a colobomatous cyst who underwent eyelid-sparing orbital exenteration followed by reconstruction with absorbable gelatin sponge (Gelfoam, Pfizer, Inc.) and the chemotherapeutic agent bleomycin to promote scarring, achieving the equivalent of a biointegrated implant and facilitating satisfactory placement of an ocular prosthesis. A 2-year follow-up MRI revealed adequate volume in the posterior orbit.eng
dc.description.indexMEDLINEeng
dc.description.sponsorshipResearch to Prevent Blindness, Inc.
dc.identifier.citationOPHTHALMIC PLASTIC AND RECONSTRUCTIVE SURGERY, v.34, n.6, p.E201-E203, 2018
dc.identifier.doi10.1097/IOP.0000000000001246
dc.identifier.eissn1537-2677
dc.identifier.issn0740-9303
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/30165
dc.language.isoeng
dc.publisherLIPPINCOTT WILLIAMS & WILKINSeng
dc.relation.ispartofOphthalmic Plastic and Reconstructive Surgery
dc.rightsrestrictedAccesseng
dc.rights.holderCopyright LIPPINCOTT WILLIAMS & WILKINSeng
dc.subject.othercongenital microphthalmoseng
dc.subject.othermanagementeng
dc.subject.wosOphthalmologyeng
dc.subject.wosSurgeryeng
dc.titleSocket Reconstruction With Bleomycin, Gentamicin, and Gelatin Sponges Following Eyelid-Sparing Orbital Exenteration for a Colobomatous Macrocyst in an Infanteng
dc.typearticleeng
dc.type.categoryoriginal articleeng
dc.type.versionpublishedVersioneng
dspace.entity.typePublication
hcfmusp.affiliation.countryEstados Unidos
hcfmusp.affiliation.countryisous
hcfmusp.author.externalMICHELSON, Sarah J.:Univ Michigan, Kellogg Eye Ctr, Dept Ophthalmol & Visual Sci, 1000 Wall St, Ann Arbor, MI 48109 USA
hcfmusp.author.externalELNER, Victor M.:Univ Michigan, Kellogg Eye Ctr, Dept Ophthalmol & Visual Sci, 1000 Wall St, Ann Arbor, MI 48109 USA
hcfmusp.author.externalKAHANA, Alon:Univ Michigan, Kellogg Eye Ctr, Dept Ophthalmol & Visual Sci, 1000 Wall St, Ann Arbor, MI 48109 USA
hcfmusp.citation.scopus1
hcfmusp.contributor.author-fmusphcMARINA RAVAGNANI CIONGOLI
hcfmusp.description.beginpageE201
hcfmusp.description.endpageE203
hcfmusp.description.issue6
hcfmusp.description.volume34
hcfmusp.origemWOS
hcfmusp.origem.pubmed30320716
hcfmusp.origem.scopus2-s2.0-85056353464
hcfmusp.origem.wosWOS:000450435100010
hcfmusp.publisher.cityPHILADELPHIAeng
hcfmusp.publisher.countryUSAeng
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hcfmusp.scopus.lastupdate2024-05-10
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