PROGNOSTIC FACTORS FOR LEFT COLECTOMY FOR COLON CANCER: A TEN YEARS EXPERIENCE OF A SINGLE UNIVERSITY INSTITUTION

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorNAHAS, Sergio Carlos
dc.contributor.authorNAHAS, Caio Sergio
dc.contributor.authorBUSTAMANTE-LOPEZ, Leonardo Alfonso
dc.contributor.authorPINTO, Rodrigo Ambar
dc.contributor.authorMARQUES, Carlos Frederico Sparapan
dc.contributor.authorCAMPOS, Fabio Guilherme
dc.contributor.authorCECCONELLO, Ivan
dc.date.accessioned2017-10-31T14:43:41Z
dc.date.available2017-10-31T14:43:41Z
dc.date.issued2017
dc.description.abstractABSTRACT Background: Colorectal cancer is the third most common cancer in the world. In Brazil, it is the leading cause of cancer in the gastrointestinal tract. Aim: To evaluate the preoperative, perioperative, and postoperative risk factors for recurrence and overall survival of patients with left colon cancer operated during a ten-year period. Methods: Patients with left colon cancer surgically treated underwent clinical preoperative workout and cancer staging. The following factors were studied: gender, age, tumor location, T stage, lymph node yield, N stage, M stage, histological type, and tumor differentiation. It was analyzed the influence in five-year overall survival. Results: A total of 173 patients underwent left colectomy for colon cancer. There was a slight predominance of male gender with 50.9%. The mean age was 60.8 years old. Fifteen (8.7%) tumors were located at splenic flexure, 126 (72.8%) at sigmoid colon, and 32 (18.5%) at descending colon. The median length of hospital stay was seven days. Mean survival was 47.5 months. At 60 months seven patients (4%) lost follow-up, 38 patients (21.9%) deceased and 135 patients (78%) were alive. Overall survival time was 48 months. Conclusion: Advanced stages (T3-T4, N+ and M+) were the only factors associated with poor long term survival in left colon cancer.
dc.description.abstractRESUMO Racional: O câncer colorretal é o terceiro câncer mais comum no mundo. No Brasil é a principal causa no trato gastrointestinal. Objetivo: Avaliar os fatores de riscos pré, peri e pós-operatório para recorrência e sobrevida global de pacientes com câncer de cólon esquerdo operado durante um período de dez anos. Métodos: Os pacientes com câncer de cólon esquerdo operados foram retrospectivamente avaliados. Os seguintes fatores foram estudados: gênero, idade, localização do tumor, estádio T, número de linfonodos, estágio N, estágio M, tipo histológico e diferenciação tumoral. Foi analisada a influência desses fatores na sobrevida global de cinco anos. Resultados: 173 pacientes foram submetidos à colectomia para câncer de cólon esquerdo. O gênero masculino predominou com 50,9%. A média de idade foi de 60,8 anos. Quinze (8,7%) tumores foram localizados no ângulo esplênico, 126 (72,8%) no sigmóide e 32 (18,5%) e no descendente. A média do tempo de internação foi de sete dias. A sobrevida média foi de 47,5 meses. Aos 60 meses sete doentes (4%) perderam o seguimento, 38 (21,9%) faleceram e 135 (78%) estavam vivos. O tempo de sobrevida global foi de 48 meses. Conclusão: Os estádios avançados (T3-T4, N e M+) foram os únicos fatores associados à menor sobrevida em longo prazo em câncer de cólon esquerdo.
dc.description.indexMEDLINE
dc.identifier.citationABCD-ARQUIVOS BRASILEIROS DE CIRURGIA DIGESTIVA-BRAZILIAN ARCHIVES OF DIGESTIVE SURGERY, v.30, n.2, p.103-107, 2017
dc.identifier.doi10.1590/0102-6720201700020006
dc.identifier.eissn2317-6326
dc.identifier.issn0102-6720
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/22235
dc.language.isoeng
dc.publisherColégio Brasileiro de Cirurgia Digestiva
dc.relation.ispartofABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo)
dc.rightsopenAccess
dc.rights.holderCopyright Colégio Brasileiro de Cirurgia Digestiva
dc.subjectColonic neoplasms
dc.subjectLymph nodes
dc.subjectSurgical procedures
dc.subjectColorectal surgery
dc.subjectCirurgia colorretal
dc.subjectNeoplasias do cólon sigmoide
dc.subjectProcedimentos cirúrgicos
dc.subjectLinfonodos
dc.subject.otherCOLORECTAL-CANCER
dc.subject.otherLYMPH-NODES
dc.subject.otherSURVIVAL
dc.subject.otherMORTALITY
dc.subject.otherTIME
dc.titlePROGNOSTIC FACTORS FOR LEFT COLECTOMY FOR COLON CANCER: A TEN YEARS EXPERIENCE OF A SINGLE UNIVERSITY INSTITUTION
dc.title.alternativeFATORES PROGNÓSTICOS DA COLECTOMIA ESQUERDA PARA CÂNCER DE CÓLON: EXPERIÊNCIA DE DEZ ANOS DE UMA INSTITUIÇÃO UNIVERSITÁRIA
dc.typearticle
dc.type.categoryoriginal article
dc.type.versionpublishedVersion
dspace.entity.typePublication
hcfmusp.contributor.author-fmusphcSERGIO CARLOS NAHAS
hcfmusp.contributor.author-fmusphcCAIO SERGIO RIZKALLAH NAHAS
hcfmusp.contributor.author-fmusphcLEONARDO ALFONSO BUSTAMANTE LOPEZ
hcfmusp.contributor.author-fmusphcRODRIGO AMBAR PINTO
hcfmusp.contributor.author-fmusphcCARLOS FREDERICO SPARAPAN MARQUES
hcfmusp.contributor.author-fmusphcFABIO GUILHERME CASERTA MARYSSAEL DE CAMPOS
hcfmusp.contributor.author-fmusphcIVAN CECCONELLO
hcfmusp.description.beginpage103
hcfmusp.description.endpage107
hcfmusp.description.issue2
hcfmusp.description.volume30
hcfmusp.origemWOS
hcfmusp.origem.pubmed29257844
hcfmusp.origem.scieloSCIELO:S0102-67202017000200103
hcfmusp.origem.wosWOS:000416611600006
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