Noninvasive Techniques for Management of Erythema Multiforme

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorMARTINS, Fabiana
dc.contributor.authorPALLOS, Debora
dc.contributor.authorCANDEIA, Jodkandlys
dc.contributor.authorZERBINATI, Rodrigo
dc.contributor.authorBRAZ-SILVA, Paulo Henrique
dc.contributor.authorCAMPOS, Luana
dc.date.accessioned2024-02-15T15:01:10Z
dc.date.available2024-02-15T15:01:10Z
dc.date.issued2023
dc.description.abstractAn 18-year-old man was referred for a diagnosis of extensive oral lesions. During the interview, he reported a medical history of ganglionic tuberculosis, type 2 herpes infection, and significant weight loss due to dysphagia. Intraoral exam revealed multiple painful and ulcerated lesions covered by pseudomembrane. Lesions were observed on the labial and buccal mucosa, tongue, and soft palate. The laboratory findings included serum positivity for the Epstein-Barr virus, and salivary tests showed positive values for herpes simplex virus (HSV-2) and human herpesvirus (HHV-7). The diagnostic hypothesis was based on clinical findings and viral infection detected in the saliva, which triggered an immunological disorder, that is, erythema multiforme (EM). The treatment consisted of antimicrobial photodynamic therapy (aPDT), with substantial improvement in pain and healing as seen in the following twenty-four hours. Complete resolution of the lesions was achieved five days after the first session. Once the diagnosis of virus-induced EM was confirmed, noninvasive techniques (e.g., salivary tests and aPDT) were very successful and can be indicated for managing these lesions.eng
dc.description.indexPubMed
dc.description.indexWoS
dc.description.indexScopus
dc.description.sponsorshipFundao de Amparo Pesquisa do Estado de So Paulo [2018/02568-8, 2020/15533-8]
dc.description.sponsorshipFAPESP
dc.identifier.citationCASE REPORTS IN DENTISTRY, v.2023, article ID 9938939, 4p, 2023
dc.identifier.doi10.1155/2023/9938939
dc.identifier.eissn2090-6455
dc.identifier.issn2090-6447
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/58294
dc.language.isoeng
dc.publisherHINDAWI LTDeng
dc.relation.ispartofCase Reports in Dentistry
dc.rightsrestrictedAccesseng
dc.rights.holderCopyright HINDAWI LTDeng
dc.subject.otherlasereng
dc.subject.wosDentistry, Oral Surgery & Medicineeng
dc.titleNoninvasive Techniques for Management of Erythema Multiformeeng
dc.typearticleeng
dc.type.categoryoriginal articleeng
dc.type.versionpublishedVersioneng
dspace.entity.typePublication
hcfmusp.author.externalMARTINS, Fabiana:Univ Santo Amaro, Sch Dent, Postgrad Program Dent, Rua Prof Eneas Siqueira Neto,340 Jardim Imbuias, BR-04829300 Sao Paulo, SP, Brazil; Univ Sao Paulo, Sch Dent, Dept Stomatol, Ave Prof Lineu Prestes 2227, BR-05508000 Sao Paulo, SP, Brazil
hcfmusp.author.externalPALLOS, Debora:Univ Santo Amaro, Sch Dent, Postgrad Program Dent, Rua Prof Eneas Siqueira Neto,340 Jardim Imbuias, BR-04829300 Sao Paulo, SP, Brazil
hcfmusp.author.externalCANDEIA, Jodkandlys:Univ Santo Amaro, Sch Dent, Postgrad Program Dent, Rua Prof Eneas Siqueira Neto,340 Jardim Imbuias, BR-04829300 Sao Paulo, SP, Brazil
hcfmusp.author.externalCAMPOS, Luana:Univ Santo Amaro, Sch Dent, Postgrad Program Dent, Rua Prof Eneas Siqueira Neto,340 Jardim Imbuias, BR-04829300 Sao Paulo, SP, Brazil
hcfmusp.citation.scopus0
hcfmusp.contributor.author-fmusphcRODRIGO MELIM ZERBINATI
hcfmusp.contributor.author-fmusphcPAULO HENRIQUE BRAZ DA SILVA
hcfmusp.description.articlenumber9938939
hcfmusp.description.volume2023
hcfmusp.origemWOS
hcfmusp.origem.pubmed38149304
hcfmusp.origem.scopus2-s2.0-85181563556
hcfmusp.origem.wosWOS:001131908400001
hcfmusp.publisher.cityLONDONeng
hcfmusp.publisher.countryENGLANDeng
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hcfmusp.scopus.lastupdate2024-05-19
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