Post-Exercise Hypotension and Its Mechanisms Differ after Morning and Evening Exercise: A Randomized Crossover Study

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art_BRITO_PostExercise_Hypotension_and_Its_Mechanisms_Differ_after_Morning_2015.PDF (754.29 KB)
Citações na Scopus
57
Tipo de produção
article
Data de publicação
2015
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
PUBLIC LIBRARY SCIENCE
Autores
BRITO, Leandro C. de
SILVA JUNIOR, Natan D. da
TINUCCI, Tais
CASARINI, Dulce E.
CIPOLLA-NETO, Jose
FORJAZ, Claudia L. M.
Citação
PLOS ONE, v.10, n.7, article ID e0132458, 16p, 2015
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Post-exercise hypotension (PEH), calculated by the difference between post and pre-exercise values, it is greater after exercise performed in the evening than the morning. However, the hypotensive effect of morning exercise may be masked by the morning circadian increase in blood pressure. This study investigated PEH and its hemodynamic and autonomic mechanisms after sessions of aerobic exercise performed in the morning and evening, controlling for responses observed after control sessions performed at the same times of day. Sixteen pre-hypertensive men underwent four sessions (random order): two conducted in the morning (7:30am) and two in the evening (5pm). At each time of day, subjects underwent an exercise (cycling, 45 min, 50%VO(2)peak) and a control (sitting rest) session. Measurements were taken pre- and post-interventions in all the sessions. The net effects of exercise were calculated for each time of day by [(post-pre exercise)-(post-pre control)] and were compared by paired t-test (P<0.05). Exercise hypotensive net effects (e.g., decreasing systolic, diastolic and mean blood pressure) occurred at both times of day, but systolic blood pressure reductions were greater after morning exercise (-7 +/- 3 vs. -3 +/- 4 mmHg, P<0.05). Exercise decreased cardiac output only in the morning (-460 +/- 771 ml/min, P<0.05), while it decreased stroke volume similarly at both times of day and increased heart rate less in the morning than in the evening (+7 +/- 5 vs. +10 +/- 5 bpm, P<0.05). Only evening exercise increased sympathovagal balance (+1.5 +/- 1.6, P<0.05) and calf blood flow responses to reactive hyperemia (+120 +/- 179 vs. -70 +/- 188 U, P<0.05). In conclusion, PEH occurs after exercise conducted at both times of day, but the systolic hypotensive effect is greater after morning exercise when circadian variations are considered. This greater effect is accompanied by a reduction of cardiac output due to a smaller increase in heart rate and cardiac sympathovagal balance.
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URI
https://observatorio.fm.usp.br/handle/OPI/11843
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Coleções
Artigos e Materiais de Revistas Científicas - FM/Outros
Artigos e Materiais de Revistas Científicas - ODS/03