Humidification and mucus transport in critical patients: Clinical and therapeutic implications

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorNAKAGAWA, N. K.
dc.contributor.authorNASCIMENTO, J. A.
dc.contributor.authorNICOLA, M. L.
dc.contributor.authorSALDIVA, P. H. N.
dc.date.accessioned2023-02-09T19:57:22Z
dc.date.available2023-02-09T19:57:22Z
dc.date.issued2012
dc.description.abstractAn adult man inhales more than 12,000 l of air per day, which may contain particles and microorganisms. The epithelium of the conducting airways, from the nose to the bronchioli, are anatomically and physiologically designed to protect the alveoli by providing clean, warmed and fully saturated air at this level, where an efficient gas exchange must occur, and by providing specific defense mechanisms, such as trapping particles and microorganisms in the mucus and mucociliary transport of these agents in the direction of the oropharynx, where they will be swallowed or expectorated. Mucociliary transport (MCT) is an important respiratory defense mechanism, which efficiency depends on the equilibrium among three major components: ciliary beating, airway surface liquid (the periciliary liquid and mucus), and the interaction between cilia and mucus. In the intensive care unit (ICU) and emergency department, many factors can increase the risks of mucus transport dysfunction. Among them, artificial inspired air conditioning is a basic factor with physiological and clinical impact in critically ill patients. © Springer-Verlag Berlin Heidelberg 2012.
dc.identifier.citationNakagawa, N. K.; Nascimento, J. A.; Nicola, M. L.; Saldiva, P. H. N.. Humidification and mucus transport in critical patients: Clinical and therapeutic implications. In: . HUMIDIFICATION IN THE INTENSIVE CARE UNIT: THE ESSENTIALS: SPRINGER BERLIN HEIDELBERG, 2012. p.215-225.
dc.identifier.doi10.1007/978-3-642-02974-5_26
dc.identifier.isbn9783642029745; 9783642029738
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/51096
dc.language.isoeng
dc.publisherSPRINGER BERLIN HEIDELBERG
dc.relation.ispartofHUMIDIFICATION IN THE INTENSIVE CARE UNIT: THE ESSENTIALS
dc.rightsrestrictedAccess
dc.rights.holderCopyright SPRINGER BERLIN HEIDELBERG
dc.titleHumidification and mucus transport in critical patients: Clinical and therapeutic implications
dc.typebookPart
dc.type.categorybook chapter
dc.type.versionpublishedVersion
dspace.entity.typePublication
hcfmusp.citation.scopus0
hcfmusp.contributor.author-fmusphcNAOMI KONDO NAKAGAWA
hcfmusp.contributor.author-fmusphcJULIANA ARAUJO NASCIMENTO
hcfmusp.contributor.author-fmusphcMARINA LAZZARI NICOLA
hcfmusp.contributor.author-fmusphcPAULO HILARIO NASCIMENTO SALDIVA
hcfmusp.description.beginpage215
hcfmusp.description.endpage225
hcfmusp.origemSCOPUS
hcfmusp.origem.scopus2-s2.0-84956695470
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