Acute Disseminated Encephalomyelitis: Current Perspectives

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Arquivos
art_PAOLILO_Acute_Disseminated_Encephalomyelitis_Current_Perspectives_2020.PDF (1.1 MB)
Citações na Scopus
28
Tipo de produção
article
Data de publicação
2020
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
MDPI
Autores
DEIVA, Kumaran
NEUTEBOOM, Rinze
ROSTASY, Kevin
LIM, Ming
Citação
CHILDREN-BASEL, v.7, n.11, article ID 210, 15p, 2020
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Acute disseminated encephalomyelitis (ADEM) is an immune-mediated central nervous system (CNS) disorder, characterized by polyfocal symptoms, encephalopathy and typical magnetic resonance imaging (MRI) findings, that especially affects young children. Advances in understanding CNS neuroimmune disorders as well as the association of myelin oligodendrocyte glycoprotein antibody (MOG-Ab) with both monophasic and recurrent forms of ADEM have led to new insights into its definition, management and outcome. In this review, we aim to provide an update based on current epidemiologic, clinical, radiological and immunopathological aspects and clinical outcome of ADEM.
Palavras-chave
acute disseminated encephalomyelitis (ADEM), acquired demyelination syndrome (ADS), myelin oligodendrocyte glycoprotein antibody (MOG-Ab), multiple sclerosis (MS), optic neuritis (ON), neuromyelitis optica spectrum disorder (NMOSD)
URI
https://observatorio.fm.usp.br/handle/OPI/39409
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Coleções
Artigos e Materiais de Revistas Científicas - FM/Outros
Artigos e Materiais de Revistas Científicas - LIM/45