Essential data dimensions for prospective international data collection in older age bipolar disorder (OABD): Recommendations from the GAGE-BD group

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Citações na Scopus
2
Tipo de produção
article
Data de publicação
2023
DOI
Scopus
Web of Science
PubMed
Dimensions
Título da Revista
ISSN da Revista
Título do Volume
Editora
WILEY
Autores
LAVIN, Paola
REJ, Soham
OLAGUNJU, Andrew T.
TEIXEIRA, Antonio L.
DOLS, Annemieke
ALDA, Martin
ALMEIDA, Osvaldo P.
ALTINBAS, Kursat
BALANZA-MARTINEZ, Vicent
BARBOSA, Izabela G.
Citação
BIPOLAR DISORDERS, v.25, n.7, p.554-563, 2023
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
BackgroundBy 2030, over 50% of individuals living with bipolar disorder (BD) are expected to be aged >= 50 years. However, older age bipolar disorder (OABD) remains understudied. There are limited large-scale prospectively collected data organized in key dimensions capable of addressing several fundamental questions about BD affecting this subgroup of patients. MethodsWe developed initial recommendations for the essential dimensions for OABD data collection, based on (1) a systematic review of measures used in OABD studies, (2) a Delphi consensus of international OABD experts, (3) experience with harmonizing OABD data in the Global Aging & Geriatric Experiments in Bipolar Disorder Database (GAGE-BD, n >= 4500 participants), and (4) critical feedback from 34 global experts in geriatric mental health. ResultsWe identified 15 key dimensions and variables within each that are relevant for the investigation of OABD: (1) demographics, (2) core symptoms of depression and (3) mania, (4) cognition screening and subjective cognitive function, (5) elements for BD diagnosis, (6) descriptors of course of illness, (7) treatment, (8) suicidality, (9) current medication, (10) psychiatric comorbidity, (11) psychotic symptoms, (12) general medical comorbidities, (13) functioning, (14) family history, and (15) other. We also recommend particular instruments for capturing some of the dimensions and variables. ConclusionThe essential data dimensions we present should be of use to guide future international data collection in OABD and clinical practice. In the longer term, we aim to establish a prospective consortium using this core set of dimensions and associated variables to answer research questions relevant to OABD.
Palavras-chave
international collaboration, older age bipolar disorder, prospective studies
URI
https://observatorio.fm.usp.br/handle/OPI/58988
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Coleções
Artigos e Materiais de Revistas Científicas - FM/MPS