Fresh Osteochondral Allograft Transplantation for Fractures of the Knee

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorGRACITELLI, Guilherme C.
dc.contributor.authorTIRICO, Luis Eduardo Passarelli
dc.contributor.authorMCCAULEY, Julie C.
dc.contributor.authorPULIDO, Pamela A.
dc.contributor.authorBUGBEE, William D.
dc.date.accessioned2017-06-09T15:40:14Z
dc.date.available2017-06-09T15:40:14Z
dc.date.issued2017
dc.description.abstractObjective The purpose of this study was to evaluate functional outcomes and allograft survivorship among patients with knee fracture who underwent fresh osteochondral allograft (OCA) transplantation as a salvage treatment option. Design Retrospective analysis of prospectively collected data. Setting Department of Orthopaedic Surgery at one hospital. Patients Fresh OCAs were implanted for osteochondral lesions after knee fracture in 24 males and 15 females with an average age of 34 years. Twenty-nine lesions (74%) were tibial plateau fractures, 6 (15%) were femoral condyle fractures, and 4 (10%) were patella fractures. Main Outcome Measurements Clinical evaluation included modified Merle d'Aubigne-Postel (18-point), International Knee Documentation Committee, and Knee Society function scores, and patient satisfaction. Failure of OCA was defined as revision OCA or conversion to total knee arthroplasty (TKA). Results Nineteen of 39 knees (49%) had further surgery. Ten knees (26%) were considered OCA failures (3 OCA revisions, 6 TKA, and 1 patellectomy). Survivorship of the OCA was 82.6% at 5 years and 69.6% at 10 years. Among the 29 knees (74%) that had the OCA still in situ, median follow-up was 6.6 years. Pain and function improved from preoperative to latest follow-up; 83% of patients reported satisfaction with OCA results. Conclusion OCA transplantation is a useful salvage treatment option for osteochondral lesions caused by knee fracture. Although the reoperation rate was high, successful outcome was associated with significant clinical improvement.
dc.description.indexPubMed
dc.identifier.citationCARTILAGE, v.8, n.2, p.155-161, 2017
dc.identifier.doi10.1177/1947603516657640
dc.identifier.eissn1947-6043
dc.identifier.issn1947-6035
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/20337
dc.language.isoeng
dc.publisherSAGE PUBLICATIONS INC
dc.relation.ispartofCartilage
dc.rightsrestrictedAccess
dc.rights.holderCopyright SAGE PUBLICATIONS INC
dc.subjectosteochondral allograft transplant
dc.subjectknee fracture
dc.subjectfunctional outcomes
dc.subjectsurvivorship
dc.subject.otherautologous chondrocyte implantation
dc.subject.otherterm-follow-up
dc.subject.otherarticular-cartilage defects
dc.subject.othersurvivorship analysis
dc.subject.othermarrow stimulation
dc.subject.otherfemoral condyle
dc.subject.otherfailure
dc.subject.otherlesions
dc.subject.otheroutcomes
dc.subject.otherjoints
dc.subject.wosOrthopedics
dc.titleFresh Osteochondral Allograft Transplantation for Fractures of the Knee
dc.typearticle
dc.type.categoryoriginal article
dc.type.versionpublishedVersion
dspace.entity.typePublication
hcfmusp.affiliation.countryEstados Unidos
hcfmusp.affiliation.countryisous
hcfmusp.author.externalGRACITELLI, Guilherme C.:Univ Fed Sao Paulo, Dept Orthopaed Surg, Sao Paulo, Brazil
hcfmusp.author.externalMCCAULEY, Julie C.:Scripps Clin, Shiley Ctr Orthopaed Res & Educ, La Jolla, CA 92037 USA
hcfmusp.author.externalPULIDO, Pamela A.:Scripps Clin, Shiley Ctr Orthopaed Res & Educ, La Jolla, CA 92037 USA
hcfmusp.author.externalBUGBEE, William D.:Scripps Clin, Div Orthopaed Surg, 10666 North Torrey Pines Rd,MS 116, La Jolla, CA 92037 USA
hcfmusp.citation.scopus19
hcfmusp.contributor.author-fmusphcLUIS EDUARDO PASSARELLI TIRICO
hcfmusp.description.beginpage155
hcfmusp.description.endpage161
hcfmusp.description.issue2
hcfmusp.description.volume8
hcfmusp.origemWOS
hcfmusp.origem.pubmed28345414
hcfmusp.origem.scopus2-s2.0-85015750547
hcfmusp.origem.wosWOS:000397452100008
hcfmusp.publisher.cityTHOUSAND OAKS
hcfmusp.publisher.countryUSA
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