Renal function in children with congenital neurogenic bladder

Página do item simplificado
dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorOLANDOSKI, Karen Previdi
dc.contributor.authorKOCH, Vera
dc.contributor.authorTRIGO-ROCHA, Flavio Eduardo
dc.date.accessioned2017-11-27T16:39:43Z
dc.date.available2017-11-27T16:39:43Z
dc.date.issued2011
dc.description.abstractAIMS: Preservation of renal function in children with congenital neurogenic bladder is an important goal of treatment for the disease. This study analyzed the evolution of renal function in patients with congenital neurogenic bladder. METHODS: We reviewed the records of 58 pediatric patients with respect to the following attributes: gender, age, etiology of neurogenic bladder, reason for referral, medical/surgical management, episodes of treated urinary tract infections, urodynamics, DMSA scintigraphy, weight, height, blood pressure, glomerular filtration rate, microalbuminuria and metabolic acidosis. Statistical analysis was performed, adopting the 5% significance level. RESULTS: The mean age at presentation was 4.2 +/- 3.5 years. Myelomeningocele was the most frequent etiology (71.4%). Recurrent urinary tract infection was the reason for referral in 82.8% of the patients. Recurrent urinary tract infections were diagnosed in 84.5% of the patients initially; 83.7% of those patients experienced improvement during follow-up. The initial mean glomerular filtration rate was 146.7 +/- 70.1 mL/1.73 m(2)/min, and the final mean was 193.6 +/- 93.6 mL/1.73 m(2)/min, p = 0.0004. Microalbuminuria was diagnosed in 54.1% of the patients initially and in 69% in the final evaluation. Metabolic acidosis was present in 19% of the patients initially and in 32.8% in the final assessment. CONCLUSIONS: Patient referral to a pediatric nephrologist was late. A reduction in the number of urinary tract infections was observed with adequate treatment, but microalbuminuria and metabolic acidosis occurred frequently despite adequate management.
dc.description.indexMEDLINE
dc.identifier.citationCLINICS, v.66, n.2, p.189-195, 2011
dc.identifier.doi10.1590/S1807-59322011000200002
dc.identifier.issn1807-5932
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/23823
dc.language.isoeng
dc.publisherHOSPITAL CLINICAS, UNIV SAO PAULO
dc.relation.ispartofClinics
dc.rightsopenAccess
dc.rights.holderCopyright HOSPITAL CLINICAS, UNIV SAO PAULO
dc.subjectNeurogenic Bladder
dc.subjectMicroalbuminuria
dc.subjectAcidosis
dc.subjectChildren
dc.subjectRenal Function
dc.subject.otherglomerular-filtration-rate
dc.subject.otherneuropathic bladder
dc.subject.otherkidney-function
dc.subject.othermyelomeningocele
dc.subject.othergrowth
dc.subject.othermanagement
dc.subject.otherstature
dc.subject.othersize
dc.subject.wosMedicine, General & Internal
dc.titleRenal function in children with congenital neurogenic bladder
dc.typearticle
dc.type.categoryoriginal article
dc.type.versionpublishedVersion
dspace.entity.typePublication
hcfmusp.citation.scopus25
hcfmusp.contributor.author-fmusphcKAREN PREVIDI OLANDOSKI
hcfmusp.contributor.author-fmusphcVERA HERMINA KALIKA KOCH
hcfmusp.contributor.author-fmusphcFLAVIO EDUARDO TRIGO ROCHA
hcfmusp.description.beginpage189
hcfmusp.description.endpage195
hcfmusp.description.issue2
hcfmusp.description.volume66
hcfmusp.origemWOS
hcfmusp.origem.pubmed21484032
hcfmusp.origem.scopus2-s2.0-79955495229
hcfmusp.origem.wosWOS:000289365200002
hcfmusp.publisher.citySAO PAULO
hcfmusp.publisher.countryBRAZIL
hcfmusp.relation.referenceAmerican Diabetes Association Clinical Practice Recommendations, 2001, DIABETES CARE S1, V24, pS1
hcfmusp.relation.referenceSCHWARTZ GJ, 1987, PEDIATR CLIN N AM, V34, P571
hcfmusp.relation.referenceDik P, 2006, EUR UROL, V49, P908, DOI 10.1016/j.eururo.2005.12.056
hcfmusp.relation.referencede Jong PE, 2006, J AM SOC NEPHROL, V17, P2120, DOI 10.1681/ASN.2006010097
hcfmusp.relation.referenceWiggins RC, 2007, KIDNEY INT, V71, P1205, DOI 10.1038/sj.ki.5002222
hcfmusp.relation.referenceDIBLEY MJ, 1987, AM J CLIN NUTR, V46, P749
hcfmusp.relation.referenceBattle D. C., 1981, NEW ENGL J MED, V304, P373
hcfmusp.relation.referenceCASS AS, 1984, J UROLOGY, V132, P521
hcfmusp.relation.referenceCASS AS, 1984, J UROLOGY, V132, P526
hcfmusp.relation.referenceDel Gado R, 2003, J UROLOGY, V170, P1960, DOI 10.1097/01.ju.0000091874.91613.af
hcfmusp.relation.referenceGHONIEM GM, 1990, J UROLOGY, V144, P1440
hcfmusp.relation.referenceHAYESALL.MC, 1972, DEV MED CHILD NEUROL, V14, P59
hcfmusp.relation.referenceKari JA, 2006, PEDIATR NEPHROL, V21, P517, DOI 10.1007/s00467-006-0034-5
hcfmusp.relation.referenceMingin GC, 2002, PEDIATRICS, V110, P1193, DOI 10.1542/peds.110.6.1193
hcfmusp.relation.referenceRodriguez Soriano Juan, 2002, Journal of the American Society of Nephrology, V13, P2160, DOI 10.1097/01.ASN.0000023430.92674.E5
hcfmusp.relation.referenceROSENBLUM MF, 1983, DEV MED CHILD NEUROL, V25, P338
hcfmusp.relation.referenceStevens LA, 2006, NEW ENGL J MED, V354, P2473, DOI 10.1056/NEJMra054415
hcfmusp.relation.referenceSutherland RW, 1997, J UROLOGY, V158, P1265, DOI 10.1016/S0022-5347(01)64450-1
hcfmusp.relation.referenceUlsenheimer MMM, 2004, ARQ NEURO-PSIQUIAT, V62, P963, DOI 10.1590/S0004-282X2004000600006
hcfmusp.scopus.lastupdate2024-05-10
relation.isAuthorOfPublication9bcc1346-b1ad-4788-95c6-638baa73d7d9
relation.isAuthorOfPublication390d7207-aa42-48e6-ae76-b1d246aad21a
relation.isAuthorOfPublicationa7ab2647-01d7-46a6-bede-c3d7635bc6e3
relation.isAuthorOfPublication.latestForDiscovery9bcc1346-b1ad-4788-95c6-638baa73d7d9
Arquivos
Pacote Original
Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
art_OLANDOSKI_Renal_function_in_children_with_congenital_neurogenic_bladder_2011.PDF
Tamanho:
290.33 KB
Formato:
Adobe Portable Document Format
Descrição:
publishedVersion (English)
Baixar
Coleções
Artigos e Materiais de Revistas Científicas - HC/ICr
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - LIM/36