Classification of MRI under the Presence of Disease Heterogeneity using Multi-Task Learning: Application to Bipolar Disorder

dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorWANG, Xiangyang
dc.contributor.authorZHANG, Tianhao
dc.contributor.authorCHAIM, Tiffany M.
dc.contributor.authorZANETTI, Marcus V.
dc.contributor.authorDAVATZIKOS, Christos
dc.date.accessioned2016-03-24T15:02:28Z
dc.date.available2016-03-24T15:02:28Z
dc.date.issued2015
dc.description.abstractHeterogeneity in psychiatric and neurological disorders has undermined our ability to understand the pathophysiology underlying their clinical manifestations. In an effort to better distinguish clinical subtypes, many disorders, such as Bipolar Disorder, have been further sub-categorized into subgroups, albeit with criteria that are not very clear, reproducible and objective. Imaging, along with pattern analysis and classification methods, offers promise for developing objective and quantitative ways for disease subtype categorization. Herein, we develop such a method using learning multiple tasks, assuming that each task corresponds to a disease subtype but that subtypes share some common imaging characteristics, along with having distinct features. In particular, we extend the original SVM method by incorporating the sparsity and the group sparsity techniques to allow simultaneous joint learning for all diagnostic tasks. Experiments on Multi-Task Bipolar Disorder classification demonstrate the advantages of our proposed methods compared to other state-of-art pattern analysis approaches.
dc.description.conferencedateOCT 05-09, 2015
dc.description.conferencelocalMunich, GERMANY
dc.description.conferencename18th International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI)
dc.description.indexWoS
dc.description.sponsorshipNIA NIH HHS
dc.identifier.citationMEDICAL IMAGE COMPUTING AND COMPUTER-ASSISTED INTERVENTION - MICCAI 2015, PT I, v.9349, p.125-132, 2015
dc.identifier.doi10.1007/978-3-319-24553-9_16
dc.identifier.isbn978-3-319-24553-9; 978-3-319-24552-2
dc.identifier.issn0302-9743
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/13785
dc.language.isoeng
dc.publisherSPRINGER INT PUBLISHING AG
dc.relation.ispartofMedical Image Computing and Computer-Assisted Intervention - Miccai 2015, Pt I
dc.relation.ispartofseriesLecture Notes in Computer Science
dc.rightsrestrictedAccess
dc.rights.holderCopyright SPRINGER INT PUBLISHING AG
dc.subject.otherselection
dc.subject.otherregression
dc.subject.otherlasso
dc.subject.wosComputer Science, Artificial Intelligence
dc.subject.wosComputer Science, Interdisciplinary Applications
dc.subject.wosComputer Science, Theory & Methods
dc.subject.wosRadiology, Nuclear Medicine & Medical Imaging
dc.titleClassification of MRI under the Presence of Disease Heterogeneity using Multi-Task Learning: Application to Bipolar Disorder
dc.typeconferenceObject
dc.type.categoryproceedings paper
dc.type.versionpublishedVersion
dspace.entity.typePublication
hcfmusp.affiliation.countryEstados Unidos
hcfmusp.affiliation.countryChina
hcfmusp.affiliation.countryisocn
hcfmusp.affiliation.countryisous
hcfmusp.author.externalWANG, Xiangyang:Univ Penn, Ctr Biomed Image Comp & Analyt, Philadelphia, PA 19104 USA; Univ Penn, Dept Radiol, Philadelphia, PA 19104 USA; Shanghai Univ, Sch Commun & Informat Engn, Shanghai 200444, Peoples R China
hcfmusp.author.externalZHANG, Tianhao:Univ Penn, Ctr Biomed Image Comp & Analyt, Philadelphia, PA 19104 USA; Univ Penn, Dept Radiol, Philadelphia, PA 19104 USA
hcfmusp.author.externalDAVATZIKOS, Christos:Univ Penn, Ctr Biomed Image Comp & Analyt, Philadelphia, PA 19104 USA; Univ Penn, Dept Radiol, Philadelphia, PA 19104 USA
hcfmusp.contributor.author-fmusphcTIFFANY MOUKBEL CHAIM AVANCINI
hcfmusp.contributor.author-fmusphcMARCUS VINICIUS ZANETTI
hcfmusp.description.beginpage125
hcfmusp.description.endpage132
hcfmusp.description.volume9349
hcfmusp.origemWOS
hcfmusp.origem.wosWOS:000366205700016
hcfmusp.publisher.cityCHAM
hcfmusp.publisher.countrySWITZERLAND
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relation.isAuthorOfPublication.latestForDiscovery8895fec3-75e6-410b-a0b3-e2fe014ad865
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