Ventilation Distribution Studies Comparing Technegas and ""Gallgas"" Using (GaCl3)-Ga-68 as the Label

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Citações na Scopus
27
Tipo de produção
article
Data de publicação
2011
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
SOC NUCLEAR MEDICINE INC
Autores
VELIKYAN, Irina
LANGSTROM, Bengt
SORENSEN, Jens
ULIN, Johan
MARIPUU, Enn
SANDSTROM, Mattias
WIDSTROM, Charles
HEDENSTIERNA, Goran
Citação
JOURNAL OF NUCLEAR MEDICINE, v.52, n.2, p.206-209, 2011
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Ventilation distribution can be assessed by SPECT with Technegas. This study was undertaken in piglets with different degrees of ventilation inhomogeneity to compare PET using Ga-68-labeled pseudogas or ""Gallgas"" with Technegas. Methods: Twelve piglets were studied in 3 groups: control, lobar obstruction, and diffuse airway obstruction. Two more piglets were assessed for lung volume (functional residual capacity). Results: In controls, SPECT and PET images showed an even distribution of radioactivity. With lobar obstruction, the absence of ventilation of the obstructed lobe was visible with both techniques. In diffuse airway obstruction, SPECT images showed an even distribution of radioactivity, and PET images showed more varied radioactivity over the lung. Conclusion: PET provides detailed ventilation distribution images and a better appreciation of ventilation heterogeneity. Gallgas with PET is a promising new diagnostic tool for the assessment of ventilation distribution.
Palavras-chave
ventilation, Technegas, SPECT, Ga-68-pseudogas, PET
URI
https://observatorio.fm.usp.br/handle/OPI/24053
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Coleções
Artigos e Materiais de Revistas Científicas - LIM/09