Modifiable risk factors for glioblastoma: a systematic review and meta-analysis
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Tipo de produção
article
Data de publicação
2023
Título da Revista
ISSN da Revista
Título do Volume
Editora
SPRINGER
Citação
NEUROSURGICAL REVIEW, v.46, n.1, article ID 143, 11p, 2023
Resumo
Glioblastoma (GBM) is the most common and aggressive glioma histological subtype, associated with high disability and poor survival. The etiology of this condition is still mostly unknown, and evidence about risk factors is elusive. The aim of this study is to identify modifiable risk factors for GBM. Electronic search was performed by two reviewers independently using the keywords and MeSH terms 'glioblastoma' OR 'glioma' OR 'brain tumor' AND 'risk factor'. The inclusion criteria were (1) observational studies or experimental studies on humans, (2) studies assessing the association between glioblastoma and exposure to modifiable conditions, and (3) studies published in English or Portuguese. Studies on the pediatric population or about exposure to ionizing radiation were excluded. A total of 12 studies were included. Seven were case-control studies, and five were cohort studies. The risk factors assessed included body mass index, alcohol consumption, exposure to magnetic fields, diabetes mellitus type 2 (DM2), and use of non-steroidal anti-inflammatory drugs (NSAID). No significant link was found between GBM incidence and DM2 or magnetic field exposure. On the other hand, higher BMI, alcohol consumption, and NSAID use demonstrated a protective effect on GMB risk. However, given the limited number of studies, it is not possible to obtain a behavioral recommendation; instead, these findings are relevant to guide future basic scientific studies on GBM oncogenesis.
Palavras-chave
Glioblastoma, Brain tumor, Risk factor, Exposure
Referências
- Baglietto L, 2011, INT J CANCER, V128, P1929, DOI 10.1002/ijc.25770
- Banks WA, 2012, PHARMACOL THERAPEUT, V136, P82, DOI 10.1016/j.pharmthera.2012.07.006
- Barami K, 2017, WORLD NEUROSURG, V106, P300, DOI [10.1016/j.wneu.2017.06.164, 10.1016/J.WNEU.2017.06.164]
- BOEING H, 1993, INT J CANCER, V53, P561, DOI 10.1002/ijc.2910530406
- Bondy ML, 2008, CANCER-AM CANCER SOC, V113, P1953, DOI 10.1002/cncr.23741
- Braganza MZ, 2014, BRIT J CANCER, V110, P242, DOI 10.1038/bjc.2013.611
- Buccoliero AM, 2006, CLIN NEUROPATHOL, V25, P59
- Cardis E, 2010, INT J EPIDEMIOL, V39, P675, DOI 10.1093/ije/dyq079
- Cote DJ, 2021, EUR J EPIDEMIOL, V36, P965, DOI 10.1007/s10654-021-00800-1
- Daugherty SE, 2011, CANCER PREV RES, V4, P2027, DOI 10.1158/1940-6207.CAPR-11-0274
- de Wit MCY, 2004, NEUROLOGY, V63, P535, DOI 10.1212/01.WNL.0000133398.11870.9A
- Deininger MH, 1999, J NEUROIMMUNOL, V95, P202, DOI 10.1016/S0165-5728(98)00257-4
- Deitrich R, 2006, ALCOHOL RES HEALTH, V29, P266
- Disney-Hogg L, 2018, BRIT J CANCER, V118, P1020, DOI 10.1038/s41416-018-0009-x
- Dziurzynski K, 2012, NEURO-ONCOLOGY, V14, P246, DOI 10.1093/neuonc/nor227
- Edlinger M, 2012, J HYPERTENS, V30, P290, DOI 10.1097/HJH.0b013e32834e9176
- Fanelli GN, 2021, GENES-BASEL, V12, DOI 10.3390/genes12030445
- Font-Burgada J, 2016, CELL METAB, V23, P48, DOI 10.1016/j.cmet.2015.12.015
- GILES GG, 1994, INT J CANCER, V59, P357, DOI 10.1002/ijc.2910590311
- HOCHBERG F, 1990, J NEURO-ONCOL, V8, P55
- Hu JF, 1999, INT J CANCER, V81, P20, DOI 10.1002/(SICI)1097-0215(19990331)81:1<20::AID-IJC4>3.0.CO;2-2
- Inskip PD, 1995, EPIDEMIOL REV, V17, P382
- Joki T, 2000, CANCER RES, V60, P4926
- Kabat GC, 2018, CANCER EPIDEMIOL, V54, P71, DOI 10.1016/j.canep.2018.03.008
- Kuan AS, 2019, NEURO-ONCOLOGY, V21, P944, DOI 10.1093/neuonc/noz013
- Kyrgiou M, 2017, BMJ-BRIT MED J, V356, DOI 10.1136/bmj.j477
- Lee M, 1997, CANCER CAUSE CONTROL, V8, P13, DOI 10.1023/A:1018470802969
- LOSCHER W, 1994, LIFE SCI, V54, P1531, DOI 10.1016/0024-3205(94)90024-8
- Montemurro N, 2023, NEUROL INT, V15, P595, DOI 10.3390/neurolint15020037
- Montemurro N, 2020, INT J ENV RES PUB HE, V17, DOI 10.3390/ijerph17228501
- Neglia JP, 2006, J NATL CANCER I, V98, P1528, DOI 10.1093/jnci/djj411
- Niedermaier T, 2015, NEUROLOGY, V85, P1342, DOI 10.1212/WNL.0000000000002020
- Ohgaki H, 2010, CURR OPIN NEUROL, V23, P583, DOI 10.1097/WCO.0b013e3283405b5f
- Omuro A, 2013, JAMA-J AM MED ASSOC, V310, P1842, DOI 10.1001/jama.2013.280319
- Ostrom QT, 2015, NEURO-ONCOLOGY, V16, P1, DOI [10.1093/neuonc/nov189, 10.1093/neuonc/nou327, 10.1093/neuonc/nou223]
- Ostrom QT, 2014, NEURO-ONCOLOGY, V16, P896, DOI 10.1093/neuonc/nou087
- Ostrom QT, 2011, CURR NEUROL NEUROSCI, V11, P329, DOI 10.1007/s11910-011-0189-8
- Perdiki M, 2007, MOL CELL BIOCHEM, V295, P75, DOI 10.1007/s11010-006-9275-7
- Pignataro L, 2007, J NEUROSCI, V27, P12957, DOI 10.1523/JNEUROSCI.4142-07.2007
- RYAN P, 1992, INT J CANCER, V51, P20, DOI 10.1002/ijc.2910510105
- Scheurer ME, 2011, INT J CANCER, V129, P2290, DOI 10.1002/ijc.25883
- Seitz HK, 2007, NAT REV CANCER, V7, P599, DOI 10.1038/nrc2191
- Sergentanis TN, 2015, PLOS ONE, V10, DOI 10.1371/journal.pone.0136974
- Shono T, 2001, CANCER RES, V61, P4375
- Sivak-Sears NR, 2004, AM J EPIDEMIOL, V159, P1131, DOI 10.1093/aje/kwh153
- THERIAULT G, 1994, AM J EPIDEMIOL, V139, P550, DOI 10.1093/oxfordjournals.aje.a117046
- Villeneuve PJ, 2002, INT J EPIDEMIOL, V31, P210, DOI 10.1093/ije/31.1.210
- Wells G., NEWCASTLE OTTAWA SCA
- Wiedmann M, 2013, BRIT J CANCER, V109, P289, DOI 10.1038/bjc.2013.304
- Wiedmann MKH, 2017, NEURO-ONCOLOGY, V19, P976, DOI 10.1093/neuonc/now272
- Wirsching Hans-Georg, 2016, Handb Clin Neurol, V134, P381, DOI 10.1016/B978-0-12-802997-8.00023-2