Can we predict who will benefit from the deep inspiration breath hold (DIBH) technique for breast cancer irradiation?

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Citações na Scopus
0
Tipo de produção
article
Data de publicação
2023
DOI
Scopus
Web of Science
PubMed
Dimensions
Título da Revista
ISSN da Revista
Título do Volume
Editora
VIA MEDICA
Autores
ABE, Ricardo Y.
Citação
REPORTS OF PRACTICAL ONCOLOGY AND RADIOTHERAPY, v.28, n.5, p.582-591, 2023
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Background: The objective was to explore the clinical use of an ""in-house"" prototype developed to monitor respiratory motion to implement the deep inspiration breath hold technique (DIBH), compare dosimetric differences, and assess whether simple anatomic metrics measured on free breathing (FB) computed tomography scan (CT) can help in selecting patients that would benefit the most from the technique. Materials and methods: A prospective study was conducted on patients with left breast cancer with an indication of adjuvant radiotherapy for breast only. Treatment simulation consisted of four series of CTs: the first during FB and three in DIBH to assess the reproducibility and stability of apnea. Contouring was based on the RTOG atlas, and planning was done in both FB and DIBH. Dosimetric and geometric parameters were assessed and compared between FB and DIBH. Results: From June 2020 to December 2021, 30 patients with left breast cancer were recruited. Overall, the DIBH technique presented a mean dose reduction of 24% in the heart and 30% in the left anterior descendent coronary artery (LAD) (p < 0.05). The only geometric parameter correlated to a 30% dose reduction in the mean heart dose and LAD doses was the anterolateral distance from the heart to the chest wall of at least 1.5 cm measured on FB (p < 0.0001). Conclusion: The prototype enabled the use of the DIBH technique with dose reductions in the heart and LAD. The benefit of the DIBH technique can be predicted on FB CT by measuring the distance between the heart and chest wall at the treatment isocenter.
Palavras-chave
breast cancer, radiotherapy, deep inspiration breath-hold (DIBH), free breathing (FB)
URI
https://observatorio.fm.usp.br/handle/OPI/59220
Referências
  1. Abe O, 2005, LANCET, V366, P2087, DOI 10.1016/s0140-6736(05)66544-0
  2. Appelt AL, 2013, CLIN ONCOL-UK, V25, P147, DOI 10.1016/j.clon.2012.07.012
  3. Comsa D, 2014, PRACT RADIAT ONCOL, V4, P298, DOI 10.1016/j.prro.2013.10.006
  4. Darby SC, 2013, NEW ENGL J MED, V368, P987, DOI 10.1056/NEJMoa1209825
  5. Early Breast Canc Trialists Collab, 2011, LANCET, V378, P1707, DOI 10.1016/S0140-6736(11)61629-2
  6. Eldredge-Hindy H, 2015, PRACT RADIAT ONCOL, V5, P4, DOI 10.1016/j.prro.2014.06.004
  7. Hayden AJ, 2012, J MED IMAG RADIAT ON, V56, P464, DOI 10.1111/j.1754-9485.2012.02405.x
  8. Herrmann J, 2020, NAT REV CARDIOL, V17, P474, DOI 10.1038/s41569-020-0348-1
  9. Jensen CA, 2017, J APPL CLIN MED PHYS, V18, P117, DOI 10.1002/acm2.12137
  10. Joo JH, 2015, RADIAT ONCOL, V10, DOI 10.1186/s13014-015-0573-7
  11. Korreman SS, 2006, RADIOTHER ONCOL, V80, P257, DOI 10.1016/j.radonc.2006.07.020
  12. Lee HY, 2013, RADIAT ONCOL J, V31, P239, DOI 10.3857/roj.2013.31.4.239
  13. Mendez LC, 2018, CLIN ONCOL-UK, V30, pE29, DOI 10.1016/j.clon.2017.09.003
  14. Nicolazzi MA, 2018, EUR REV MED PHARMACO, V22, P2175, DOI 10.26355/eurrev_201804_14752
  15. Nissen HD, 2013, RADIOTHER ONCOL, V106, P28, DOI 10.1016/j.radonc.2012.10.016
  16. Osman SOS, 2014, RADIOTHER ONCOL, V112, P17, DOI 10.1016/j.radonc.2014.04.004
  17. Piroth MD, 2019, STRAHLENTHER ONKOL, V195, P1, DOI 10.1007/s00066-018-1378-z
  18. Remouchamps VM, 2003, INT J RADIAT ONCOL, V55, P392, DOI 10.1016/S0360-3016(02)04143-3
  19. Rochet N, 2015, PRACT RADIAT ONCOL, V5, pE127, DOI 10.1016/j.prro.2014.08.003
  20. Sardaro A, 2012, RADIOTHER ONCOL, V103, P133, DOI 10.1016/j.radonc.2012.02.008
  21. Sixel KE, 2001, INT J RADIAT ONCOL, V49, P199, DOI 10.1016/S0360-3016(00)01455-3
  22. Sung H, 2021, CA-CANCER J CLIN, V71, P209, DOI 10.3322/caac.21660
  23. Swanson T, 2013, AM J CLIN ONCOL-CANC, V36, P24, DOI 10.1097/COC.0b013e31823fe481
  24. Tanguturi SK, 2015, PRACT RADIAT ONCOL, V5, P358, DOI 10.1016/j.prro.2015.06.002
  25. Taylor CW, 2015, CLIN ONCOL-UK, V27, P621, DOI 10.1016/j.clon.2015.06.007
  26. van den Bogaard VAB, 2017, J CLIN ONCOL, V35, P1171, DOI 10.1200/JCO.2016.69.8480
  27. Vennarini S, 2013, BRIT J RADIOL, V86, DOI 10.1259/bjr.20120643
  28. Wang W, 2012, INT J RADIAT ONCOL, V82, P386, DOI 10.1016/j.ijrobp.2010.09.026

Coleções
Artigos e Materiais de Revistas Científicas - HC/InRad