ZILDA NAJJAR PRADO DE OLIVEIRA
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/53 - Laboratório de Micologia, Hospital das Clínicas, Faculdade de Medicina
LIM/53 - Laboratório de Micologia, Hospital das Clínicas, Faculdade de Medicina
40 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 40
bookPart Fotoproteção(2022) MIOTTO, Isadora Zago; SAMORANO, Luciana de Paula; OLIVEIRA, Zilda Najjar Prado debookPart Dermatozoonoses(2016) OLIVEIRA, Zilda Najjar Prado de; LOBO, Alice Zoghbi Coelho- Tuberous sclerosis complex: review based on new diagnostic criteria(2018) PORTOCARRERO, Larissa Karine Leite; QUENTAL, Klicia Novais; SAMORANO, Luciana Paula; OLIVEIRA, Zilda Najjar Prado de; RIVITTI-MACHADO, Maria Cecilia da MattaTuberous sclerosis complex is a multisystemic, autosomal dominant genetic disorder with complete penetrance, that can evolve with hamartomas in multiple organs, such as skin, central nervous system, kidney and lung. Due to the wide phenotypic variability, the disease is often not recognized. Tuberous sclerosis complex affects one in 10,000 newborns and most patients are diagnosed during the first 15 months of life. The diagnostic criteria for tuberous sclerosis were reviewed in 2012, at the second International Tuberous Sclerosis Complex Consensus Conference. The diagnosis is based on genetic criteria, by the identification of inactivating pathogenic mutation of tumor suppressor genes TSC1 and TSC2, and clinical criteria, including cutaneous, renal, pulmonary, cardiac and neurological manifestations. The treatment of tuberous sclerosis complex consists, mainly, in management of the symptoms caused by hamartomas and in prevention of organ failure. Multidisciplinary approach is recommended, in order to obtain better clinical outcomes.
conferenceObject Darier disease: Long-term treatment with systemic retinoids at a tertiary hospital(2020) VIEIRA, Marina Lino; OLIVEIRA, Zilda Najjar Prado de; SAMORANO, Luciana Paula; PESS, Daiana; RIVITTI-MACHADO, Maria CeciliaconferenceObject Translation and validation into Brazilian Portuguese of a quality of life instrument for epidermolysis bullosa patients (QOLEB)(2014) CESTARI, Tania; PRATI, Clarissa; MURRELL, Dedee; MENEGON, Doris; MACHADO, Maria Cecilia; OLIVEIRA, Zilda Prado de- Underrecognition of epidermolysis bullosa pruriginosa(2015) CHA, Caroline Coronado; SAMORANO, Luciana Paula; DACACHE, Fernanda Motta; RIVITTI-MACHADO, Maria Cecilia da Matta; OLIVEIRA, Zilda Najjar Prado de
bookPart Dermatite da área das fraldas(2022) FERNANDES, Juliana Dumêt; OLIVEIRA, Zilda Najjar Prado de- Corticosteroid use in urticaria multiforme cases Response(2017) SAMORANO, Luciana P.; FERNANDEZ, Vanessa V.; VALENTE, Neusa Y. S.; ARNONE, Marcelo; NICO, Marcello M. S.; RIVITTI-MACHADO, Maria C. M.; OLIVEIRA, Zilda N. P.; CRIADO, Paulo R.
article 36 Citação(ões) na Scopus Prevenção e cuidados com a pele da criança e do recém-nascido(2011) FERNANDES, Juliana Dumet; MACHADO, Maria Cecilia Rivitti; OLIVEIRA, Zilda Najjar Prado deNeonatal skin suffers a progressive adaptation to the extrauterine environment and special care is needed during this period. This skin is very sensitive, thin and fragile. Immaturity of the epidermal barrier reduces the defense against the excessive proliferation of microbes and makes the skin more vulnerable to trauma and percutaneous drug toxicity. Because of the peculiar characteristics of newborn, infant and children's skin, the use of cosmetic products designed for hygiene and protection requires caution. In order to preserve the integrity of neonatal and child's skin, this article reviewed basic preventive care practices in relation to hygiene, bathing, cleansing agents, topical products and their percutaneous toxicity.- Translation, cross-cultural adaptation and validation of the Quality of Life Evaluation in Epidermolysis Bullosa instrument in Brazilian Portuguese(2016) CESTARI, Tania; PRATI, Clarissa; MENEGON, Doris B.; OLIVEIRA, Zilda N. Prado; MACHADO, Maria Cecilia R.; DUMET, Juliana; NAKANO, Juliana; MURRELL, Dedee F.BackgroundThe Quality of Life Evaluation in Epidermolysis Bullosa (QoLEB) questionnaire was developed for use in English-speaking individuals. ObjectivesThe aims of this study were to translate the QoLEB into Brazilian Portuguese, to culturally adapt it, and to verify its reliability and validity. MethodsThe study followed the steps proposed by the World Health Organization, which include: translation; evaluation by a panel of experts and patients; back translation; and linguistic and cultural adaptation. All subjects were examined and assessed using the QoLEB and the Dermatology Life Quality Index (DLQI) or the Children's Dermatology Life Quality Index (CDLQI). Translation and cultural and linguistic adaptation were conducted by 10 patients, three translators, and the bilingual authors. ResultsThe population was composed of 40 children (mean age: 8,15 years) and 17 adults (mean age: 33 years). Among the children, eight had epidermolysis bullosa (EB) simplex (EBS), one had junctional EB (JEB), and 31 had dystrophic EB (DEB). In the adult group, four of the subjects had EBS, one had JEB, and 12 had DEB. Mean standard deviation (SD) scores on the QoLEB in children were 10.60 +/- 7.13 in EBS subjects, 9.71 +/- 7.87 in children with dominant DEB (DDEB), and 14.25 +/- 9.67 in children with recessive DEB (RDEB). Mean +/- SD scores in adults were 12.50 +/- 9.95 in EBS subjects, 12.00 +/- 5.83 in DDEB subjects, and 20.20 +/- 9.21 in RDEB subjects. The QoLEB-BP (Brazilian Portuguese) showed high internal consistency (Cronbach's = 0.88) and high test-retest reliability (intraclass correlation coefficient: 0.70), confirming the internal consistency and reproducibility of this Portuguese version. There were significant correlations between QoLEB scores and both CDLQI (Pearson's r = 0.688, P < 0.002) and DLQI (Pearson's r = 0.807, P < 0.001) scores. ConclusionsEpidermolysis bullosa has marked impacts on the lives of EB patients and their families, which are strongly correlated with disease severity. The Brazilian Portuguese version of the QoLEB is validated and can be recommended for use in subsequent studies.