Consensus of the Brazilian Society of Infectious Diseases and Brazilian Society of Clinical Oncology on the management and treatment of Kaposi's sarcoma
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Citações na Scopus
15
Tipo de produção
article
Data de publicação
2014
Título da Revista
ISSN da Revista
Título do Volume
Editora
CONTEXTO
Autores
ARRUDA, Erico
JACOME, Alexandre Andrade dos Anjos
TOSCANO, Ana Luiza de Castro Conde
SILVESTRINI, Anderson Arantes
REGO, Andre Santa Barbara
WIERMANN, Evanius Garcia
CUNHA JR., Geraldo Felicio da
MELO, Heloisa Ramos Lacerda de
MOREJON, Karen Mirna Loro
GOLDANI, Luciano Zubaran
Citação
BRAZILIAN JOURNAL OF INFECTIOUS DISEASES, v.18, n.3, p.315-326, 2014
Resumo
Kaposi's sarcoma is a multifocal vascular lesion of low-grade potential that is most often present in mucocutaneous sites and usually also affects lymph nodes and visceral organs. The condition may manifest through purplish lesions, flat or raised with an irregular shape, gastrointestinal bleeding due to lesions located in the digestive system, and dyspnea and hemoptysis associated with pulmonary lesions. In the early 1980s, the appearance of several cases of Kaposi's sarcoma in homosexual men was the first alarm about a newly identified epidemic, acquired immunodeficiency syndrome. In 1994, it was finally demonstrated that the presence of a herpes virus associated with Kaposi's sarcoma called HHV-8 or Kaposi's sarcoma herpes virus and its genetic sequence was rapidly deciphered. The prevalence of this virus is very high (about 50%) in some African populations, but stands between 2% and 8% for the entire world population. Kaposi's sarcoma only develops when the immune system is depressed, as in acquired immunodeficiency syndrome, which appears to be associated with a specific variant of the Kaposi's sarcoma herpes virus. There are no treatment guidelines for Kaposi's sarcoma established in Brazil, and thus the Brazilian Society of Clinical Oncology and the Brazilian Society of Infectious Diseases developed the treatment consensus presented here.
Palavras-chave
Kaposi's sarcoma, AIDS, Consensus, Cutaneous
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