Comunicações em Eventos - LIM/46
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A coleção de Comunicações em Eventos compreende trabalhos completos ou resumos de conferências, comunicações orais ou posteres, apresentados em congressos, seminários, jornadas, simpósios ou outros tipos de eventos de caráter técnico-científico ou artístico-cultural, publicados em anais impressos ou em meios eletrônicos.
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conferenceObject Genetic variation in HLA genes: impact on transplant compatibility in a Brazilian admixed population(2023) ANDRADE, Heloisa S.; SILVA, Marcio; NUNES, Kelly; PASSOS, Carlos Henrique; SENA, Alexandre C.; CASTELLI, Erick C.; DINARDO, Carla; SABINO, Ester C.; TEIXEIRA, Carolina M.; TELES, Dahra; AMORIM, Luiz; CUSTER, Brian; KELLY, Shannon; PORTO, Luis Cristovao; MEYER, DiogoconferenceObject Value of left ventricular longitudinal strain in predicting overt heart failure in patients with Chagas disease and preserved left ventricular ejection fraction(2023) NUNES, M. C. P. N.; FERREIRA, A. M. F.; SILVA, J. L. P. S.; CARVALHO, V. T. C.; SANTOS-JUNIOR, O. R. S. J.; CARDOSO, C. S. C.; OLIVEIRA, L. C. O.; SANTOS, A. C. J. S.; CRUZ, D. S. C.; LEITE, S. F. L.; JESUS, A. P. J.; HAIKAL, D. S. A. H.; SABINO, E. C. S.; RIBEIRO, A. L. P. R.- Exploring the prognostic significance and important phenotypic and genotypic associations of neural network-derived electrocardiographic features(2023) SAU, Arunashis; GIATTI, Luana; NG, Fu Siong; PETERS, Nicholas; SHIPLEY, Martin; BARRETO, Sandhi; PASTIKA, Libor; RIBEIRO, Antonio; SABINO, Ester; WARE, James; MCGURK, Kathryn; ANDRSOVA, Irena; WU, Huiyi; MALIK, Marek; RIBEIRO, Antonio; ZHENG, Sean; O'REGAN, Declan; WAKS, Jonathan; ARDISSINO, Maddalena; BAJAJ, Nikesh; HNATKOVA, Katerina; SHI, Xili; MANDIC, Danilo; KRAMER, Daniel; BRITTON, Annie; CHEN, Jun Yu; NOVOTNY, Tomas
conferenceObject Recognition of Trypanosoma cruzi epitopes by IgG of benznidazole treated Chagas disease patients(2021) CARNERO, Luis Antonio Rodriguez; MONTEIRO, Jhonatas Sirino; SETUBAL, Joao Carlos; SABINO, Ester Cerdeira; NETO, Edecio Cunha; GIORDANO, Ricardo Jose- Exploring the prognostic significance and important phenotypic and genotypic associations of neural network-derived electrocardiographic features(2023) SAU, Arunashis; RIBEIRO, Antonio H.; MCGURK, Kathryn A.; PASTIKA, Libor; BAJAJ, Nikesh; ARDISSINO, Maddalena; CHEN, Jun Yu; WU, Huiyi; SHI, Xili; HNATKOVA, Katerina; ZHENG, Sean; BRITTON, Annie; SHIPLEY, Martin; ANDRSOVA, Irena; NOVOTNY, Tomas; SABINO, Ester; GIATTI, Luana; BARRETO, Sandhi M.; WAKS, Jonathan W.; KRAMER, Daniel B.; MANDIC, Danilo; PETERS, Nicholas S.; O'REGAN, Declan P.; MALIK, Marek; WARE, James S.; RIBEIRO, Antonio Luiz P; NG, Fu Siong
- Genetic determinants of telomere length from 109,122 ancestrally diverse whole-genome sequences in TOPMed(2022) TAUB, M. A.; CONOMOS, M. P.; KEENER, R.; IYER, K. R.; WEINSTOCK, J. S.; YANEK, L. R.; LANE, J.; MILLER-FLEMING, T. W.; BRODY, J. A.; RAFFIELD, L. M.; MCHUGH, C. P.; TELEN, M. J.; PALMER, N. D.; SHOEMAKER, M. B.; TIWARI, H. K.; TRACY, R. P.; WHITE, M. J.; ZHANG, Y.; WIGGINS, K. L.; WEISS, S. T.; VASAN, R. S.; ALBERT, C.; TAYLOR, K. D.; SHEU, W. H.-H.; SCIURBA, F.; SCHWARTZ, D. A.; ROTTER, J. I.; RODEN, D.; REDLINE, S.; BLACKWELL, T. W.; RABY, B. A.; MONTGOMERY, C. G.; LAURIE, C. A.; MITCHELL, B. D.; MEYERS, D. A.; MCGARVEY, S. T.; MAK, A. C. Y.; LOOS, R. J. F.; JAIN, D.; KUMAR, R.; KOOPERBERG, C.; THORNTON, T.; KONKLE, B. A.; O'CONNELL, J.; KELLY, S.; KARDIA, S. L. R.; KAPLAN, R.; HE, J.; GUI, H.; GILLILAND, F. D.; GELB, B. D.; GOGARTEN, S. M.; FORNAGE, M.; KERAMATI, A.; LAURIE, C. C.; ELLINOR, P. T.; ANDRADE, M. de; CORREA, A.; CHEN, Y.-D. I.; BOERWINKLE, E.; BARNES, K. C.; ASHLEY-KOCH, A. E.; ARNETT, D. K.; ABECASIS, G.; NICKERSON, D. A.; WILSON, J. G.; RICH, S. S.; LEVY, D.; RUCZINSKI, I.; MOSCATI, A.; AVIV, A.; COX, N. J.; PERRY, J. A.; ARMANIOS, M.; BATTLE, A.; PANKRATZ, N.; REINER, A. P.; ZHAO, W.; MATHIAS, R. A.; ARVANITIS, M.; NORTH, K. E.; SMITH, A. V.; HEAVNER, B.; BARWICK, L.; BECKER, L. C.; BIS, J. C.; BLANGERO, J.; BLEECKER, E. R.; BURCHARD, E. G.; ASLIBEKYAN, S.; CELEDóN, J. C.; BOWDEN, D. W.; CHANG, Y. P. C.; CUSTER, B.; DARBAR, D.; FUENTES, L. de las; DEMEO, D. L.; FREEDMAN, B. I.; GARRETT, M. E.; GLADWIN, M. T.; HECKBERT, S. R.; AUER, P. L.; PEYSER, P. A.; HIDALGO, B. A.; IRVIN, M. R.; ISLAM, T.; JOHNSON, W. C.; KAAB, S.; LAUNER, L.; LEE, J.; LIU, S.; RAFAELS, N.; SEIDMAN, C.; WEEKS, D. E.; WEN, F.; WHEELER, M. M.; WILLIAMS, L. K.; SINNER, M. F.; YANG, I. V.; CADE, B. E.; CHEN, Z.; CHO, M. H.; CUPPLES, L. A.; CURRAN, J. E.; DAYA, M.; PSATY, B. M.; DEKA, R.; ENG, C.; SILVERMAN, E. K.; FINGERLIN, T. E.; GUO, X.; HOU, L.; HWANG, S.-J.; JOHNSEN, J. M.; KENNY, E. E.; LEVIN, A. M.; LIU, C.; PERALTA, J. M.; MINSTER, R. L.; NEKHAI, S.; NASERI, T.; NOURAIE, M.; REUPENA, M. S.; SABINO, E. C.; SMITH, J. A.; SMITH, N. L.; LASKY-SU, J.; TAYLOR, J. G.Genetic studies on telomere length are important for understanding age-related diseases. Prior GWASs for leukocyte TL have been limited to European and Asian populations. Here, we report the first sequencing-based association study for TL across ancestrally diverse individuals (European, African, Asian, and Hispanic/Latino) from the NHLBI Trans-Omics for Precision Medicine (TOPMed) program. We used whole-genome sequencing (WGS) of whole blood for variant genotype calling and the bioinformatic estimation of telomere length in n = 109,122 individuals. We identified 59 sentinel variants (p < 5 × 10−9) in 36 loci associated with telomere length, including 20 newly associated loci (13 were replicated in external datasets). There was little evidence of effect size heterogeneity across populations. Fine-mapping at OBFC1 indicated that the independent signals colocalized with cell-type-specific eQTLs for OBFC1 (STN1). Using a multi-variant gene-based approach, we identified two genes newly implicated in telomere length, DCLRE1B (SNM1B) and PARN. In PheWAS, we demonstrated that our TL polygenic trait scores (PTSs) were associated with an increased risk of cancer-related phenotypes. © 2021
conferenceObject Differential IgG Repertoire in Individuals With Chagas Cardiomyopathy(2022) VENTURINI, Gabriela; BES, Taniela; KULA, Tomasz; LI, Mamie; SHROCK, Ellen; ELLEDGE, Stephen; SABINO, Ester Cerdeira; KRIEGER, Jose; PEREIRA, Alexandre; SEIDMAN, Jonathan G.; SEIDMAN, Christine E.conferenceObject Speckle-Tracking Echocardiography Improves Risk Stratification in Patients With Chagas Cardiomyopathy(2022) MAIA, Marcelo A.; SABINO, Ester Cerdeira; SILVA, Jose Luiz Padilha da; SILVA, Lea Oliveira-da; SANTOS-JUNIOR, Omar R.; MAIA, Ana Isabel Nobre; VERSIANI, Fellipe; FERREIRA, Ariela; RIBEIRO, Antonio Luiz; NUNES, Maria C.conferenceObject RELATIONSHIP OF GALECTIN-3 BIOMARKER FOR CLINICAL OUTCOMES IN A CHAGAS DISEASE COHORT FROM A BRAZILIAN ENDEMIC REGION(2021) MOREIRA, Carlos H.; FERNANDES, Fabio F.; OLIVEIRA, Lea C. De; BIERRENBACH, Ana L.; CARDOSO, Clareci; LORENZO, Claudia Di; FERREIRA, Ariela M.; VIEIRA, Thallyta M.; DAMASCENO, Renata F.; HAIKAL, Desiree S.; QUINTINO, Nayara D.; NUNES, Maria do Carmo; RIBERIO, Antonio Luiz; SABINO, Ester C.conferenceObject EVALUATING VIRAL GENOMICS AND DISEASE SEVERITY USING NANOPORE SEQUENCING: A PROOF-OF-CONCEPT ANALYSIS(2021) MARQUES, Beatriz Carvalho; CANDIDO, Darlan Silva; ESTOFOLETE, Cassia Fernanda; SACCHETTO, Livia; DUTRA, Karina Rocha; SALLES, Flavia; DOURADO, Fernanda Simoes; SABINO, Ester Cerdeira; FARIA, Nuno; NOGUEIRA, Mauricio LacerdaconferenceObject Risk of liver and non-liver-related mortality among hepatitis C virus and human immunodeficiency virus co-infected persons in a cohort of Brazilian blood donors: a twenty-year study(2020) RANES FILHO, Helio; CAPUANI, Ligia; BIERRENBACH, Ana Luiza; MEDRONI JUNIOR, Alfredo; BENZAKEN, Adele; MACHADO, Soraia; SABINO, Ester Cerdeira; WITKIN, Steven; MENDES-CORREA, Maria CassiaconferenceObject The symbiotic supplementation modulate gut microbiota, regulation beta-catenin expression and prevents weight gain in ob/ob mice with non-alcoholic fatty liver disease (NAFLD)(2020) DUARTE, Sebastiao Mauro Bezerra; STEFANO, Jose Tadeu; FRANCO, Lucas A. M.; MARTINS, Roberta Cristina Ruedas; BARBEIRO, Denise Frediani; NERI, Junia Marielle Teixeira Rodrigues; COGLIATI, Bruno; SABINO, Ester Cerdeira; CARRILHO, Flair Jose; OLIVEIRA, ClaudiaconferenceObject Immunogenicity and Safety of an Inactivated Virus Vaccine Against SARS-CoV-2 in Patients with Autoimmune Rheumatic Diseases(2021) MEDEIROS-RIBEIRO, Ana; AIKAWA, Nadia; SAAD, Carla Goncalves Schahin; YUKI, Emily Figueiredo Vieira Neves; PEDROSA, Tatiana do Nascimento; FUSCO, Solange; ROJO, Priscila; PEREIRA, Rosa; SHINJO, Samuel; ANDRADE, Danieli; SAMPAIO-BARROS, Percival; RIBEIRO, Carolina; DEVEZA, Giordano; MARTINS, Victor Adriano de Oliveira; SILVA, Clovis Artur; LOPES, Marta; DUARTE, Alberto; ANTONANGELO, Leila; SABINO, Ester; KALLAS, Esper; PASOTO, Sandra Gofinet; BONFA, Eloisa- Determinants of pregnancy outcome in pregnant women with a short cervix(2020) MORON, Antonio F.; WITKIN, Steven S.; HATANAKA, Alan R.; SARMENTO, Stephanno G.; CARVALHO, Francisco H.; FRANCA, Marcelo S.; HAMAMOTO, Tatiana K.; MATTAR, Rosiane; LINHARES, Iara M.; MINIS, Evelyn; SANUDO, Adriana; SABINO, Ester C.; RUDGE, Marilza V.; FORNEY, Larry
- Biomarkers in vaginal secretions predict short cervix and dominant bacterium in women at first conception(2020) SARMENTO, Stephanno G.; MORON, Antonio F.; FORNEY, Larry; HATANAKA, Alan R.; CARVALHO, Francisco H.; FRANCA, Marcelo S.; HAMAMOTO, Tatiana K.; MATTAR, Rosiane; LINHARES, Iara M.; MINIS, Evelyn; SANUDO, Adriana; SABINO, Ester C.; RUDGE, Marilza V.; WITKIN, Steven S.
conferenceObject VALIDATION OF AN ARTIFICIAL INTELLIGENCE ELECTROCARDIOGRAM BASED ALGORITHM FOR THE DETECTION OF LEFT VENTRICULAR SYSTOLIC DYSFUNCTION IN SUBJECTS WITH CHAGAS DISEASE(2021) ATTIA, Zachi Itzhak; RIBEIRO, Antonio; FRIEDMAN, Paul; NUNES, Maria Carmo; GOMES, Paulo; FERREIRA, Ariela; FIGUEIREDO, Bruno; SABINO, Ester; NOSEWORTHY, Peter; KAPA, Suraj; PEREL, Pablo; LOPEZ-JIMENEZ, FranciscoconferenceObject Level of literacy and clinical outcomes in patients with Chagas disease: SaMi-Trop project(2020) QUINTINO, N.; DAVID, G.; SABINO, E.; SILVA, J. L.; RIBEIRO, A. L.; FERREIRA, A.; OLIVEIRA, L.; OLIVEIRA, C.; CARDOSO, C.- Detection of human norovirus using next generation sequencing: Strain diversity and expanding whole-genome sequences availability from Brazil(2020) TINKER, R.; COSTA, A. C. Da; LEAL, E.; TAHMASEBI, R.; MILAGRES, F.; BRUSTULIN, R.; TELES, M. D. A. R.; LOBATO, M. C. A. B. S.; CHAGAS, R. T. Das; ABRAO, M. D. F. N. D. S.; SOARES, C. V. D. D. A.; DENG, X.; DELWART, E.; SABINO, E. C.; LUCHS, A.
- Genome Wide Association Analysis of Iron Overload in the Trans-Omics for Precision Medicine (TOPMed) Sickle Cell Disease Cohorts(2020) WEN, Fayuan; ROCK, Angela; SALOMON-ANDONIE, Juan; KURBAN, Gulriz; NIU, Xiaomei; WANG, Songping; ZHANG, Xu; GORDEUK, Victor R.; ZHANG, Yingze; NOURAIE, Seyed Mehdi; GLADWIN, Mark T.; ASHLEY-KOCH, Allison; TELEN, Marilyn J.; CUSTER, Brian; KELLY, Shannon; DINARDO, Carla Luana; SABINO, Ester; WONG, Quenna; TAYLOR, James G.; NEKHAI, Sergei
conferenceObject Validation of a Deep Neural Network Electrocardiographic-Age as a Mortality Predictor: The CODE Study(2020) PAIXAO, Gabriela; LIMA, Emilly M.; RIBEIRO, Antonio H.; GOMES, Paulo R.; OLIVEIRA, Derick; PINTO JR., Marcelo M.; SABINO, Ester; BARRETO, Sandhi; GIATTI, Luana; LOTUFO, Paulo A. Andrade; DUNCAN, Bruce; MEIRA JR., Wagner; SCHON, Thomas; RIBEIRO, Antonio L.