Livros e Capítulos de Livros - FM/Outros

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A coleção de Livros e Capítulos de Livros reúne capítulos e resumos de obras produzidas por autores do complexo Hospital das Clínicas - Faculdade de Medicina da Universidade de São Paulo.


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Agora exibindo 1 - 20 de 598
  • bookPart 1 Citação(ões) na Scopus
    Combined screening for breast and gynecological cancers using mobile clinics: The barretos experience (Brazil)
    (2013) FILHO, A. L.; SILVA, T. B.; RODRIGUES, S.; HAIKEL, R. L. Jr.
    A mobile clinic is an effective method for providing cancer screening services for women and is particularly suited for women residing in remote locations with limited access to health care. The Barretos experience of providing such services to screen for breast and gynecological cancers is presented in this chapter. © Springer Science+Business Media New York 2013.
  • bookPart 1 Citação(ões) na Scopus
    Transcranial Magnetic Stimulation
    (2018) LEITE, J.; SIMIS, M.; CARVALHO, S.; FREGNI, F.
    More than 30 years have already passed since the seminal article of Baker et al., in which a transcranial magnetic stimulation (TMS) pulse over the motor cortex (MC) was successfully used to painlessly elicit a recordable electromyography response. Since then, multiple studies have been conducted exploring the underlying physiology of TMS effects, its potential uses in clinical settings, as well as safety. In this chapter, we provide an overview regarding the basic mechanisms of TMS, how it can be used as a tool to investigate human brain cortex physiology, how it can be used to alter cortical excitability, its safety concerns, and its use in clinical settings. © 2018 Elsevier Ltd. All rights reserved.
  • bookPart 30 Citação(ões) na Scopus
    Isolation of microglia and immune infiltrates from mouse and primate central nervous system
    (2017) GALATRO, T. F.; VAINCHTEIN, I. D.; BROUWER, N.; BODDEKE, E. W. G. M.; EGGEN, B. J. L.
    Microglia are the innate immune cells of the central nervous system (CNS) and play an important role in the maintenance of tissue homeostasis, providing neural support and neuroprotection. Microglia constantly survey their environment and quickly respond to homeostatic perturbations. Microglia are increasingly implicated in neuropathological and neurodegenerative conditions, such as Alzheimer’s disease, Parkinson’s disease, and glioma progression. Here, we describe a detailed isolation protocol for microglia and immune infiltrates, optimized for large amounts of post mortem tissue from human and rhesus macaque, as well as smaller tissue amounts from mouse brain and spinal cord, that yield a highly purified microglia population (up to 98 % purity). This acute isolation protocol is based on mechanical dissociation and a two-step density gradient purification, followed by fluorescence-activated cell sorting (FACS) to obtain pure microglia and immune infiltrate populations. © Springer Science+Business Media LLC 2017.
  • bookPart 0 Citação(ões) na Scopus
    Reactive oxygen species and redox signaling in breast cancer
    (2017) PANIS, C.; PIRES, B. R. B.; ANDRADE, A. C. De; SILVA, M. B.; VICTORINO, V. J.
    Breast cancer progression depends on host innate and adaptive immune responses. Despite the effect of immune system in tumor destruction, cancer cells may induce the immune cells to support tumor progression. During tumor-host interactions, both tumor and immune cells produce significant amounts of reactive species (RS). The imbalance resulting from RS production and its neutralization is called oxidative stress, and it modulates several cellular processes impacting breast cancer outcome. Two major sensors of these processes are the nuclear factor erythroid-derived 2-related factor 2 (NRF2) and NF-κB-related pathways. The transcriptional factor NF-?B has prooxidant capacity, while Nrf2 has neutralizing action. NF-κB is a regulator of innate immunity, and it induces RS production and inflammatory cytokines. Furthermore, high level of NF-κB is found for breast cancer, and its downstream signaling has been implicated in aggressive tumor features. The redox sensor NRF2 is activated under oxidative stress conditions and induces human antioxidant response element in order to control cellular homeostasis; however, it protects tumors against RS caused by chemotherapy leading to treatment resistance. This chapter raises the discussion regarding the redox mechanisms involved in breast cancer development driven by the activation of the Nrf2-NF-κB axis. © 2016 by Taylor & Francis Group, LLC.
  • bookPart 1 Citação(ões) na Scopus
    Comparative metagenomics
    (2018) THOMAS, A. Maltez; LIMA, F. Prata; MOURA, L. Maria Silva; SILVA, A. Maria da; DIAS-NETO, E.; SETUBAL, J. C.
    Thanks in large part to newer, better, and cheaper DNA sequencing technologies, an enormous number of metagenomic sequence datasets have been and continue to be generated, covering a huge variety of environmental niches, including several different human body sites. Comparing these metagenomes and identifying their commonalities and differences is a challenging task, due not only to the large amounts of data, but also because there are several methodological considerations that need to be taken into account to ensure an appropriate and sound comparison between datasets. In this chapter, we describe current techniques aimed at comparing metagenomes generated by 16S ribosomal RNA and shotgun DNA sequencing, emphasizing methodological issues that arise in these comparative studies. We provide a detailed case study to illustrate some of these techniques using data from the Human Microbiome Project comparing the microbial communities from ten buccal mucosa samples with ten tongue dorsum samples in terms of alpha diversity, beta diversity, and their taxonomic and functional profiles. © 2018, Springer Science+Business Media LLC.
  • bookPart 2 Citação(ões) na Scopus
    Caffeine and sport
    (2023) SAUNDERS, B.; COSTA, L. R. da; SOUZA, R. A. S. de; BARRETO, G.; MARTICORENA, F. M.
    Caffeine is a trimethylxanthine found in coffee and several other foods and beverages. Its stimulatory effects make it an interesting strategy to boost performance for athletic populations. Scientific evidence supports its efficacy to improve high-intensity endurance exercise, explosive and high-intensity efforts, resistance exercise, team sports and combat sports, though individual variation in the ergogenic response to caffeine exists. Supplementation can be taken in many forms including dissolved in water, via capsules, coffee, energy drinks and caffeinated gum; ingestion via capsules, dissolved in water or in caffeinated gum appear to be most effective. Variability in the exercise response following caffeine supplementation may be explained by genetic factors or habitual caffeine consumption. Caffeine is an excellent supplement for athletes looking to improve their exercise performance, though some consideration of side-effects and impact on sleep are warranted. © 2023
  • bookPart
    Medidas individuais contra o assédio moral: o que os estudantes ou residentes devem fazer quando sofrem abusos durante a época de treinamento?
    (2023) BELFIORE, Elio; JúNIOR, José Hélio Zen; TRUDA, Vanessa; SANTANA, Vanessa Souza; OLIVEIRA, Luciane Bastos Fernandes de; ORTONA, Concilia; VATTIMO, Edoardo Filippo de Queiroz
  • bookPart
    Medidas institucionais contra o assédio moral: o que supervisores e instituições devem fazer para combater o assédio moral no ambiente de ensino?
    (2023) VATTIMO, Edoardo Filippo de Queiroz; BELFIORE, Elio; JúNIOR, José Hélio Zen; TRUDA, Vanessa; SANTANA, Vanessa Souza; OLIVEIRA, Luciane Bastos Fernandes de; ORTONA, Concilia
  • bookPart
    A demografia do médico jovem brasileiro
    (2023) ORTONA, Concília; VATTIMO, Edoardo Filippo de Queiroz
  • bookPart
    Assédio moral entre estudantes de medicina e médicos residentes
    (2023) VATTIMO, Edoardo Filippo de Queiroz
  • bookPart
    (2023) VATTIMO, Edoardo Filippo de Queiroz; BELFIORE, Elio
  • bookPart
    Fisioterapia nas dores lombar e cervical
    (2023) SOUZA, Ingred Merllin Batista de; OLIVEIRA, Vinícius Cunha; BURKE, Thomaz Nogueira
  • bookPart
    Fisioterapia na osteoartrite
    (2023) ALMEIDA, Gabriel Peixoto Leão; JANUáRIO, Priscila de Oliveira
  • bookPart
    Manifestações reumatológicas na doença inflamatória intestinal
    (2015) SCHAINBERG, Cláudia Goldenstein
  • bookPart
    Autismo, transtornos do espectro do autismo
    (2015) CUNHA, Graccielle Rodrigues da; BORDINI, Daniela; CAETANO, Sheila Cavalcante
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  • bookPart
    Edema agudo de pulmão
    (2016) PINTO, Thiago Fernandes; THEODORO JUNIOR, Osmar
  • bookPart
    Atuação do assistente social
    (2016) DOMINGUES, Marisa Accioly Rodrigues; SILVA, Thaís Bento Lima da
  • bookPart
    Síndrome de Down
    (2021) MORIYAMA, Cristina Hamamura; MASSETTI, Thais