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bookPart 1 Citação(ões) na Scopus
Alzheimer’s Disease and the Volume of Hippocampal Subfields: Cluster Analysis Using Neuroimaging Data
(2019) PACHI, C. G. Fonseca; TORRALBO, L.; YAMAMOTO, J. F.
This study analyzes the presence of volumetric changes in subfields of the hippocampus using structural MR image from a large database of volunteers, selected and screened in three distinct groups of elderly subjects: Diagnosed with Alzheimer’s disease (AD) or cognitive impairment mild (MCI) and control group (CG). Images were processed using the FreeSurfer (FS) software methodology specifically developed for automated segmentation of these hippocampal subfields and this selected dataset has based a dissertation research about aging. Statistical tools allowed evaluating the presence of correlation between age and volumetric changes of hippocampal subfields in the advancing age. In addition, clustering analysis showed important similarities between the volumes of the hippocampal subfields of these subjects. © Springer Nature Switzerland AG 2019.
bookPart
Monitorização ambulatorial da pressão arterial
(2016) NOBRE, Fernando; JúNIOR, Décio Mion; LOPES, Paulo César; COLOMBO, Fernanda M. C.
bookPart
Pronto-socorro digital
(2023) NANBU, Danilo Yamamoto; COUTO, Thomaz Bittencourt
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Monitoramento e ajuste da proposta
(2023) OLIVEIRA, Paulo David Domingues de; DIAS, Renata Silva
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Inserção da proposta no sistema de cadastro para emendas
(2023) OLIVEIRA, Paulo David Domingues de; DIAS, Renata Silva
article 0 Citação(ões) na Scopus
Combined Anterior Cruciate Ligament and Anterolateral Ligament Reconstruction Using a Single Peroneus Longus Tendon Graft
(2024) SILVA, Andre Giardino Moreira da; MACEDO, Rodrigo Sousa; SOUZA, Michel Oliveira; GIGLIO, Pedro Nogueira; VIDEIRA, Livia Dau; GOBBI, Riccardo Gomes; SANTOS, Alexandre Leme Godoy dos; HELITO, Camilo Partezani
The peroneus longus tendon seems a viable graft option for knee ligament reconstructions, with adequate biomechanical properties and low morbidity after harvesting. The objective of this article is to describe a combined anterior cruciate ligament and anterolateral ligament reconstruction technique using a single peroneus longus tendon graft harvested from the infra malleolar region to ensure sufficient length.
article 0 Citação(ões) na Scopus
End-of-life experiences in the dying process: scoping and mixed-methods systematic review
(2023) SILVA, Tais Oliveira; RIBEIRO, Henrique Goncalves; MOREIRA-ALMEIDA, Alexander
ObjectivesTo identify the current state of understanding about end-of-life experiences (ELEs) and examine evidence concerning prevalence, the impact on the process of dying and the perceptions/explanations of patients, relatives and healthcare professionals (HCPs) with regard to ELEs. MethodsScoping review and mixed-methods systematic review (ScR and MMSR). Nine academic databases were searched for a screening of the available scientific literature (ScR). Articles reporting qualitative, quantitative or mixed-methods studies were selected (MMSR), the quality of which was assessed using the Joanna Briggs Institute (JBI) standardised critical appraisal tools. The quantitative data were synthesised in narrative form while a meta-aggregation approach was adopted for the qualitative results. ResultsThe ScR identified 115 reports, with 70.4% published after 2010, 55.6% from the USA and the most common terminology for ELE was deathbed visions (29%). The MMSR included 36 papers, describing 35 studies in various settings. The combination of quantitative and qualitative evidence indicated a greater prevalence of ELEs in samples of patients and HCPs compared with relatives. The most common ELEs were visions and dreams of the presence of deceased relatives/friends with references to making ready for a journey. The impact of ELEs was mainly positive, and there was a tendency to interpret them as spiritual experiences inherent to the process of dying. ConclusionsELEs are often reported by patients, relatives and HCPs and have a significant, generally positive impact on the process of dying. Guidelines for the furtherance of studies and clinical applications are discussed.
article 0 Citação(ões) na Scopus
Epidemiological and Clinical Characteristics of Young Patients With Breast Cancer in Brazil: A Retrospective Study
(2023) CORREA, Daniela B.; ARAUJO, Guilhermino C.; ALVARENGA, Bruno H.; RODRIGUES, Angelica N.
PURPOSE Understanding the epidemiological profile of young patients with breast cancer (BC) is crucial for devising effective control strategies. However, data on Brazilian patients with BC, particularly concerning the association with pathogenic germline mutations, are limited. This retrospective cross-sectional study seeks to shed light on the epidemiological and genetic profiles of young patients with BC in Brazil, with a specific focus on the correlation between germline mutations and clinical outcomes. METHODS We analyzed medical records from two institutions in Minas Gerais, Brazil, focusing on young patients with BC diagnosed from January 2012 to December 2020. The collected variables included sociodemographic profile, tumor characteristics, mutational status, follow-up duration, and time from diagnosis to death. RESULTS The findings highlight high rates of genetic mutations, more aggressive tumor characteristics, and the necessity for more radical surgical interventions in patients with mutations. CONCLUSION In general, young patients with BC in Brazil present an unfavorable prognosis, emphasizing the need for early diagnosis and personalized treatment strategies.
article 0 Citação(ões) na Scopus
Photobiomodulation Associated With Conservative Treatment for Achilles Tendon Rupture: A Double-Blind, Superiority, Randomized Controlled Trial
(2022) OLIVEIRA, P. R. de; ARREBOLA, L. S.; STéFANI, K. C.; PINFILDI, C. E.
Objective: To investigate the effects of photobiomodulation on Achilles tendon rupture (ATR) treated conservatively. Design: Prospective, patient- and assessor-blinded, parallel, randomized controlled trial. Setting: Patients with acute ATR treated conservatively. Participants: Thirty-four male individuals with acute unilateral ATR treated conservatively (N=34), equally divided in 2 groups: photobiomodulation group (PBMG) and sham group, with mean age of 45.5±9.47 and 48.7±8.38 years, respectively. Intervention: All participants underwent through an immobilization period, followed by rehabilitation sessions (2 d/wk for 12 weeks) comprising strengthening, range of motion, and balance/weightbearing exercises. In PBMG, the tendon was irradiated with a photobiomodulation cluster (1 904 nm/50 mW infrared laser, 4 858 nm/50 mW infrared diodes, and 4 658 nm/40 mW red diodes; power density of 105 mW/cm2 per cluster area) during the immobilization period (2 d/wk for 8 weeks) and the sham group received a simulation of the procedure with no irradiation. Outcomes were assessed at the removal of the immobilization 12 and 16 weeks after tendon rupture. Main Outcome Measures: Primary outcome was the Achilles Tendon Rupture Score. Secondary outcomes included Numerical Pain Rating Scale at rest and during effort, plantar flexor strength, and ankle range of motion. Results: Both groups demonstrated an increase in the Achilles Tendon Rupture Score and improvements in range of motion, plantar flexor strength, and pain. There were no significant differences in outcomes between the 2 groups (P>.05) except in pain during walking, which was significantly lower in the PBMG in week 12 (P<.01, effect size=0.56) and week 16 (P<.01, effect size=0.55). Conclusion: Photobiomodulation associated with conservative treatment is not superior to conservative treatment alone for improving function in patients with acute ATR.