CLAUDIO LYOITI HASHIMOTO
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico
25 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 25
- FECAL OCCULT BLOOD: A COMPARISON OF CHEMICAL AND IMMUNOCHEMICAL TESTS(2018) BORGES, Luana Vilarinho; MATTAR, Rejane; SILVA, Joyce Matie Kinoshita da; SILVA, Ana Luiza Werneck da; CARRILHO, Flair José; HASHIMOTO, Cláudio LyoitiABSTRACT BACKGROUND: Colorectal bleeding is a warning sign that may be identified by fecal occult blood testing. A positive fecal occult blood test result requires a subsequent colonoscopy, a costly and invasive examination. Therefore, the use of diagnostic tests with optimal sensitivity and specificity is warranted. In this study, we evaluated four different fecal occult blood tests in 176 patients undergoing colonoscopy and compared their results. OBJECTIVE: To assess the sensitivity, specificity and predictive values of chemical and immunochemical fecal occult blood tests in patients undergoing colonoscopy and to evaluate the degree of concordance between the tests and colonoscopy. METHODS: Patients with indications for colonoscopy also underwent fecal occult blood testing by chemical (toluidine test) and immunochemical methods, employing three commercially available kits. Based on the endoscopic findings, the colonoscopy was rated as positive or negative for colorectal bleeding. The degree of concordance between the fecal occult blood tests and the colonoscopy was evaluated by the kappa index. RESULTS: Forty-four (25%) colonoscopies were categorized as positive for colorectal bleeding. The toluidine test presented lower concordance than the immunochemical tests, which showed moderate concordance with the colonoscopy. The toluidine test had the least sensitivity, specificity, and positive and negative predictive values. CONCLUSION: The immunochemical fecal occult blood tests showed greater sensitivity, specificity and predictive values in detecting colorectal bleeding. The immunochemical tests had superior indexes of agreement with colonoscopy compared to the toluidine test.
bookPart Doença do Repluxo Gastroesofágico(2016) LUGãO, Renata dos Santos; MORAES FILHO, Joaquim Prado Pinto de; HASHIMOTO, Cláudio LyoitibookPart Tumores do Estômago(2016) FERREIRA, Ricardo Paes Barreto; EISIG, Jaime Natan; MEDEIROS, Vitor de Souza; HASHIMOTO, Cláudio Lyoiti- WHAT ARE THE MOST IMPORTANT FACTORS REGARDING ACCEPTANCE TO THE COLONOSCOPY?: Study of related tolerance parameters(2013) USSUI, Vivian Mayumi; SILVA, Ana Luiza Werneck da; BORGES, Luana Vilarinho; SILVA, José Guilherme Nogueira da; ZEITUNE, José Murilo Robilotta; HASHIMOTO, Cláudio LyoitiContext Colonoscopy plays an indubitable role in the setting of clinical practice, however, it is an invasive exam; complex, lengthy, embarrassing, not devoid of risks and discomfort that yields fear and anxiety in the majority of patients. In a new era of rising competition between health institutions, where the quality of health care and client satisfaction are praised, studies regarding tolerance-related colonoscopy issues yield great potential to be explored. In the present study, tolerance is defined as willingness to repeat the exam. Objectives Evaluate information associated to bowel preparation, the exam itself and post-examination period that might interfere with the tolerance to the colonoscopy. Methods Analysis of the tolerance to the colonoscopy at three stages (pre, post, and during) through a checklist: patient's questionnaire and a medical assessment form were used. Results In this present study, 91.2% of 373 patients exhibited positive tolerance to the colonoscopy. Aspects related to a negative level of tolerance were patient gender (12.9% of women versus 3.2% of men would not repeat the exam), age extremes (less than 20 years and greater than 80 years of age), and abdominal pain, both during the bowel preparation and after the procedure. Conclusions Gender, age, patient cooperation and abdominal pain were the decisive components regarding tolerance to the colonoscopy. Notably, in two phases of the exam, the abdominal pain was the most important feature associated to a lessened tolerance.
- Prevalence of dysplasia and colorectal cancer in Ulcerative Colitis patients from a referral center in Latin America(2021) JUNIOR, R. S. F.; CARVALHO, M. F.; SILVA, J. C.; BARROS, L. L.; AZEVEDO, M. F. C.; CARLOS, A. D. S.; OBA, J.; HASHIMOTO, C. L.; CANCADO, E. L. R.; DAMIAO, A. O. M. C.; SIPAHI, A. M.
conferenceObject RANDOMIZED CONTROLLED TRIAL COMPARING UNDERWATER AND CONVENTIONAL ENDOSCOPIC MUCOSAL RESECTION FOR NON-PEDUNCULATED COLORECTAL LESIONS(2022) LENZ, Luciano H.; MARTINS, Bruno; PAULO, Gustavo A. De; KAWAGUTI, Fabio S.; BABA, Elisa R.; UEMURA, Ricardo S.; GUSMON, Carla C.; GEIGER, Sebastian N.; MOURA, Renata N.; PENNACCHI, Caterina; LIMA, Marcelo S. De; SAFATLE-RIBEIRO, Adriana V.; HASHIMOTO, Claudio L.; RIBEIRO, Ulysses; MALUF-FILHO, Fauze- Bowel preparation for performing a colonoscopy: prospective randomized comparison study between a low-volume solution of polyethylene glycol and bisacodyl versus bisacodyl and a mannitol solution(2012) VIEIRA, Manoel Carlos; HASHIMOTO, Claudio Lyoiti; CARRILHO, Flair JoséCONTEXT: Colonoscopy is currently the gold standard method to examine the colon, the rectum and the terminal ileum. In order to perform the colonoscopy, it is necessary to clean the bowel and use medications that are generally poorly tolerated by the patients. OBJECTIVE: Compare the tolerability, acceptability, safety and efficacy of two solutions used for intestinal preparation for a colonoscopy. METHODS: One hundred patients matched for sex and age were prospective randomized into two groups. Polyethylene glycol group received bisacodyl 10 mg plus 1 L of polyethylene glycol the night before and 1 L on the day of the exam. Mannitol group received bisacodyl 20 mg the day before and 1 L of a 10% mannitol solution on the day of the exam. The diet was the same for both groups. Tolerability and acceptability were measured using previously validated questionnaires. In terms of safety, variations in vital signs before and after the preparation were recorded, in addition to any complications. The quality of the preparation was graded based on the Boston and Ottawa scales. RESULTS: Ninety-six percent (96%) completed the study. As for tolerability, the mannitol preparation group exhibited a significantly higher frequency of nausea, vomiting, abdominal pain, and abdominal distension than polyethylene glycol group (P < 0.05). Acceptability was significantly better in polyethylene glycol group. The polyethylene glycol solution has also previously been shown to be safer than mannitol. No difference was observed in the quality of the preparation between the two preparation methods. CONCLUSIONS: The following conclusions can be made: polyethylene glycol solution had higher tolerability, acceptability, and safety than the mannitol and should be used instead of mannitol. Both preparation solutions have similar efficacy.
conferenceObject Underwater Endoscopic Mucosal Resection for Non-Pendulated Colorectal Lesions. Is the Distal Cap Really Necessary?(2017) LENZ, Luciano; OLIVEIRA, Joel; MENDONCA, Ernesto Q.; GONZALEZ, Esteban H.; MINATA, Mauricio K.; PAULO, Gustavo A. de; GEIGER, Sebastian N.; SORBELLO, Mauricio; LIMA, Marcelo A.; KAWAGUTI, Fabio S.; MARTINS, Bruno da Costa; BABA, Elisa R.; SAFATLE-RIBEIRO, Adriana V.; GUSMON, Carla C.; PENNACCHI, Caterina; UEMURA, Ricardo S.; TELLIAN, Alexandre; ROLIM, Fausto; HASHIMOTO, Claudio; RIBEIRO, Ulysses; MALUF-FILHO, FauzeconferenceObject COMPARISON OF TWO CUT-OFF VALUES OF THE FECAL IMMUNOCHEMICAL TEST DURING AN ORGANIZED COLORECTAL CANCER SCREENING(2019) SAFATLE-RIBEIRO, Adriana V.; SORBELLO, Mauricio P.; PFUETZENREITER, Vinicius; BASTOS, Victor R.; COHEN, Diane D.; SOUZA, Afonso H. Silva e; HASHIMOTO, Claudio L.; FRANCO, Joel L.; GOMES, Jackeline O.; ALVES, Venancio A.; CECCONELLO, Ivan; NAHAS, Sergio C.; ELUF NETO, Jose; RIBEIRO, UlyssesbookPart Tumores do Esôfago(2016) HASHIMOTO, Cláudio Lyoiti; ROSSINI, Alessandra Rita Asayama Lopes; OTTONI, Leandro Ferreira; MORAES FILHO, Joaquim Prado Pinto de
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