LUCAS DE PADUA GOMES DE FARIAS
Projetos de Pesquisa
Unidades Organizacionais
Instituto de Radiologia, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/44 - Laboratório de Ressonância Magnética em Neurorradiologia, Hospital das Clínicas, Faculdade de Medicina
LIM/44 - Laboratório de Ressonância Magnética em Neurorradiologia, Hospital das Clínicas, Faculdade de Medicina
15 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 15
- Airway-Invasive Aspergillosis: Acute Tracheobronchitis(2022) FARIAS, Lucas de Padua Gomes de; SAWAMURA, Marcio Valente Yamada
- The role of the radiologist in the assessment of thoracic changes after radiotherapy(2021) ANDO, Sabrina de Mello; FONSECA, Eduardo Kaiser Ururahy Nunes; FRASSEI, Julliana dos Santos; FARIAS, Lucas de Pádua Gomes de; NEVES, Yuri Costa Sarno; CHATE, Rodrigo Caruso; SAWAMURA, Márcio Valente YamadaAbstract Radiotherapy plays a central role in the palliative and curative treatment of neoplasms of the chest wall or intrathoracic structures. However, despite technical advances, radiotherapy can alter previously normal organs and tissues, those alterations presenting as various types of imaging findings. Post-radiation alterations must be promptly recognized by radiologists, in order to avoid confusion between complications of radiotherapy and the recurrence of a tumor. This pictorial essay aims to illustrate different thoracic changes after radiotherapy.
- Swyer-James-MacLeod Syndrome: The Hyperlucent Lung(2020) FARIAS, Lucas De Padua Gomes De; FONSECA, Eduardo Kaiser Ururahy Nunes; CHATE, Rodrigo Caruso; SAWAMURA, Marcio Valente Yamada
- COVID-19 pneumonia and the reversed halo sign(2020) FARIAS, Lucas de Padua Gomes de; STRABELLI, Daniel Giunchetti; SAWAMURA, Marcio Valente Yamada
- Thoracic tomographic manifestations in symptomatic respiratory patients with COVID-19(2020) FARIAS, Lucas de Pádua Gomes de; STRABELLI, Daniel Giunchetti; FONSECA, Eduardo Kaiser Ururahy Nunes; LOUREIRO, Bruna Melo Coelho; NOMURA, Cesar Higa; SAWAMURA, Márcio Valente YamadaAbstract China was the epicenter for the novel coronavirus disease (COVID-19), which quickly spread to other Asian countries and later to Western countries; subsequently, COVID-19 was categorized as a pandemic by the World Health Organization. Diagnosis primarily depends on viral detection in respiratory samples; however, available kits are limited, lack high sensitivity, and have a long turnaround time for providing results. In this scenario, computed tomography has emerged as an efficient and available high-sensitivity method, allowing radiologists to readily recognize findings related to COVID-19. The objective of this article is to demonstrate the main tomographic findings in symptomatic respiratory patients with COVID-19 to assist medical professionals during this critical moment.
- The Role of Radiomics in Rectal Cancer(2023) MIRANDA, Joao; HORVAT, Natally; ARAUJO-FILHO, Jose A. B.; ALBUQUERQUE, Kamila S. S.; CHARBEL, Charlotte; TRINDADE, Bruno M. C.; CARDOSO, Daniel L. L.; FARIAS, Lucas de Padua Gomes de; CHAKRABORTY, Jayasree; NOMURA, Cesar HigaPurposeRadiomics is a promising method for advancing imaging assessment in rectal cancer. This review aims to describe the emerging role of radiomics in the imaging assessment of rectal cancer, including various applications of radiomics based on CT, MRI, or PET/CT.MethodsWe conducted a literature review to highlight the progress of radiomic research to date and the challenges that need to be addressed before radiomics can be implemented clinically.ResultsThe results suggest that radiomics has the potential to provide valuable information for clinical decision-making in rectal cancer. However, there are still challenges in terms of standardization of imaging protocols, feature extraction, and validation of radiomic models. Despite these challenges, radiomics holds great promise for personalized medicine in rectal cancer, with the potential to improve diagnosis, prognosis, and treatment planning. Further research is needed to validate the clinical utility of radiomics and to establish its role in routine clinical practice.ConclusionOverall, radiomics has emerged as a powerful tool for improving the imaging assessment of rectal cancer, and its potential benefits should not be underestimated.
- COVID-19 on resonance magnetic: an incidental but important finding in times of pandemic(2020) GARCIA, Jose Vitor Rassi; FONSECA, Eduardo Kaiser Ururahy Nunes; CHATE, Rodrigo Caruso; STRABELLI, Daniel Giunchetti; FARIAS, Lucas de Padua Gomes de; LOUREIRO, Bruna Melo Coelho; FERREIRA, Lorena Carneiro; SAWAMURA, Marcio Valente Yamada
- Lung Lesion Burden found on Chest CT as a Prognostic Marker in Hospitalized Patients with High Clinical Suspicion of COVID-19 Pneumonia: a Brazil ian experience(2021) FONSECA, Eduardo Kaiser Ururahy Nunes; ASSUNCAO JUNIOR, Antonildes Nascimento; ARAUJO-FILHO, Jose De Arimateia Batista; FERREIRA, Lorena Carneiro; LOUREIRO, Bruna Melo Coelho; STRABELLI, Daniel Giunchetti; FARIAS, Lucas de Padua Gomes de; CHATE, Rodrigo Caruso; CERRI, Giovanni Guido; SAWAMURA, Marcio Valente Yamada; NOMURA, Cesar HigaOBJECTIVE: To investigate the relationship between lung lesion burden (LLB) found on chest computed tomography (CT) and 30-day mortality in hospitalized patients with high clinical suspicion of coronavirus disease 2019 (COVID-19), accounting for tomographic dynamic changes. METHODS: Patients hospitalized with high clinical suspicion of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in a dedicated and reference hospital for COVID-19, having undergone at least one RTPCR test, regardless of the result, and with one CT compatible with COVID-19, were retrospectively studied. Clinical and laboratory data upon admission were assessed, and LLB found on CT was semi-quantitatively evaluated through visual analysis. The primary outcome was 30-day mortality after admission. Secondary outcomes, including the intensive care unit (ICU) admission, mechanical ventilation used, and length of stay RESULTS: A total of 457 patients with a mean age of 57 +/- 15 years were included. Among these, 58% presented with positive RT-PCR result for COVID-19. The median time from symptom onset to RT-PCR was 8 days [interquartile range 6-11 days]. An initial LLB of X50% using CT was found in 201 patients (44%), which was associated with an increased crude at 30-day mortality (31% vs. 15% in patients with LLB of <50%, p<0.001). An LLB of X50% was also associated with an increase in the ICU admission, the need for mechanical ventilation, and a prolonged LOS after adjusting for baseline covariates and accounting for the CT findings as a time-varying covariate; hence, patients with an LLB of X50% remained at a higher risk at 30-day mortality (adjusted hazard ratio 2.17, 95% confidence interval 1.47-3.18, p<0.001). CONCLUSION: Even after accounting for dynamic CT changes in patients with both clinical and imaging findings consistent with COVID-19, an LLB of X50% might be associated with a higher risk of mortality.
- Rasmussen aneurysm(2021) FARIAS, L. P. G. de; FONSECA, E. K. U. N.; CHATE, R. C.; SAWAMURA, M. V. Y.
- Evaluation of the RSNA and CORADS classifications for COVID-19 on chest computed tomography in the Brazilian population(2021) FONSECA, Eduardo Kaiser Ururahy Nunes; LOUREIRO, Bruna Melo Coelho; STRABELLI, Daniel Giunchetti; FARIAS, Lucas de Padua Gomes de; GARCIA, Jose Vitor Rassi; GAMA, Victor Arcanjo Almeida; FERREIRA, Lorena Carneiro; CHATE, Rodrigo Caruso; ASSUNCAO JUNIOR, Antonildes Nascimento; SAWAMURA, Marcio Valente Yamada; NOMURA, Cesar HigaOBJECTIVE: To determine the correlation between the two tomographic classifications for coronavirus disease (COVID-19), COVID-19 Reporting and Data System (CORADS) and Radiological Society of North America Expert Consensus Statement on Reporting Chest Computed Tomography (CT) Findings Related to COVID-19 (RSNA), in the Brazilian population and to assess the agreement between reviewers with different experience levels. METHODS: Chest CT images of patients with reverse transcriptase-polymerase chain reaction (RT-PCR)-positive COVID-19 were categorized according to the CORADS and RSNA classifications by radiologists with different levels of experience and who were initially unaware of the RT-PCR results. The inter- and intra-observer concordances for each of the classifications were calculated, as were the concordances between classifications. RESULTS: A total of 100 patients were included in this study. The RSNA classification showed an almost perfect inter-observer agreement between reviewers with similar experience levels, with a kappa coefficient of 0.892 (95% confidence interval [CI], 0.788-0.995). CORADS showed substantial agreement among reviewers with similar experience levels, with a kappa coefficient of 0.642 (95% CI, 0.491-0.793). There was inter-observer variation when comparing less experienced reviewers with more experienced reviewers, with the highest kappa coefficient of 0.396 (95% CI, 0.255-0.588). There was a significant correlation between both classifications, with a Kendall coefficient of 0.899 (p<0.001) and substantial intra-observer agreement for both classifications. CONCLUSION: The RSNA and CORADS classifications showed excellent inter-observer agreement for reviewers with the same level of experience, although the agreement between less experience reviewers and the reviewer with the most experience was only reasonable. Combined analysis of both classifications with the first RT-PCR results did not reveal any false-negative results for detecting COVID-19 in patients.