YOSHITAKA NAKASHIMA
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina
LIM/33 - Laboratório de Oftalmologia, Hospital das Clínicas, Faculdade de Medicina
LIM/33 - Laboratório de Oftalmologia, Hospital das Clínicas, Faculdade de Medicina
11 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 11
bookPart Urgências e emergências oftalmológicas(2013) ZAMBON, Felipi; NAKASHIMA, Yoshitaka- Unusual macular thickness in Alport syndrome: case report(2012) IGAMI, Thais Z.; LAVEZZO, Marcelo M.; FERRAZ, Daniel A.; TAKAHASHI, Walter Y.; NAKASHIMA, YoshitakaThis case report describes the presence of bilateral macular atrophy in a patient with Alport syndrome and compares this finding with literature. At fundoscopy, there was a discrete circumscribed macular thinning showing intense retinal pigment epithelium color and the presence of whitish circular retinal lesions (""dots"" and ""flecks"") at nasal mid periphery of both eyes. Optical coherence tomography showed bilateral partial atrophy of the neurosensory retina in the macula, with a greater extent in the temporal region. This case describes a rare ophthalmological finding in Alport syndrome and important to be recognized for a precise diagnosis as well as for determining visual prognosis.
- The effect of laser pan-retinal photocoagulation with or without intravitreal bevacizumab injections on the OCT-measured macular choroidal thickness of eyes with proliferative diabetic retinopathy(2017) PRETI, Rony C.; MUTTI, Anibal; FERRAZ, Daniel A.; ZACHARIAS, Leandro C.; NAKASHIMA, Yoshitaka; TAKAHASHI, Walter Y.; MONTEIRO, Mario L. R.OBJECTIVES: To investigate the effect of laser pan-retinal photocoagulation with or without intravitreal bevacizumab injections on macular choroidal thickness parameters in eyes with high-risk proliferative diabetic retinopathy. METHODS: High-risk proliferative diabetic retinopathy patients undergoing laser treatment were prospectively enrolled in this study. One eye was randomly selected for laser treatment combined with bevacizumab injections, study group, whereas the corresponding eye was subjected to laser treatment alone, control group. Spectral-domain optical coherence tomography with enhanced depth imaging was used to measure the macular choroidal thickness prior to and 1 month after treatment. Measurements in both groups were compared. Clinicaltrials. gov: NCT01389505. RESULTS: Nineteen patients (38 eyes) with a mean +/- standard deviation age of 53.4 +/- 9.3 years were evaluated, and choroidal thickness measurements for 15 patients were used for comparison. The greatest measurement before treatment was the subfoveal choroidal thickness (341.68 +/- 67.66 mm and 345.79 +/- 83.66 mm for the study and control groups, respectively). No significant difference between groups was found in terms of macular choroidal thickness measurements at baseline or after treatment. However, within-group comparisons revealed a significant increase in choroidal thickness parameters in 10 measurements in the study group and in only 5 temporal measurements in the control group when 1-month follow-up measurements were compared to baseline values. CONCLUSIONS: The macular choroidal thickness does not appear to be significantly influenced by laser treatment alone but increases significantly when associated with bevacizumab injections in patients with proliferative diabetic retinopathy and macular edema. Because bevacizumab injections reduce short-term laser pan-retinal photocoagulation-induced macular edema, our findings suggest that the choroid participates in its pathogenesis.
conferenceObject Explanted Scleral Buckle, a retrospective study(2015) OLIVEIRA, Luiza Manhezi de Freitas; GIOIA, Thais Sabota Romano Di; ROSA, Valeria Teixeira Alves; ALMEIDA, Joao Nobrega de Nobrega de; ROSSI, Flavia; KATO, Juliana Mika; FERREIRA, Bruno Fortaleza de Aquino; TANAKA, Tatiana; NAKASHIMA, Yoshitaka; PIMENTEL, Sergio Luis Gianotti- Effect of a Single Intravitreal Bevacizumab Injection on Contrast Sensitivity and Macular Thickness in Eyes with Macular Edema from Central Retinal Vein Occlusion: A Prospective, Nonrandomized, Three-Month Follow-Up Study(2014) PRETI, Rony C.; RAMIREZ, Lisa M. V.; PIMENTEL, Sergio L. G.; NAKASHIMA, Yoshitaka; MACHADO, Cleide G.; PELAYES, David E.; MONTEIRO, Mario L. R.; TAKAHASHI, Walter Y.Purpose: To evaluate the results of intravitreal bevacizumab (IVB) injection on contrast sensitivity (CS), best-corrected visual acuity (BCVA), foveal thickness (FT) and macular volume (MV) as measured by optical coherence tomography in patients with macular edema (ME) from central retinal vein occlusion (CRVO). Methods: Sixteen consecutive eyes from 16 patients with ME from unilateral CRVO were treated with a single IVB injection. The CS, BCVA, FT and MV measurements were obtained before the treatment and 1 and 3 months after the injection. Results: CS demonstrated significant improvement at all spatial frequencies - 1.5, 3, 6, 12 and 18 cycles per degree (cpd) - 1 month after the injection and at 6 cpd at the 3-month follow-up. The mean BCVA measurements in log of the minimum angle of resolution (logMAR) units improved from 1.03 at baseline to 0.83 logMAR 1 month after the injection, but worsened to 0.97 logMAR at 3 months. The mean baseline FT +/- standard deviation (SD; 620.06 +/- 177.60 mu m) was reduced significantly 1 month (270.93 +/- 74.17 mu m) and 3 months (535.56 +/- 222.33 mu m) after the treatment. The mean baseline MV +/- SD (12,765.56 +/- 3,769.70 mm 3) was reduced significantly at the 1-month (8,324.93 +/- 932.04 mm(3)) and 3-month (11,319.44 +/- 3,044.74 mm(3)) follow-up visits. Conclusions: IVB improved CS, BCVA, FT and MV within a short time period (1 month). Although VA was not improved at 3 months, improvements were observed for CS, FT and MV, which indicates that, despite ME recurrence, there still was some benefit to visual function. (C) 2014 S. Karger AG, Basel
conferenceObject Etiology and susceptibility pattern of isolates in endophthalmitis over a 5-year period(2015) KATO, Juliana Mika; OLIVEIRA, Maura Salaroli de; LEVIN, Anna Sara; ALMEIDA, Joao Nobrega de Nobrega de; ROSSI, Flavia; OLIVEIRA, Luiza Manhezi de Freitas; RUPPERT, Aline Domingos Pinto; TANAKA, Tatiana; NAKASHIMA, Yoshitaka; PIMENTEL, Sergio Luis GianottibookPart Afecções Oculares no Departamento de Emergência(2016) ZAMBON, Felipi; NAKASHIMA, Yoshitaka- VITRECTOMY for STELLATE NONHEREDITARY IDIOPATHIC FOVEOMACULAR RETINOSCHISIS ASSOCIATED with OUTER RETINAL LAYER DEFECT(2022) MORAES, B. R. M.; FERREIRA, B. F. A.; NOGUEIRA, T. M.; NAKASHIMA, Y.; JúNIOR, H. P. P.; SOUZA, E. C.Purpose:To describe a case of stellate nonhereditary idiopathic foveomacular retinoschisis associated with outer retinal layer defect treated with pars plana vitrectomy, internal limiting membrane removal, and C3F8 tamponade.Methods:Spectral-domain optical coherence tomography (Heidelberg Engineering, Heidelberg, Germany) scans of a 46-year-old woman with unilateral stellate nonhereditary idiopathic foveomacular retinoschisis were acquired at baseline and 1, 3, 6, and 12 months after surgery.Results:Pars plana vitrectomy was performed after phacoemulsification. The vitreous was circumcised, and the internal limiting membrane was removed with a Tano brush, releasing tangential forces. The patient experienced progressive recovery of the outer retinal layers and improvement of visual acuity during follow-up.Conclusion:Stellate nonhereditary idiopathic foveomacular retinoschisis may be associated with outer retinal layer defect and severe vision loss. Pars plana vitrectomy with internal limiting membrane removal and C3F8 infusion seems to be a safe and feasible treatment in such cases, with potentially good anatomical and functional outcome. © 2022 Lippincott Williams and Wilkins. All rights reserved.
conferenceObject The use of pediatric blood culture bottles in the diagnosis of acute postoperative endophthalmitis(2015) TANAKA, Tatiana; ALMEIDA, Joao Nobrega de; GIOIA, Thais Sabota Romano Di; ROSSI, Flavia; KATO, Juliana Mika; FERREIRA, Bruno Fortaleza de Aquino; RUPPERT, Aline Domingos Pinto; NAKASHIMA, Yoshitaka; PIMENTEL, Sergio Luis Gianotti; YAMAMOTO, Joyce H.bookPart Afecções oculares no departamento de emergência(2017) ZAMBON, Felipi; NAKASHIMA, Yoshitaka