FILOMENA MARIKO AMARO TAKIGUTI
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina
2 resultados
Resultados de Busca
Agora exibindo 1 - 2 de 2
bookPart Arnaldo(2017) TAKIGUTI, Filomena Mariko Amaro; SANTOS, Itamar de Souza; VALLADãO JúNIOR, José Benedito Ramos; MARTENS, Lilian Bentivegna; MINOTTI, Tamara Cristina; MANDIA, Tatiana Millaarticle 20 Citação(ões) na Scopus Micoses superficiais e os elementos da resposta imune*(2011) CRIADO, Paulo Ricardo; OLIVEIRA, Cristiane Beatriz de; DANTAS, Katia Cristina; TAKIGUTI, Filomena Amaro; BENINI, Luciana Vasconcellos; VASCONCELLOS, CidiaSuperficial mycoses are prevalent worldwide. They are often caused by dermatophytes and restricted to the stratum corneum. The host's immune response against infections caused by dermatophytes basically depends on the host's defense against metabolites of the fungi, virulence of the infecting strain or species and anatomical site of the infection. We will review some of the factors of the host's immune defense that influence the efficacy of the immune response. We will particularly review the role of pattern recognition receptors (PRRs), such as toll-like receptors or lectin receptors (DCSIGN and Dectin 2), which participate in the innate immune response, bringing specificity to the immune response and setting its pattern. The predominance of a cellular or humoral immune response determines the clinical manifestations and the prognosis of the infection, leading to healing or chronicity. Keywords: Allergy and immunology; Fungi; Inflammation mediators; Integumentary system