MARCELO JOSE ABDUCH ADAS BRAñAS
Projetos de Pesquisa
Unidades Organizacionais
Instituto de Psiquiatria, Hospital das Clínicas, Faculdade de Medicina
LIM/23 - Laboratório de Psicopatologia e Terapêutica Psiquiátrica, Hospital das Clínicas, Faculdade de Medicina
LIM/23 - Laboratório de Psicopatologia e Terapêutica Psiquiátrica, Hospital das Clínicas, Faculdade de Medicina
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bookPart Transtornos de personalidade(2019) BRAñAS, Marcelo José Abduch Adas; CROCI, Marcos Signoretti; MARTINHO JUNIOR, Eduardo- Neuroimaging Studies of Nonsuicidal Self-Injury in Youth: A Systematic Review(2021) BRANAS, Marcelo J. A. A.; CROCI, Marcos S.; SALTO, Ana Beatriz Ravagnani; DORETTO, Victoria F.; MARTINHO, Eduardo; MACEDO, Marcos; MIGUEL, Euripedes C.; ROEVER, Leonardo; PAN, Pedro M.Nonsuicidal self-injury (NSSI) is prevalent and affects mainly the youth population. It is prospectively associated with suicide attempts, making it a target for suicide prevention. Recently, several studies have investigated neural pathways of NSSI using neuroimaging. However, there is a lack of systematized appraisal of these findings. This systematic review aims to identify and summarize the main neuroimaging findings of NSSI in youth. We followed PRISMA statement guidelines and searched MEDLINE, APA PsycInfo, and Google Scholar databases for neuroimaging studies, irrespective of imaging modality, specifically investigating NSSI in samples with a mean age of up to 25 years old. Quality assessment was made using the Newcastle-Ottawa and Joanna Briggs Institute scales. The initial search retrieved 3030 articles; 21 met inclusion criteria, with a total of 938 subjects. Eighteen studies employed functional neuroimaging techniques such as resting-state and task-based fMRI (emotional, interpersonal exposure/social exclusion, pain, reward, and cognitive processing paradigms). Three studies reported on structural MRI. An association of NSSI behavior and altered emotional processing in cortico-limbic neurocircuitry was commonly reported. Additionally, alterations in potential circuits involving pain, reward, interpersonal, self-processing, and executive function control processes were identified. NSSI has complex and diverse neural underpinnings. Future longitudinal studies are needed to understand its developmental aspects better.
bookPart A entrevista clínica psiquiátrica(2019) MARCHETTI, Renato Luiz; GALLUCCI NETO, José; CROCI, Marcos Signoretti; BRAñAS, Marcelo José Abduch AdasbookPart Tratamento dos transtornos de personalidade(2021) BRANãS, Marcelo José Abduch Adas; CROCI, Marcos Signoretti; RIBEIRO, João Cronemberger Sá; JR, Eduardo Martinho- The Relationship Between Self-Harm and Suicide in Adolescents and Young Adults(2022) BRANAS, Marcelo J. A. A.; CROCI, Marcos S.; MURRAY, Grace E.; CHOI-KAIN, Lois W.Nonsuicidal self-injury is a common development among adolescents that varies in severity, frequency, and asso-ciated psychiatric vulnerability. A key challenge is to understand how clini-cians can identify those at greater risk, specifically for transition to suicide attempts. Shared functions (eg, to es-cape negative emotions) and risk fac-tors in selected domains (eg, exposure to self-harm in others, impulsivity, can-nabis and other drug use, diminished social connections, and history of bul-lying) between self-injury and suicide can explain this association and guide interventions. General guidelines for nonsuicidal self-injury and comorbid suicidal behavior in youth include mapping its predisposing factors and psychological functions, assessing se-verity and acute risk, and elucidating context (eg, interpersonal stressors). No medication has proven effective in reducing self-harm. Outpatient psy-chological treatment is the first option to address relevant emotional, behav-ioral, and interpersonal vulnerabilities, and evidence-based treatments can be effective (eg, dialectical behavior ther-apy, mentalization-based treatment, and cognitive-behavioral therapy). [Psychiatr Ann. 2022;52(8):311-317.]
bookPart Terapia comportamental dealética(2021) DORNELLES, Vinícius Guimarães; BRANãS, Marcelo José Abduch Adas; CROCI, Marcos Signoretti; JR, Eduardo Martinho- Longitudinal Description and Prediction of Smoking Among Borderline Patients: An 18 Year Follow-Up Study(2023) BRANAS, Marcelo J. A. A.; FRANKENBURG, Frances R.; TEMES, Christina M.; FITZMAURICE, Garrett M.; ZANARINI, Mary C.Objective: The objectives of this study were (1) to compare smoking between recovered and non-recovered patients with borderline personality disorder (BPD) over the course of 18 years and (2) to assess baseline predictors of tobacco use in patients with BPD. Methods: A total of 264 borderline patients were interviewed concerning their smoking history beginning at the 6-year follow-up wave in a longitudinal study of the course of BPD (McLean Study of Adult Development) and re -interviewed at 2-year intervals over the next 18 years. Initial data collection of the larger study happened between June 1992 and December 1995, and the DSM-III-R and the Revised Diagnostic Interview for Borderlines (DIB-R) were used as the diagnostic instruments for BPD.Results: Recovered patients had a 48% lower prevalence of smoking than non -recovered patients at 6-year follow-up (a significant difference; P=.01). Also, the rate of decline in smoking for the recovered group was 68% and was significantly faster (P= .008) than for the non-recovered group over the subsequent 18 years. Alcohol abuse or dependence (relative risk [RR]=1.22; 95% CI,1.06-1.40; P=.005), lower levels of education (RR=1.28; 95% CI,1.15-1.42; P<.001), and higher levels of the defense mechanism of denial (RR=1.08; 95% CI,1.03-1.13; P=.002) were significant predictors of smoking in borderline patients in multivariate analyses.Conclusions: Taken together, the results of this study suggest that recovery status was an important element in the prevalence of smoking among borderline patients over time. They also suggest that smoking was predicted by 3 factors: prior psychopathology, demographics, and psychological maturity.
bookPart Transtornos de personalidade(2021) TAVARES, Hermano; TORRES, Renata Ferraz; BRAñAS, Marcelo José Abduch Adas; CROCI, Marcos Signoretti; MARTINHO JR., EduardobookPart Entrevista nos transtornos de personalidade(2023) CHO, Aline Jimi Myung; BRAñAS, Marcelo José Abduch Adas; CROCI, Marcos SignorettibookPart Inteligência(2021) CROCI, Marcos Signoretti; BRANãS, Marcelo José Abduch Adas; JúNIOR, Eduardo Martinho