ANA LUCIA MARTINS ARRUDA
Índice h a partir de 2011
3
Projetos de Pesquisa
Unidades Organizacionais
7 resultados
Resultados de Busca
Agora exibindo 1 - 7 de 7
- Parâmetros Ecocardiográficos e Sobrevida na Cardiopatia Chagásica com Disfunção Sistólica Importante(2014) RASSI, Daniela do Carmo; VIEIRA, Marcelo Luiz Campos; ARRUDA, Ana Lúcia Martins; HOTTA, Viviane Tiemi; FURTADO, Rogério Gomes; RASSI, Danilo Teixeira; RASSI, SalvadorBackground: Echocardiography provides important information on the cardiac evaluation of patients with heart failure. The identification of echocardiographic parameters in severe Chagas heart disease would help implement treatment and assess prognosis. Objective: To correlate echocardiographic parameters with the endpoint cardiovascular mortality in patients with ejection fraction < 35%. Methods: Study with retrospective analysis of pre-specified echocardiographic parameters prospectively collected from 60 patients included in the Multicenter Randomized Trial of Cell Therapy in Patients with Heart Diseases (Estudo Multicêntrico Randomizado de Terapia Celular em Cardiopatias) - Chagas heart disease arm. The following parameters were collected: left ventricular systolic and diastolic diameters and volumes; ejection fraction; left atrial diameter; left atrial volume; indexed left atrial volume; systolic pulmonary artery pressure; integral of the aortic flow velocity; myocardial performance index; rate of increase of left ventricular pressure; isovolumic relaxation time; E, A, Em, Am and Sm wave velocities; E wave deceleration time; E/A and E/Em ratios; and mitral regurgitation. Results: In the mean 24.18-month follow-up, 27 patients died. The mean ejection fraction was 26.6 ± 5.34%. In the multivariate analysis, the parameters ejection fraction (HR = 1.114; p = 0.3704), indexed left atrial volume (HR = 1.033; p < 0.0001) and E/Em ratio (HR = 0.95; p = 0.1261) were excluded. The indexed left atrial volume was an independent predictor in relation to the endpoint, and values > 70.71 mL/m2 were associated with a significant increase in mortality (log rank p < 0.0001). Conclusion: The indexed left atrial volume was the only independent predictor of mortality in this population of Chagasic patients with severe systolic dysfunction.
- Cardiac obstruction secondary to metastatic invasion - A rare complication of Human Herpes Virus 8-positive plasmablastic lymphoma in acquired immunodeficiency syndrome(2012) PADUA, Daniele; RODRIGUES, Ana Clara; BARROS, Sergio; ARRUDA, Ana Lucia; CASTRO, Marianne; ANDRADE, Jose LazaroHuman herpes virus 8 (HHV8)-positive plasmablastic lymphoma (PBL) is a particularly rare and aggressive subtype of non-Hodgkin lymphoma, strongly associated with human immunodeficiency virus infection, with poor response to therapy and short survival. Characteristically, it shows proliferation of large plasmablastic cells with often eccentrically placed nuclei, with immunohistochemical assay positive for HHV8 latent nuclear antigen 1 and IgM. Primary mediastinal occurrence of a HHV8-positive PBL is rare and metastatic disease even more uncommon; tumor invasion to the heart leading to intracardiac obstruction with a rapidly fatal disease course has not been previously described.
conferenceObject SUBTLE IMPAIRMENT OF RIGHT VENTRICULAR FUNCTION IN SYSTEMIC SCLEROSIS WITH LUNG FIBROSIS DETECTED BY TISSUE DOPPLER(2014) SAMPAIO-BARROS, P.; RODRIGUES, A. C.; ROQUE, M.; ARRUDA, A. L.; BECKER, D.; BARROS, S.; KAY, F.; EMMERICH, T.; CERRI, G.conferenceObject Pulmonary Complications in Right Sided Endocarditis(2013) RODRIGUES, Ana Clara T.; KAY, Fernando U.; OGAWA, Andrea; NISHIYAMA, Katia; ARRUDA, Ana Lucia; LIRA FILHO, Edgar; KOWATSCH, Ingrid; FURTADO, Meive; CERRI, Glovanni G.; ANDRADE, Jose L.- Avaliação da Função Diastólica do Ventrículo Esquerdo com Ecocardiografia Associada a Doppler Tecidual na Esclerose Sistêmica(2017) ROQUE, Marina Carneiro de Freitas; SAMPAIO-BARROS, Percival D.; ARRUDA, Ana Lucia; BARROS-GOMES, Sergio; BECKER, Derly; ANDRADE, Jose Lazaro de; RODRIGUES, Ana Clara TudeBackground: Systemic sclerosis (SS) is a connective tissue abnormality characterized by fibrosis of the skin and internal organs. Cardiac involvement with consequent myocardial dysfunction in SS is associated with increased morbidity and mortality. Objective: To investigate the left ventricular (LV) diastolic function in patients with SS and preserved systolic function. Methods: Patients with SS were evaluated with two-dimensional echocardiography with tissue Doppler for analysis of chamber diameters, LV mass index (LVMI), indexed left atrial volume (iLAV), systolic function of both ventricles, and presence and degree of diastolic dysfunction (DD). Results: We evaluated 50 patients, divided according to the presence of DD into Group 1 (n = 25; normal diastolic function, E/A ratio >= 0.8, deceleration time [DT] > 150 ms and < 200 ms, and septal e' > 8 cm/s) and Group 2 (n = 25; with DD, subdivided into type I DD [E/A < 0.8, DT > 200 ms], type II [E/A = 0.8, septal e' < 8 cm/s, iLAV > 34 mL/m (2)], and type III [E/A > 2, DT < 150 ms, septal e' < 8 cm/s]). Type I DD was the most frequent (34%), followed by type II DD (16%). LVMI and iLAV were similar in both groups, but septal and lateral e' were reduced only in Group 2. In Group 2, we observed that patients with moderate DD had longer disease duration (p = 0.02). Conclusion: The prevalence of type I DD was elevated in SS and associated with aging. Disease duration emerged as an important factor in moderate DD.
- Importance of Adequately Performed Valsalva Maneuver to Detect Patent Foramen Ovale during Transesophageal Echocardiography(2013) RODRIGUES, Ana Clara; PICARD, Michael H.; CARBONE, Aime; ARRUDA, Ana Lucia; FLORES, Thais; KLOHN, Juliana; FURTADO, Meive; LIRA-FILHO, Edgar B.; CERRI, Giovanni G.; ANDRADE, Jose L.Background: Transesophageal echocardiography (TEE) plays an important role in evaluating cardioembolic sources of emboli. The identification of a patent foramen ovale (PFO) is reportedly improved with TEE compared with transthoracic echocardiography (TTE), but the Valsalva maneuver during TEE may be difficult or suboptimal. The aim of this study was to assess the efficacy of the Valsalva maneuver for PFO diagnosis using TEE compared with TTE by evaluating patients with ischemic stroke referred for echocardiography. Methods: Only patients able to perform the Valsalva maneuver during TTE were included; efficacy was defined by a 20 cm/sec decrease in transmitral E velocity. A PFO was judged present when microbubbles of agitated intravenous saline were seen in the left chambers within three cycles after right atrial opacification. Results: Of 108 patients (mean age, 55615 years; 61 men), 48 (44%) were judged to have PFOs by TEE and/or TTE. In 36 patients (33% of the total, 75% of those with PFOs), microbubbles were observed both by TEE and TTE, in seven patients only during TTE, and in five patients only during TEE. In patients able to satisfactorily perform the Valsalva maneuver during TEE, 22 PFOs were found, and two shunts (9%) were missed, whereas in patients unable to perform this maneuver, 26 PFOs were observed, with five shunts missed (19%) (P <.05). When a PFO was missed by TTE, either the echocardiographic window was suboptimal or the shunt was small. Conclusions: An adequate Valsalva maneuver is crucial for diagnosis of PFO; most patients with stroke may be screened using TTE with contrast and the Valsalva maneuver, with TEE indicated in case of suboptimal transthoracic images.
- Rupture of a giant aneurysm of the pulmonary artery caused by schistosomiasis(2012) PIVETA, Rafael B.; ARRUDA, Ana L.; RODRIGUES, Ana C.; PINHEIRO, Jairo A.; ANDRADE, Jose L.