FABRICIO LEITE DE CARVALHO

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LIM/55 - Laboratório de Urologia, Hospital das Clínicas, Faculdade de Medicina

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    IMPACT OF DETRUSOR SPHINCTER DYSSYNERGIA ON CLINICAL AND URODYNAMIC PARAMETERS OF PATIENTS WITH NEUROMYELITIS OPTICA
    (2012) CARVALHO, Fabricio; GOMES, Cristiano; PEREIRA, Samira; BESSA JR., Jose; CALLEGARO, Dagoberto; MARCHIORI, Paulo; BRUSCHINI, Homero; SROUGI, Miguel
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    ASSESSMENT OF THE MALE SEXUAL QUOTIENT SCALE RELIABILITY TO EVALUATE SEXUAL FUNCTION OF MEN WITH SPINAL CORD INJURY
    (2015) MIRANDA, Eduardo; GOMES, Cristiano; BESSA JUNIOR, Jose de; CASTRO FILHO, Jose de; BELLUCCI, Carlos; BATTISTELLA, Linamara; BARROS FILHO, Tarcisio; CARVALHO, Fabricio; ABDO, Carmita; BRUSCHINI, Homero; NAHAS, William; SROUGI, Miguel
  • article 18 Citação(ões) na Scopus
    Voiding Dysfunction in Patients With Neuromyelitis Optica Spectrum Disorders
    (2016) CARVALHO, Fabricio Leite de; GOMES, Cristiano Mendes; APOSTOLOS-PEREIRA, Samira L.; BESSA JR., Jose; PINHEIRO, Marcello; MARCHIORI, Paulo E.; BRUSCHINI, Homero; SROUGI, Miguel; CALLEGARO, Dagoberto
    Aims: We assessed the lower urinary tract symptoms (LUTS) and urodynamic findings in patients with neuromyelitis optica spectrum disorders (NMO-SD), a recently defined neurological disease. Methods: We prospectively evaluated seven men and 23 women (mean age 41.1 +/- 13.5 years) with an established diagnosis of NMO-SD who were invited to participate irrespective of the presence of LUTS. Neurological evaluation was assessed with the Expanded Disability Status Scale (EDSS) and LUTS were evaluated with the Overactive Bladder questionnaire (OAB-V8) and the International Prostate Symptom Score (I-PSS). All patients underwent videourodynamics, transabdominal urinary tract sonography, urine culture, and serum creatinine levels. Results: The mean time of disease duration was 33.8 +/- 30.8 months. Neurological evaluation showed a mean EDSS score of 5.3 +/- 1.8. The most frequent videourodynamic findings were detrusor-sphincter dyssynergia (DSD) and detrusor overactivity (DO) in 11 (36.6%) patients, DSD without DO in seven (23.3%) and DO without DSD in six (20.0%) patients. Voiding dysfunction assessed by I-PSS and OAB-V8 increased with the degree of neurological impairment (P = 0.018; r = 0.42 and P = 0.006; r = 0.48 respectively). Patients with DSD had higher I-PSS (18.5 +/- 11.4 vs 7.0 +/- 9.2; P = 0.029) and OAB-V8 scores (22.8 +/- 15.8vs 9.1 +/- 7.8; P = 0.008), and worse neurological impairment (mean EDSS 5.9 +/- 1.8 vs 4.5 +/- 1.5; P = 0.027). Conclusions: Most patients with NMO-SD have LUTS and voiding dysfunction, with DSD and DO as the main urodynamic findings. The severity of the neurological disease is a predictive factor for the occurrence of voiding dysfunction and detrusor-sphincter dyssynergia. (C) 2014 Wiley Periodicals, Inc.
  • article 16 Citação(ões) na Scopus
    Evaluation of Sexual Dysfunction in Men With Spinal Cord Injury Using the Male Sexual Quotient
    (2016) MIRANDA, Eduardo P.; GOMES, Cristiano Mendes; BESSA JR., Jose de; ABDO, Carmita Helena Najjar; BELLUCCI, Carlos Henrique Suzuki; CASTRO FILHO, Jose Everton de; CARVALHO, Fabricio Leite de; SOUZA, Daniel Rubio de; BATTISTELLA, Linamara Rizzo; SCAZUFCA, Marcia; BRUSCHINI, Homero; BARROS FILHO, Tarcisio; SROUGI, Miguel.
    Objective: To assess different aspects of sexual function in men with spinal cord injury (SCI) using the Male Sexual Quotient (MSQ), a newly developed tool to assess sexual function and satisfaction. Design: Cross-sectional study. Setting: Tertiary rehabilitation center. Participants: Patients (N=295) older than 18 years (mean age +/- SD, 40.7 +/- 14.5y) with SCI for more than 1 year (median time since SCI, 3.6y; range, 1.6-7.0y) were assessed from February to August 2012. Patients completed the MSQ questionnaire and the Sexual Health Inventory for Men (SHIM). Interventions: Not applicable. Main Outcome Measures: Performance in various domains of sexual function was evaluated using the MSQ and SHIM questionnaires. Results: Erectile function, ejaculation, and orgasm were the most severely affected domains. The median MSQ score was 40 (range, 8-66), and the median SHIM score was 5 (range, 0-16). The diagnostic properties of the 2 instruments were similar in the discrimination of sexually active subjects. The area under the receiver operating characteristic curve was .950 (95% confidence interval [CI], .923.979) for the MSQ and .942 (95% CI, .915.968) for the SHIM. There was a strong correlation between the 2 instruments (r=.826; 95% CI, .802.878). Conclusions: Different domains of sexual function are severely impaired in men with SCI, although their sexual interest remains high. The MSQ and SHIM scores strongly correlate, but the MSQ provides a more comprehensive assessment of sexual dysfunction in male patients with SCI. (C) 2016 by the American Congress of Rehabilitation Medicine