LEANDRO TAVARES LUCATO
Projetos de Pesquisa
Unidades Organizacionais
Instituto de Radiologia, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/44 - Laboratório de Ressonância Magnética em Neurorradiologia, Hospital das Clínicas, Faculdade de Medicina
LIM/44 - Laboratório de Ressonância Magnética em Neurorradiologia, Hospital das Clínicas, Faculdade de Medicina
13 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 13
- Teaching NeuroImages: Lacunar stroke and polyarteritis nodosa Consider ADA2 deficiency (DADA2)(2019) GONCALVES, Tayrine da Silva; ALVES, Cesar Augusto Pinheiro Ferreira; PAZ, Jose Albino da; LUCATO, Leandro Tavares
conferenceObject Clinical Course of LETM Associated with Neuroschistosomiasis(2013) APOSTOLOS-PEREIRA, Samira; MARCHIORI, Paulo; MACHADO, Luis; LIVRAMENTO, Jose; GOMES, Helio; LUCATO, Leandro; CALLEGARO, Dagoberto- Insular and anterior cingulate cortex deep stimulation for central neuropathic pain Disassembling the percept of pain(2019) GALHARDONI, Ricardo Geront; SILVA, Valquiria Aparecida da; GARCIA-LARREA, Luis; DALE, Camila; BAPTISTA, Abrahao F.; BARBOSA, Luciana Mendonca; MENEZES, Luciana Mendes Bahia; SIQUEIRA, Silvia R. D. T. de; VALERIO, Fernanda; ROSI JR., Jefferson; RODRIGUES, Antonia Lilian de Lima; FERNANDES, Diego Toledo Reis Mendes; SELINGARDI, Priscila Mara Lorencini; MARCOLIN, Marco Antonio; DURAN, Fabio Luis de Souza; ONO, Carla Rachel; LUCATO, Leandro Tavares; FERNANDES, Ana Mercia B. L.; SILVA, Fabio E. F. da; YENG, Lin T.; BRUNONI, Andre R.; BUCHPIGUEL, Carlos A.; TEIXEIRA, Manoel J.; ANDRADE, Daniel Ciampi deObjective To compare the analgesic effects of stimulation of the anterior cingulate cortex (ACC) or the posterior superior insula (PSI) against sham deep (d) repetitive (r) transcranial magnetic stimulation (TMS) in patients with central neuropathic pain (CNP) after stroke or spinal cord injury in a randomized, double-blinded, sham-controlled, 3-arm parallel study. Methods Participants were randomly allocated into the active PSI-rTMS, ACC-rTMS, sham-PSI-rTMS, or sham-ACC-rTMS arms. Stimulations were performed for 12 weeks, and a comprehensive clinical and pain assessment, psychophysics, and cortical excitability measurements were performed at baseline and during treatment. The main outcome of the study was pain intensity (numeric rating scale [NRS]) after the last stimulation session. Results Ninety-eight patients (age 55.02 +/- 12.13 years) completed the study. NRS score was not significantly different between groups at the end of the study. Active rTMS treatments had no significant effects on pain interference with daily activities, pain dimensions, neuropathic pain symptoms, mood, medication use, cortical excitability measurements, or quality of life. Heat pain threshold was significantly increased after treatment in the PSI-dTMS group from baseline (1.58, 95% confidence interval [CI] 0.09-3.06]) compared to sham-dTMS (-1.02, 95% CI -2.10 to 0.04, p = 0.014), and ACC-dTMS caused a significant decrease in anxiety scores (-2.96, 95% CI -4.1 to -1.7]) compared to sham-dTMS (-0.78, 95% CI -1.9 to 0.3; p = 0.018). Conclusions ACC- and PSI-dTMS were not different from sham-dTMS for pain relief in CNP despite a significant antinociceptive effect after insular stimulation and anxiolytic effects of ACC-dTMS. These results showed that the different dimensions of pain can be modulated in humans noninvasively by directly stimulating deeper SNC cortical structures without necessarily affecting clinical pain per se.
- Teaching NeuroImages: Limbic encephalitis associated with relapsing polychondritis(2016) SIMABUKURO, Mateus Mistieri; LUCATO, Leandro Tavares; SHINJO, Samuel Katsuyuki; FLORES, Wellington Lima; CASTRO, Luiz Henrique MartinsA 43-year-old man presented with subacute fever, costochondritis, headache, seizures, and amnesia. Brain MRI (figure) showed bilateral temporal lobe hyperintensities. CSF revealed 105 white cells/mm(3) (77% lympho-monocytes), elevated protein, and normal glucose. Infection and paraneoplastic/autoimmune workup was negative. He improved after corticosteroid treatment.
- Author response: Insular and anterior cingulate cortex deep stimulation for central neuropathic pain: Disassembling the percept of pain(2020) ANDRADE, Daniel Ciampi de; GALHARDONI, Ricardo; SILVA, Valquiria Aparecida da; GARCIA-LARREA, Luis; DALE, Camila; BAPTISTA, Abrahao F.; BARBOSA, Luciana Mendonca; MENEZES, Luciana Mendes Bahia; SIQUEIRA, Silvia R. D. T. de; VALERIO, Fernanda; ROSI, Jefferson; RODRIGUES, Antonia Lilian de Lima; FERNANDES, Diego Toledo Reis Mendes; SELINGARDI, Priscila Mara Lorencini; MARCOLIN, Marco Antonio; DURAN, Fabio Luis de Souza; ONO, Carla Rachel; LUCATO, Leandro Tavares; FERNANDES, Ana Mercia B. L.; SILVA, Fabio E. F. da; YENG, Lin T.; BRUNONI, Andre R.; BUCHPIGUEL, Carlos A.; TEIXEIRA, Manoel J.
- Teaching NeuroImages: Bilateral intracerebral hemorrhage in expanded dengue syndrome(2017) CAVALCANTE, Wagner Cid Palmeira; SOARES NETO, Herval Ribeiro; GRATIVVOL, Ronnyson Susano; SPERA, Raphael Ribeiro; FRASSETTO, Fernando Pereira; LUCATO, Leandro Tavares; NITRINI, Ricardo
article 25 Citação(ões) na Scopus COPPER DEFICIENCY MYELONEUROPATHY IN A PATIENT WITH WILSON DISEASE(2011) SILVA-JUNIOR, F. P. da; MACHADO, A. A. C.; LUCATO, L. T.; CANCADO, E. L. R.; BARBOSA, E. R.conferenceObject Differential Diagnosis of Longitudinally Extensive Transverse Myelitis(2013) APOSTOLOS-PEREIRA, Samira; MARCHIORI, Paulo; DELLAVANCE, Alessandra; LUCATO, Leandro; JORGE, Frederico; SIMM, Renata; SATO, Douglas; CALLEGARO, DagobertoconferenceObject AMPA Receptor Antibody Encephalitis in a Young Man Associated with Atypical Findings. Case report(2016) PINTO, Lecio; SIMABUKURO, Mateus; SPERA, Raphael; PARK, Marcelo; PAQUISI, Arlindo; PEDRUCI, Lucas; KUKITA, Camila; LUCATO, Leandro; CASTRO, Luiz; NITRINI, Ricardo- Spectrum of cognitive impairment in neurocysticercosis Differences according to disease phase(2012) RODRIGUES, C. L.; ANDRADE, D. C. de; LIVRAMENTO, J. A.; MACHADO, L. R.; ABRAHAM, R.; MASSAROPPE, L.; LUCATO, L. T.; CARAMELLI, P.Objectives: Cognitive decline related to neurocysticercosis (NC) remains poorly characterized and underdiagnosed. In a cross-sectional study with a prospective phase, we evaluated cognitive decline in patients with strictly calcified form (C-NC), the epidemiologically largest subgroup of NC, and investigated whether there is a spectrum of cognitive abnormalities in the disease. Methods: Forty treatment-naive patients with C-NC aged 37.6 +/- 11.3 years and fulfilling criteria for definitive C-NC were submitted to a comprehensive cognitive and functional evaluation and were compared with 40 patients with active NC (A-NC) and 40 healthy controls (HC) matched for age and education. Patients with dementia were reassessed after 24 months. Results: Patients with C-NC presented 9.4 +/- 3.1 altered test scores out of the 30 from the cognitive battery when compared to HC. No patient with C-NC had dementia and 10 patients (25%) presented cognitive impairment-no dementia (CIND). The A-NC group had 5 patients (12.5%) with dementia and 11 patients (27.5%) with CIND. On follow-up, 3 out of 5 patients with A-NC with dementia previously still presented cystic lesions with scolex on MRI and still had dementia. One patient died and the remaining patient no longer fulfilled criteria for either dementia or CIND, presenting exclusively calcified lesions on neuroimaging. Conclusions: Independently of its phase, NC leads to a spectrum of cognitive abnormalities, ranging from impairment in a single domain, to CIND and, occasionally, to dementia. These findings are more conspicuous during active vesicular phase and less prominent in calcified stages.