BRUNO PINATTI FERREIRA DE SOUZA
Índice h a partir de 2011
2
Projetos de Pesquisa
Unidades Organizacionais
Instituto de Psiquiatria, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/21 - Laboratório de Neuroimagem em Psiquiatria, Hospital das Clínicas, Faculdade de Medicina
LIM/21 - Laboratório de Neuroimagem em Psiquiatria, Hospital das Clínicas, Faculdade de Medicina
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bookPart Interconsulta em cardiologia(2021) JúNIOR, Renério Fráguas; SOUZA, Bruno Pinatti Ferreira; ANDREI, Anna Maria; ANDRADE, Milena Gross de; SERRANO JR., Carlos Vicente; WAJNGARTEN, MauriciobookPart Interconsulta em doenças reumatológicas e musculoesqueléticas(2021) JúNIOR, Renério Fráguas; SOUZA, Bruno Pinatti Ferreira de; RODRIGUES, Carlos Ewerton Maia; CARVALHO, Josélio Freire de- Loss of interest, depressed mood and impact on the quality of life: Cross-sectional survey(2011) GUAJARDO, Valeri D.; SOUZA, Bruno P. F.; HENRIQUES, Sergio G.; LUCIA, Mara C. S.; MENEZES, Paulo R.; MARTINS, Milton A.; TARDIVO, Leila S. L. P. C.; GATTAZ, Wagner F.; FRAGUAS, RenerioBackground: Depressive symptoms and chronic disease have adverse effects on patients' health-related quality of life (H-RQOL). However, little is known about this effect on H-RQOL when only the two core depressive symptoms - loss of interest and depressed mood - are considered. The objective of this study is to investigate H-RQOL in the presence of loss of interest and depressed mood at a general medical outpatient unit. Methods: We evaluated 553 patients at their first attendance at a general medical outpatient unit of a teaching hospital. H-RQOL was assessed with the Medical Outcomes Study 36-item Short-Form Health Survey (SF-36). Depressed mood and loss of interest were assessed by the Primary Care Evaluation of Mental Disorders (PRIME-MD)Patient Questionnaire. A physician performed the diagnosis of chronic diseases by clinical judgment and classified them in 13 possible pre-defined categories. We used multiple linear regression to investigate associations between each domain of H-RQOL and our two core depression symptoms. The presence of chronic diseases and demographic variables were included in the models as covariates. Results: Among the 553 patients, 70.5% were women with a mean age of 41.0 years (range 18-85, SD +/- 15.4). Loss of interest was reported by 54.6%, and depressed mood by 59.7% of the patients. At least one chronic disease was diagnosed in 59.5% of patients; cardiovascular disease was the most prevalent, affecting 20.6% of our patients. Loss of interest and depressed mood was significantly associated with decreased scores in all domains of H-RQOL after adjustment for possible confounders. The presence of any chronic disease was associated with a decrease in the domain of vitality. The analysis of each individual chronic disease category revealed that no category was associated with a decrease in more than one domain of H-RQOL. Conclusion: Loss of interest and depressed mood were associated with significant decreases in H-RQOL. We recommend these simple tests for screening in general practice.
- Heart rate variability and depression(2021) FRAGUAS, R.; SOUZA, B. P. F. deHeart rate variability (HRV) is defined as the changes in the time intervals between consecutive heartbeats. These changes are expected to occur and reflect the autonomic nervous system (ANS) activity. Depression has been associated with reduced HRV particularly with high-frequency power HRV (HF-HRV), standard deviation of NN intervals (SDNN), and root mean square of successive NN interval differences (RMSSD) indices. The concept that low-frequency power HRV (LF-HRV) is an index of sympathetic tonus has been questioned and whether it is reduced or increased in depressed subjects is still controversial. The LF/HF ratio was found to be increased in two meta-analyses, however, its role as an index of sympathetic/parasympathetic imbalance has been questioned. Treatment of depression may be followed by amelioration of some HRV parameters, but most antidepressants decrease HRV. The reduction of HRV is traditionally considered as one of the mechanisms in the association of depression and cardiovascular disease (CVD). However, data support that HRV changes may precede depression, being a mark of decreased parasympathetic tonus, which would represent a vulnerability do depression. © 2021 Elsevier Inc. All rights reserved.
bookPart Interconsulta Psiquiátrica no Hospital Geral(2016) TERRONI, Luisa de Marillac Niro; SOUZA, Bruno Pinatti Ferreira de; HUMES, Eduardo de Castro; FRAGUAS, ReneriobookPart Interconsulta psiquiátrica: conceitos(2021) JúNIOR, Renério Fráguas; SOUZA, Bruno Pinatti FerreirabookPart Princípios da abordagem terapêutica em interconsulta(2021) FRáGUAS JUNIOR, Renério; SOUZA, Bruno Pinatti Ferreira debookPart Pneumologia e tisiologia(2016) TORQUATO JUNIOR, Marco Antônio Abud; SOUZA, Bruno Pinatti Ferreira debookPart Cardiologia(2016) JúNIOR, Renério Fráguas; SOUZA, Bruno Pinatti Ferreira de