RENATA CARVALHO DE MIRANDA CHAVES

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  • article 0 Citação(ões) na Scopus
  • bookPart 0 Citação(ões) na Scopus
    Acid indigestion: Causes, symptoms and treatment options
    (2014) CHAVES, R. C. M.; NAVARRO-RODRIGUEZ, T.
    Acid indigestion is a term commonly used by patients and physicians to indicate some form of gastrointestinal tract upset [1]. It includes a wide variety of symptoms, such as early satiety, nausea, bloating and abdominal discomfort. These vague upper gastrointestinal symptoms have been termed dyspepsia [2]. Functional dyspepsia, which is characterized by persistent or recurrent pain or discomfort centered in the upper abdomen based on Rome criteria, is accounted to be approximately 20% in the general population [3]. Occasionally, patients use the term indigestion to describe heartburn. However, it is defined more specifically as a burning sensation in the retroesternal area of variable intensity [4]. Likewise, this retroesternal burning, is the mainly symptom associated with gastroesophageal reflux disease (GERD) [5]. The epidemiological aspects of heartburn and GERD have been object of growing interest in the last decade because its increasing prevalence and the complications of the disease [6]. Population-based studies suggest that GERD is a common condition with a prevalence ranging between 10-20% in North America [4]. The impact of GERD extends beyond its economic burden, as it significantly impaired health-related quality of life [5]. Both dyspepsia and GERD are frequent chronic, often need long term treatment. Moreover, several studies have reported a higher prevalence of dyspeptic symptoms in patients with GERD [3]. In this chapter, we will review the cause, identify the symptoms and discuss treatment of patients with heartburn and acid indigestion. © 2014 by Nova Science Publishers, Inc. All rights reserved.
  • bookPart
    Doença do refluxo gastresofágico
    (2013) MORAES-FILHO, Joaquim Prado Pinto de; CHAVES, Renata Carvalho de Miranda; DIB, Ricardo Anuar; NAVARRO-RODRIGUEZ, Tomás
  • bookPart
    Constipação intestinal funcional
    (2013) NAVARRO-RODRIGUEZ, Tomás; DIB, Ricardo Anuar; CHAVES, Renata Carvalho de Miranda; MORAES-FILHO, Joaquim Prado Pinto de
  • article 27 Citação(ões) na Scopus
    Respiratory physiotherapy can increase lower esophageal sphincter pressure in GERD patients
    (2012) CHAVES, Renata Carvalho de Miranda; SUESADA, Milena; POLISEL, Fabiane; SA, Claudia Cristina de; NAVARRO-RODRIGUEZ, Tomas
    Background: Inspiratory muscle training (IMT) has been shown to increase diaphragm thickness. We evaluated the effect of IMT on mid-respiratory pressure (MRP) in patients with gastroesophageal reflux disease (GERD) and hypotensive lower esophageal sphincter (LES), and compared the results with a sham group. Methods: Twenty consecutive patients (progressive loading group) and 9 controls (sham group) were included. All patients had end expiratory pressure (EEP) between 5 and 10 mmHg, underwent esophageal manometry and pulmonary function tests before and after 8 weeks of training, and used a threshold IMT twice daily. The threshold IMT was set at 30% of the maximal inspiratory pressure for the progressive loading group; while, the threshold for sham-treated patients was set at 7 cmH(2)O for the whole period. Results: There was an increase in MRP in 15 (75%) patients in the progressive loading group, with an average gain of 46.6% (p<0.01), and in six (66%) patients in the sham group with a mean increase of 26.2% (p<0.01). However, there was no significant difference between the groups (p = 0.507). The EEP also increased compared with measurements before training (p<0.01), but it did not differ between groups (p = 0.727). Conclusion: IMT increased LES pressure in patients with GERD, in both the treatment and sham groups, after an eight-week program. Although there was no statistically significant difference between groups, suggesting the pressure increase in LES occurs regardless of the resistance load of the threshold IMT. These findings need to be confirmed in further studies with a larger sample. Registration number: 0922/09.