FILUMENA MARIA DA SILVA GOMES
Projetos de Pesquisa
Unidades Organizacionais
Departamento de Pediatria, Faculdade de Medicina
46 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 46
bookPart Triagem das principais deficiências de micronutrientes na infância(2013) VALENTE, Maria Helena; GOMES, Filumena Maria da Silva; BRENTANI, AlexandrabookPart Resfriado comum e influenza(2022) GOMES, Filumena Maria da Silva; VALENTE, Maria Helena; NOVO, Ana Carolina de Albuquerque Cavalcanti Ferreira- No Association between Low Birth Weight and Cardiovascular Risk Factors in Early Adulthood: Evidence from Sao Paulo, Brazil(2013) GOMES, Filumena Maria; SUBRAMANIAN, S. V.; ESCOBAR, Ana Maria de Ulhoa; VALENTE, Maria Helena; GRISI, Sandra Josefina Ferraz Ellero; BRENTANI, Alexandra; FINK, GuentherBackground: A growing literature suggests that low birth weight increases the risk of poor health outcomes in adulthood. We tested this hypothesis among young adults living in Sao Paulo State, Brazil. Methods and Findings: To identify the effects of low birth weight on young adulthood outcomes, a medical assessment of 297 individuals born between 1977 and 1989 was conducted at a primary care unit in Sao Paulo State, Brazil. We analyzed body mass index (BMI), waist-hip ratio, blood pressure, fasting glucose and total cholesterol levels using linear and logistic regressions. Low birth was negatively associated with BMI (beta = 22.0, 95% CI: 23.69, 20.27, p = 0.02), fasting glucose levels (beta = 21.9, 95% CI: 23.9, 20.07, p = 0.05), waist-hip ratio (beta = 20.03, 95% CI: 20.07, 20.01, p = 0.10), systolic blood pressure (beta = 23.32, 95% CI: 27.60, 0.96, p = 0.12), and total cholesterol levels (beta = 23.19, 95% CI: 216.43, 10.05, p = 0.636). Low birth weight was also associated with lower odds of young adults being overweight and obese, but neither association was statistically significant. Weight gain in the first 12 months of life was associated with higher adult BMI (beta = 0.79, 95% CI: 20.0455, 1.623, p = 0.064) and blood pressure (beta = 2.79, 95% CI: 0.22, 5.35, p = 0.034). No associations were found between low birth weight and early life (catch-up) growth. Conclusions: Low birth weight was not associated with poor health outcomes among young adults in Brazil. These results appear inconsistent with the original Barker hypothesis, but will need to be corroborated in larger samples with longer follow-ups to allow a more general evaluation of the validity of the hypothesis in low and middle income countries.
bookPart Desenvolvimento cognitivo adaptativo(2018) GOMES, Filumena Maria da Silva; VALENTE, Maria Helena; NOVO, Ana Carolina de A. C. FerreirabookPart Crescimento: influências fetais, a importância do catch-up do crescimento e a prevenção da obesidade(2013) GOMES, Filumena Maria da Silva; VALENTE, Maria Helena; ESCOBAR, Ana Maria de Ulhôa; BRENTANI, Alexandra; GRISI, Sandra Josefina Ferraz EllerobookPart Cetoacidose diabética em crianças e adolescentes: diagnóstico e tratamento(2022) VALENTE, Maria Helena; GOMES, Filumena Maria da Silva- Relation between Birth Weight, Growth, and Subclinical Atherosclerosis in Adulthood(2015) VALENTE, Maria Helena; GOMES, Filumena Maria da Silva; BENSENOR, Isabela Judith Martins; BRENTANI, Alexandra Valeria Maria; ESCOBAR, Ana Maria de Ulhoa; GRISI, Sandra J. F. E.Background and Objectives. Adverse conditions in the prenatal environment and in the first years of life are independently associated with increased risk for cardiovascular disease. This paper aims to study the relation between birthweight, growth in the first year of life, and subclinical atherosclerosis in adults. Methods. 88 adults aged between 20 and 31 were submitted to sociodemographic qualities, anthropometric data, blood pressure measurements, metabolic profile, and evaluation of subclinical atherosclerosis. Results. Birthweight <2,500 grams (g) was negatively correlated with (a) increased waist-to-hip ratio (WHR), according to regression coefficient (RC) equal to -0.323, 95% CI [-0.571, -0.075] P < 0.05; (b) diastolic blood pressure (RC = -4.744, 95% CI [-9.017, -0.470] P < 0.05); (c) low HDL-cholesterol (RC = -0.272, 95% CI [-0.516, -0.029] P < 0.05); (d) frequency of intima-media thickness (IMT) of left carotid >75th percentile (RC = -0.242, 95% CI [-0.476, -0.008] P < 0.05). Birthweight >3,500 g was associated with (a) BMI >25.0 kg/m(2), (RC = 0.317, 95% CI [0.782, 0.557] P < 0.05); (b) increased waist circumference (RC = 0.284, 95% CI [0.054, 0.513] P < 0.05); (c) elevated WHR (RC = 0.280, 95% CI [0.054, 0.505] P < 0.05); (d) minimum subcutaneous adipose tissue (SAT) (RC = 4.354, 95% CI [0.821, 7.888] P < 0.05); (e) maximum SAT (RC = 7.095, 95% CI [0.608, 13.583] P < 0.05); (f) right lobe of the liver side (RC = 6.896, 95% CI [1.946, 11.847] P < 0.001); (g) frequency's right lobe of the liver >75th percentile (RC = 0.361, 95% CI [0.169, 0.552] P < 0.001). Weight gain in the first year of life was inversely correlated with (a) mean IMT of left carotid (RC = -0.046, 95% CI [-0.086, -0.006] P < 0.05; (b) frequency IMT of left carotid > 75th percentile (RC = -0.253, 95% CI [-0.487, -0.018] P < 0.05); (c) mean IMT (RC = -0.038, 95% CI [0.073, -0.002] P < 0.05); (d) the frequency of the mean IMT > 75th percentile (RC = -0.241, 95% CI [-0.442, -0.041] P < 0.05). Conclusions. Adults birthweight <2,500 g and >3,500 g and with insufficient weight gain in the first year of life have showed different metabolic phenotypes, but all of them were related to subclinical atherosclerosis.
bookPart Triagem do comportamento seguro(2013) GOMES, Filumena Maria da Silva; ESCOBAR, Ana Maria de Ulhôa; WAKSMAN, Renata Dejtiar; BRENTANI, Alexandra; SILVA, Alexandre Funcia de AzeredobookPart Covid-19 em crianças e adolescentes: diagnóstico e tratamento(2022) VALENTE, Maria Helena; GOMES, Filumena Maria da SilvabookPart Pneumonias bacterianas comunitárias em pediatria: diagnóstico e tratamento(2022) VALENTE, Maria Helena; GOMES, Filumena Maria da Silva