TALITA ZERBINI
Projetos de Pesquisa
Unidades Organizacionais
LIM/40 - Laboratório de Imunohematologia e Hematologia Forense, Hospital das Clínicas, Faculdade de Medicina
9 resultados
Resultados de Busca
Agora exibindo 1 - 9 de 9
- Fitting mixed models to messy longitudinal data: A case study involving estimation of post mortem intervals(2019) SINGER, Julio M.; ROCHA, Francisco M. M.; ANDRE, Carmen D. S.; ZERBINI, TalitaNon-linear mixed models are useful in many practical longitudinal data problems, especially when they are derived as solutions to differential equations generated by subject matter theoretical considerations. When this underlying rationale is not available, practitioners are faced with the dilemma of choosing a model from the numerous ones available in the literature. The situation is even worse for messy data where interpretation and computational problems are frequent. This is the case with a pilot observational study conducted at the School of Medicine of the University of Sao Paulo in which a new method to estimate the time since death (post-mortem interval-PMI) is proposed. In particular, the attenuation of the density of intra-cardiac hypostasis (concentration of red cells in the vascular system by gravity) obtained from a series of tomographic images was observed in the thoraces of 21 bodies of hospitalized patients with known time of death. The images were obtained at different instants and not always at the same conditions for each body, generating a set of messy data. In this context, we consider three ad hoc models to analyse the data, commenting on the advantages and caveats of each approach.
- Differences between postmortem computed tomography and conventional autopsy in a stabbing murder case(2014) ZERBINI, Talita; SILVA, Luiz Fernando Ferraz da; FERRO, Antonio Carlos Goncalves; KAY, Fernando Uliana; AMARO JUNIOR, Edson; PASQUALUCCI, Carlos Augusto Goncalves; SALDIVA, Paulo Hilario do NascimentoOBJECTIVE: The aim of the present work is to analyze the differences and similarities between the elements of a conventional autopsy and images obtained from postmortem computed tomography in a case of a homicide stab wound. METHOD: Comparison between the findings of different methods: autopsy and postmortem computed tomography. RESULTS: In some aspects, autopsy is still superior to imaging, especially in relation to external examination and the description of lesion vitality. However, the findings of gas embolism, pneumothorax and pulmonary emphysema and the relationship between the internal path of the instrument of aggression and the entry wound are better demonstrated by postmortem computed tomography. CONCLUSIONS: Although multislice computed tomography has greater accuracy than autopsy, we believe that the conventional autopsy method is fundamental for providing evidence in criminal investigations.
- Evaluation of the discrepancy between clinical diagnostic hypotheses and anatomopathological diagnoses resulting from autopsies(2019) ZERBINI, Talita; SINGER, Julio M.; LEYTON, VilmaOBJECTIVES: An objective of clinical autopsies is to determine the final cause of death and the pathological changes that may have triggered it. Despite advances in Medicine, the level of discrepancy between clinical and autopsy diagnoses remains significant. The aim of this study was to compare the data obtained from autopsies carried out at the Sao Bernardo do Campo/SP Death Verification Section with clinical diagnostic hypotheses proposed during medical care. METHOD: This was a retrospective study involving the comparison of necroscopic reports issued by the Sao Bernardo do Campo/Sao Paulo Death Verification Section in 2014 and 2015 and the Cadaver Referral Guides completed by attending physicians prior to the necroscopic examination. RESULTS: A total of 465 cases were analyzed. In general, discrepancies between the clinical diagnostic hypothesis and the autopsy diagnosis occurred in 28% of the cases. A logistic regression model, with diagnostic discrepancy as a response variable and sex, age, duration of care, type of institution providing medical care and organ system as explanatory variables, was fit to the data; the results indicated that all explanatory variables with the exception of organ system are not significant (p>0.132). CONCLUSIONS: Discrepancies between clinical diagnostic hypotheses and autopsy diagnoses continue to occur, despite new developments in complementary examinations and therapies. The odds of a discrepancy when patients present with diseases of the cardiac system are greater than those when there are problems in the vascular, endocrine and neurological systems.
bookPart Aspectos éticos e jurídicos da perícia médico-legal em Sexologia Forense(2020) FERREIRA, Mariana da Silva; ZERBINI, Talita; CINTRA, Raquel BarbosabookPart O uso de exames de imagem na realização da autópsia(2020) ZERBINI, Talita- Scanning electron microscopy as an auxiliary method in the study of exhumed bones(2011) MELKI, Joao A. D.; MARTIN, Carmen C. S.; ZERBINI, TalitaScanning electronmicroscopy (SEM) has been used in forensic science in many ways. The reports of cases in which SEM has been used as an auxiliary method in the investigation of exhumed bones are rare. In this article, we report an exhumation that was made to determine if a seized weapon could have been used in a homicide. We used SEM to analyze a fracture in the interior of the skull of the victim. The findings described in this article showed us that it is possible to develop new researches in this field.
- Blood alcohol levels in suicide by hanging cases in the state of Sao Paulo, Brazil(2012) ZERBINI, Talita; PONCE, Julio de Carvalho; SINAGAWA, Daniele Mayumi; CINTRA, Raquel Barbosa; MUNOZ, Daniel Romero; LEYTON, VilmaSuicide is one of the main causes of violent death worldwide, and has become a public health issue. Since alcohol consumption is associated with the increase in the number of suicides and hanging is one of the main methods used worldwide, the present study consists of an epidemiological analysis of BACs in victims of suicide by hanging autopsied in the State of Sao Paulo, Brazil. The objective of the present work was to establish an epidemiological profile and evaluate blood alcohol concentrations in victims of suicide by hanging in the State of Sao Paulo, Brazil, in the year of 2007. A cross-sectional retrospective study was conducted by collection of secondary data from autopsy reports of victims of hanging. According to the present study, positive results for alcohol were higher in male victims, but the mean BAC was higher in women.
- Suicides by hanging and its association with meteorological conditions in Sao Paulo(2018) ZERBINI, Talita; GIANVECCHIO, Victor Alexandre Percinio; REGINA, Damaris; TSUJIMOTO, Tamy; RITTER, Victor; SINGER, Julio M.The main goal of this study was to evaluate the association between daily cases of hanging suicides and meteorological conditions in Sao Paulo, Brazil. We considered a retrospective observational study based on the analysis of all necroscopic medical-expert reports available in digital form from the central unit of the Instituto Medico Legal (Medical Legal Institute) of Sao Paulo between July 1, 2006 and June 31, 2007. The meteorological variables were combined via Principal Components Analysis. In order to explain their association with the frequency of suicides, Poisson regression models were employed. The analysis suggests that hotter and brighter days are associated with higher incidence of hanging suicides.
bookPart Doação voluntária de corpos para ensino e pesquisa(2020) ZERBINI, Talita; OLIVEIRA, Reinaldo Ayer de; MARTIN, Carmen Cinira Santos