CARLOS ALBERTO RUIZ

Índice h a partir de 2011
2
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina
LIM/58 - Laboratório de Ginecologia Estrutural e Molecular, Hospital das Clínicas, Faculdade de Medicina

Resultados de Busca

Agora exibindo 1 - 10 de 20
  • bookPart
    Nódulos mamários na adolescência
    (2021) RUIZ, Carlos Alberto; MALHONE, Carolina; ALMEIDA, José Alcione Macedo
  • bookPart
    Tumor phyllodes da mama: diagnóstico e tratamento
    (2016) RUIZ, Carlos Alberto; TORRES, Ana Paula; MAESAKA, Jonathan; FILASSI, José Roberto
  • bookPart
    Processos inflamatórios da mama na adolescência
    (2021) RICCI, Marcos Desidério; RUIZ, Carlos Alberto; ALMEIDA, José Alcione Macedo
  • article 2 Citação(ões) na Scopus
    Management of early-stage triple-negative breast cancer: recommendations of a panel of experts from the Brazilian Society of Mastology
    (2022) FREITAS-JUNIOR, Ruffo; OLIVEIRA, Vilmar Marques de; FRASSON, Antonio Luiz; CAVALCANTE, Francisco Pimentel; MANSANI, Fabio Postiglione; MATTAR, Andre; ZERWES, Felipe Pereira; FREITAS, Adriana Magalhaes de Oliveira; SOUZA, Alessandra Borba Anton de; DAMIN, Andrea P.; SANTOS, Annamaria Massahud Rodrigues dos; RUIZ, Carlos Alberto; LUCENA, Clecio Enio Murta de; MILLEN, Eduardo Camargo; BAGNOLI, Fabio; ANDRADE, Felipe; RODRIGUES, Frank Lane Braga; FACINA, Gil; NOVITA, Guilherme; PEDRINI, Jose Luiz; GUARA, Jose Pereira; SOARES, Leonardo Ribeiro; CORPA, Marcus Vinicius de Nigro; PASSOS, Mauro; FERREIRA, Nancy Cristina Ferraz de Lucena; FREITAS, Nilceana Maya Aires; MACHADO, Rafael Henrique Szymanski; AMARAL, Roberto Kepler da Cunha; REINERT, Tomas; BUDEL, Vinicius Milani
    Background Triple-negative breast cancer (TNBC) is a heterogenous subtype involving different patterns of behavior and clinical course, demanding a complex, individualized sequence of treatment. The knowledge and attitudes of the affiliated members of the Brazilian Society of Mastology regarding TNBC were evaluated and a consensus regarding management and treatment was reached. Methods Affiliates completed a survey involving 44 objective questions. In addition, a specialist meeting was held with 27 experts and 3 ad hoc consultants. The panelists completed the survey before and after brainstorming. Answers achieving 70% of agreement were considered consensual. The chi-square test was used to compare answers between panelists and affiliates and the Kappa coefficient to calculate agreement. Results Consensus among the panelists increased from 26 (59.1%) to 32 questions (72.7%) following brainstorming (p = 0.17), including 7/10 questions on systemic treatment. Among the affiliates, consensus was achieved for 24 questions (54.5%), resulting in moderate agreement (kappa = 0.445). Neoadjuvant chemotherapy should be indicated for almost all cases (except cT1a-b N0) and should include platinum agents. When indicated, immunotherapy is part of the standard of care. The panel reaffirmed the concept of no ink on tumor as indicative of adequate margins and the possibility of sentinel lymph node biopsy for cN1 patients who become cN0 following neoadjuvant therapy. Controversies remain on combining immunotherapy with capecitabine/olaparib in pertinent cases. Conclusion Expert consensus was achieved for > 70% of the questions, with moderate agreement between panelists and affiliates. Educational interventions on systemic breast cancer treatment affected decision-making in 60% of the questions.
  • bookPart
    Nódulo mamário
    (2013) RUIZ, Carlos Alberto; MAESAKA, Jonathan Yugo; FILASSI, José Roberto; BARACAT, Edmund Chada
  • bookPart
    Anomalias do desenvolvimento mamário
    (2021) RUIZ, Carlos Alberto; REIS, Yedda Nunes; ALMEIDA, José Alcione Macedo
  • article 2 Citação(ões) na Scopus
    Evaluation of frozen-section analysis of surgical margins in the treatment of breast cancer
    (2012) NOVITA, G.; FILASSI, J. R.; RUIZ, C. A.; RICCI, M. D.; PINCERATO, K. M.; OLIVEIRA FILHO, H. R. de; SOARES JR., J. M.; BARACAT, E. C.
    Objective: To evaluate surgical margins in cases of ductal carcinoma through a histopathological exam using frozen sections. Materials and Methods: Retrospective study encompassing 242 conservative surgeries, 179 of which included intraoperative frozensection histopathology and 63 intraoperative nonfreezing techniques (macroscopy/gross examination and cytology). The results of such analyses were compared with those of the histology processing following paraffin embedment and hematoxylin and eosin (H & E) staining. A margin was deemed free when the distance between the tumor and the surgical border was equal to or greater than two millimeters. The factors given consideration for possibly affecting the results were: age, surgical aspects (skin removal and widening of surgical margins), histopathological findings (size, affected lymph nodes, and angiolymphatic invasion), and extensive intraductal and immunohistochemical components (estrogen, progesterone, Ki-67, and HER-2 receptors). In the statistical analyses, the chi-square test was used and negative predictive values were calculated. Results: The negative predictive values were 87.1% and 79.3% for frozen and nonfrozen sections, respectively. There was no significant difference between the two groups (p = 0.14). The factors under consideration had no influence on the results of the intraoperative exam of the margins. Conclusion: The present study allowed to conclude that the intraoperative exam of the surgical margins by frozen section is not superior to a macroscopy and / or cytology exam.
  • bookPart
    Cistos
    (2019) MAESAKA, Jonathan Yugo; RUIZ, Carlos Alberto
  • article 1 Citação(ões) na Scopus
    Management of benign and suspicious breast lesions during the coronavirus disease pandemic: recommendations for triage and treatment
    (2020) PURCINO, Flavia Abranches Corsetti; RUIZ, Carlos Alberto; SORPRESO, Isabel C. E.; COSTA, Ana Maria Massad; SOARES-JUNIOR, Jose Maria; BARACAT, Edmund Chada; FILASSI, Jose Roberto
  • bookPart
    Doenças Benignas da Mama
    (2016) RUIZ, Carlos Alberto; PIATO, José Roberto Morales; MAESAKA, Jonathan Yugo; FREITAS, Gabriela Boufelli de; RICCI, Marcos Desidério; FILASSI, José Roberto