BRUNO SALOMAO HIRSCH

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  • article 2 Citação(ões) na Scopus
    Homemade endoscopic vacuum therapy device for the management of transmural gastrointestinal defects
    (2023) MOURA, Diogo Turiani Hourneaux de; HIRSCH, Bruno Salomao; MCCARTY, Thomas R.; SANTOS, Marcos Eduardo dos; GUEDES, Hugo Goncalo; GOMES, Guilherme Francisco; MEDEIROS, Flaubert Sena de; MOURA, Eduardo Guimaraes Hourneaux de
    ObjectivesEndoscopic vacuum therapy (EVT) possesses a unique mechanism of action providing a less invasive alternative for the management of transmural gastrointestinal defects (TGID). This study evaluates the efficacy and safety of a novel homemade EVT (H-EVT) for the treatment of TGID. MethodsRetrospective multicenter study including patients who underwent H-EVT for TGID between January 2019 and January 2022. Main outcomes included technical and clinical success as well as safety outcomes. Subgroup analyses were included by defect location and classification. Logistic regression analyses were performed to determine predictors for successful closure. ResultsA total of 144 patients were included. Technical success was achieved in all patients, with clinical success achieved in 88.89% after a mean of 3.49 H-EVT exchanges over an average of 23.51 days. After excluding 10 cases wherein it was not possible to achieve negative pressure, successful closure occurred in 95.52% of patients. Time to clinical success was less for defects caused by endoscopic (hazard ratio [HR] 0.63; 95% confidence interval [CI] 0.33-1.20) compared to surgical procedures and for patients with simultaneous intracavitary and intraluminal H-EVT placement (HR 0.70; 95% CI 0.55-0.91). Location and classification of defect did not impact clinical success rate. Simultaneous placement of both an intraluminal and intracavitary H-EVT (odds ratio 3.08; 95% CI 1.19-7.95) was a significant predictor of clinical success. Three device-related adverse events (2.08%) occurred. ConclusionsThe use of the H-EVT is feasible, safe, and effective for the management of TGID.
  • article 2 Citação(ões) na Scopus
    Sequential Endoscopic Therapies for Treatment of Complex Gastrointestinal Transmural Leak Following Bariatric Surgery
    (2022) BESTETTI, Alexandre Moraes; SANTO, Marco Aurelio; TRASOLINI, Roberto Paolo; FREITAS JUNIOR, Joao Remi de; HIRSCH, Bruno Salomao; MOURA, Eduardo Guimaraes Hourneaux de; MOURA, Diogo Turiani Hourneaux de
  • article 7 Citação(ões) na Scopus
    Low-cost modified endoscopic vacuum therapy using a triple-lumen tube allows nutrition and drainage for treatment of an early post-bariatric surgery leak
    (2022) MOURA, Diogo Turiani Hourneaux de; HIRSCH, Bruno Salomao; BOGHOSSIAN, Mateus Bond; MEDEIROS, Flaubert Sena de; MCCARTY, Thomas R.; THOMPSON, Christopher C.; MOURA, Eduardo Guimaraes Hourneaux de
  • article 14 Citação(ões) na Scopus
    Pain relief in chronic pancreatitis: endoscopic or surgical treatment? a systematic review with meta-analysis
    (2021) MENDIETA, Pastor Joaquin Ortiz; SAGAE, Vitor Massaro Takamatsu; RIBEIRO, Igor Braga; MOURA, Diogo Turiani Hourneaux de; SCATIMBURGO, Maria Vitoria Cury Vieira; HIRSCH, Bruno Salomao; ROCHA, Rodrigo Silva de Paula; VISCONTI, Thiago Arantes de Carvalho; SANCHEZ-LUNA, Sergio A.; BERNARDO, Wanderley Marques; MOURA, Eduardo Guimaraes Hourneaux de
    Background and aims Pain is one of the consequences of chronic pancreatitis (CP) that has the greatest impact on the quality of life of patients. Endoscopic and surgical interventions, by producing a decrease in intraductal pancreatic pressure, can provide pain relief. This is the first systematic review that includes only randomized clinical trials (RTCs) comparing outcomes in the short-term (less than 2 years) and long-term (more than 2 years) between these two types of interventions. Material and methods A comprehensive search of multiple electronic databases to identify RTCs comparing short and long-term pain relief, procedural complications, and days of hospitalization between endoscopic and surgical interventions was performed following the PRISMA guidelines. Results Three RCTs evaluating a total of 199 patients (99 in the endoscopy group and 100 in the surgery group) were included in this study. Surgical interventions provided complete pain relief, with statistical difference, in the long-term (16,4% vs 35.7%; RD 0.19; 95% CI 0.03-0.35; p = 0.02; I2 = 0%), without significant difference in short-term (17.5% vs 31.2%; RD 0.14; 95% CI -0.01-0.28; p = 0.07; I2 = 0%) when compared to endoscopy. There was no statistical difference in short-term (17.5% vs 28.1%; RD 0.11; 95% CI -0.04-0.25; p = 0.15; I2 = 0%) and long-term (34% vs 41.1%; RD 0.07; 95% CI -0.10-0.24; p = 0.42; I2 0%) in partial relief of pain between both interventions. In the short-term, both complications (34.9% vs 29.7%; RD 0.05; 95% CI -0.10-0.21; p = 0.50; I2 = 48%) and days of hospitalization (MD -1.02; 95% CI -2.61-0.58; p = 0.21; I2 = 0%) showed no significant differences. Conclusion Surgical interventions showed superior results when compared to endoscopy in terms of complete long-term pain relief. The number of complications and length of hospitalization in both groups were similar.
  • conferenceObject
    FLEXIBLE ENDOSCOPIC APPROACH VERSUS NONFLEXIBLE ENDOSCOPIC THERAPIES FOR THE MANAGEMENT OF ZENKER'S DIVERTICULUM: A SYSTEMATIC REVIEW AND META-ANALYSIS
    (2023) AGUIRRE, Diegocadena; HIRSCH, Bruno Salomao; OLIVEIRA, Guilherme Henrique Peixoto de; LANDIM, Davi; NUNES, Felipe; BERNARDO, Wanderley; GONZALEZ, Juan; SASSO, Joao Guilherme Ribeiro Jordao; MOURA, Eduardo De
  • article 9 Citação(ões) na Scopus
    Endoscopic Band Ligation Versus Argon Plasma Coagulation in the Treatment of Gastric Antral Vascular Ectasia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
    (2021) HIRSCH, Bruno Salomao; RIBEIRO, Igor Braga; FUNARI, Mateus Pereira; MOURA, Diogo Turiani Hourneaux de; MATUGUMA, Sergio Eiji; SANCHEZ-LUNA, Sergio A.; MANCINI, Fabio Catache; OLIVEIRA, Guilherme Henrique Peixoto de; BERNARDO, Wanderley Marques; MOURA, Eduardo Guimaraes Hourneaux de
    Background/Aims: Argon plasma coagulation (APC) is the most commonly used endoscopic treatment for gastric antral vascular ectasia (GAVE). Endoscopic band ligation (EBL) has emerged as an alternative therapy. Our goal was to evaluate the feasibility, efficacy, and safety of APC and EBL for the treatment of GAVE. This is the first systematic review that included only randomized controlled trials (RCTs) on this topic. Methods: A comprehensive search was performed using electronic databases to identify RCTs comparing APC and EBL for the treatment of GAVE following the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines. Results: Four RCTs were included, with a total of 204 patients. EBL was related to higher endoscopic eradication rates risk difference [RD], 0.29; 95% confidence interval [CI] [0.14, 0.44]; I-2=0%) and less bleeding recurrence than APC (RD, 0.29; 95% CI [0.15, 0.44]; I-2=0%). Patients treated with EBL required fewer blood transfusions (mean difference [MD], 1.49; 95% CI [0.28, 2.71]; I-2=96%) and hospitalizations (MD, 0.29; 95% CI [0.19, 0.39]; I-2=0%). The number of sessions required for the obliteration of lesions was higher with APC. There was no difference in the incidence of adverse events. Conclusions: EBL is superior to APC in the treatment of GAVE in terms of endoscopic eradication rates, recurrence of bleeding, and transfusion requirements.
  • article
    Chronic Menetrier disease leading to gastric cancer in youth
    (2023) HIRSCH, Bruno Salomao; CARDOSO, Silvia R.; BABA, Elisa R.; MOURA, Diogo T. H. de; GONCALVES, Manoel Ernesto P.; ROCHA, Rodrigo S. de P.; MOURA, Eduardo G. H. de
  • conferenceObject
    ENDOSCOPIC VERSUS RADIOLOGIC GASTROSTOMY FOR ENTERAL FEEDING: A SYSTEMATIC REVIEW AND META-ANALYSIS
    (2023) SANTOS, Evellin dos; OLIVEIRA, Guilherme Henrique Peixoto de; MOURA, Diogo De; HIRSCH, Bruno Salomao; BERNARDO, Wanderley; MOURA, Eduardo De
  • article 5 Citação(ões) na Scopus
    Long-term endoscopic follow-up after closure of a post-bariatric surgery fistula with a cardiac septal defect occluder
    (2022) MOURA, Diogo Turiani Hourneaux de; BOGHOSSIAN, Mateus Bond; HIRSCH, Bruno Salomao; MCCARTY, Thomas R.; BAPTISTA, Alberto Jose; MOURA, Eduardo Guimaraes Hourneaux de
  • article 1 Citação(ões) na Scopus
    Role of cholangioscopy and therapeutic options in complex anastomotic strictures after liver transplantation
    (2022) FUNARI, Mateus Pereira; HIRSCH, Bruno Salomao; FRANZINI, Tomazo Prince; MOURA, Diogo Turiani Hourneaux de; MIRANDA NETO, Antonio Afonso; MCCARTY, Thomas R.; MOURA, Eduardo Guimaraes Hourneaux de