DANIEL TAVARES DE REZENDE
Projetos de Pesquisa
Unidades Organizacionais
15 resultados
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Agora exibindo 1 - 10 de 15
- COMPARATION BETWEEN DIFFERENT METHODS OF SURVEILLANCE OF DYSPLASTIC LESIONS IN PATIENTS WIHT ULCERATIVE COLITIS AND CROHN'S DISEASE: SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CLINICAL TRIALS(2019) RESENDE, Ricardo H.; BERNARDO, Wanderlei M.; MARCO, Michele O. De; REZENDE, Daniel T.; MOTA, Raquel Cristina L.; BRUNALDI, Vitor O.; FURUYA, Carlos K.; ISHIDA, Robson K.; KUGA, Rogerio; MOURA, Eduardo G. de
- Magnifying chromoendoscopy is a reliable method in the selection of rectal neoplasms for local excision(2023) KIMURA, C. M. S.; KAWAGUTI, F. S.; HORVAT, N.; NAHAS, C. S. R.; MARQUES, C. F. S.; PINTO, R. A.; REZENDE, D. T. de; SEGATELLI, V.; SAFATLE-RIBEIRO, A. V.; JUNIOR, U. R.; MALUF-FILHO, F.; NAHAS, S. C.Purpose Adequate staging of early rectal neoplasms is essential for organ-preserving treatments, but magnetic resonance imaging (MRI) frequently overestimates the stage of those lesions. We aimed to compare the ability of magnifying chromoendoscopy and MRI to select patients with early rectal neoplasms for local excision. Methods This retrospective study in a tertiary Western cancer center included consecutive patients evaluated by magnifying chromoendoscopy and MRI who underwent en bloc resection of nonpedunculated sessile polyps larger than 20 mm, laterally spreading tumors (LSTs) >= 20 mm, or depressed-type lesions of any size (Paris 0-IIc). Sensitivity, specificity, accuracy, and positive and negative predictive values of magnifying chromoendoscopy and MRI to determine which lesions were amenable to local excision (i.e., <= T1sm1) were calculated. Results Specificity of magnifying chromoendoscopy was 97.3% (95% CI 92.2-99.4), and accuracy was 92.7% (95% CI 86.7-96.6) for predicting invasion deeper than T1sm1 (not amenable to local excision). MRI had lower specificity (60.5%, 95% CI 43.4-76.0) and lower accuracy (58.3%, 95% CI 43.2-72.4). Magnifying chromoendoscopy incorrectly predicted invasion depth in 10.7% of the cases in which the MRI was correct, while magnifying chromoendoscopy provided a correct diagnosis in 90% of the cases in which the MRI was incorrect (p = 0.001). Overstaging occurred in 33.3% of the cases in which magnifying chromoendoscopy was incorrect and 75% of the cases in which MRI was incorrect. Conclusion Magnifying chromoendoscopy is reliable for predicting invasion depth in early rectal neoplasms and selecting patients for local excision.
- THE ROLE OF THE ENDOSCOPIC BALLOON DILATION OF THE MAJOR PAPILLA IN MANAGING COMMON BILE DUCT STONES: A COMPREHENSIVE SYSTEMATIC REVIEW AND META-ANALYSIS(2019) MATSUBAYASHI, Carolina O.; BERNARDO, Wanderlei M.; MARCO, Michele O. De; RESENDE, Ricardo H.; REZENDE, Daniel T.; MOTA, Raquel Cristina L.; BRUNALDI, Vitor O.; LUZ, Gustavo O.; FRANZINI, Tomazo; MOURA, Eduardo G. de
- Peroral endoscopic myotomy (POEM): a comparative study between Chagasic and idiopathic achalasia(2020) FARIAS, Galileu F. A.; MOURA, Diogo T. H. de; MOURA, Eduardo T. H. de; REZENDE, Daniel T. de; HATHORN, Kelly E.; NASI, Ary; QUEIROZ, Natalia S. F.; MOURA, Eduardo G. H. deBackground and study aims Achalasia can be classified as either primary (idiopathic) achalasia or secondary achalasia, which is a consequence of another systemic disease. Peroral endoscopic myotomy (POEM) is an effective and safe treatment for achalasia. We evaluated the efficacy and safety of POEM in patients with Chagasic achalasia compared to idiopathic achalasia. Patients and methods We evaluated POEM procedures performed at a single institution from November 2016 to January 2018. Demographic data, Eckardt score, lower esophageal sphincter (LES) pressure, body mass index, post-operative erosive esophagitis, adverse events, length of hospital stay, and procedure-related parameters were analyzed. Results Fifty-one patients underwent POEM as a treatment for achalasia in this period (20 patients with Chagasic and 31 with Idiopathic etiology). The overall clinical success rate was 92.1 %, with no statistical difference between groups (90 % in the Chagasic group vs. 93.5 % in the Idiopathic group, P = 0.640). Both groups had significant reduction in Eckardt score and in LES pressure, and increase in bodey mass index (BMI) at 1-year follow-up. There was no statistical difference between groups regarding Eckardt score ( P = 0.439), LES pressure (p = 0.507), BMI ( P = 0.254), post erosive esophagitis (35 % vs. 38.7 %, P = 0.789), adverse events (30 % vs. 12 %, P = 0.163,) length of hospital stay (3.75 days vs. 3.58 days, P = 0.622), and operative time (101.3 min vs. 99.1 min, P = 0.840). Conclusion POEM is an effective and safe treatment for patients with achalasia. There is no difference in POEM outcomes for those patients with Chagasic or Idiopathic achalasia.
- ENDOSCOPIC FINDINGS IN SEVERE YELLOW FEVER PATIENTS PRESENTING WITH ACUTE UPPER GASTROINTESTINAL BLEEDING: A RETROSPECTIVE CASE SERIES STUDY(2019) GALETTI, Facundo; FARIAS, Galileu F.; MARTINS, Rafael K.; CORONEL, Martin A.; REZENDE, Daniel T.; ROCHA, Rodrigo S.; MOURA, Diogo T. de; BRUNALDI, Vitor O.; HO, Yeh-Li; BABA, Elisa; MOURA, Eduardo G. de
- Endoscopic dual therapy for giant peptic ulcer hemorrhage(2018) RIBEIRO, Igor Braga; REZENDE, Daniel Tavares; MADRUGA NETO, Antonio Coutinho; IDE, Edson; FURUYA, Carlos Kiyoshi; MOURA, Diogo Turiani Hourneaux De; MOURA, Eduardo Guimaraes Hourneaux De
conferenceObject RISK FACTORS FOR STENOSIS AFTER ENDOSCOPIC SUBMUCOSAL DISSECTION OF LARGE LESIONS OF THE RECTUM(2021) REZENDE, Daniel T.; KAWAGUTI, Fabio S.; MARTINS, Bruno; SAFATLE-RIBEIRO, Adriana V.; NAHAS, Caio Sergio R.; MARQUES, Carlos F.; POMBO, Amanda A.; SANTOS, Alisson L.; BRAGHIROLI, Oddone F.; RIBEIRO, Ulysses; NAHAS, Sergio C.; MALUF-FILHO, Fauze- Argon plasma coatmlation alone versus argon plasma coagulation plus full-thickness endoscopic suturing to treat weight regain after Roux-en-Y gastric bypass: a prospective randomized trial (with videos)(2020) BRUNALDI, Vitor Ottoboni; FARIAS, Galileu Ferreira Ayala; REZENDE, Daniel Tavares de; CAIRO-NUNES, Gabriel; RICCIOPPO, Daniel; MOURA, Diogo Turiani Hourneaux de; SANTO, Marco Aurelio; MOURA, Eduardo Guimaraes Hourneaux deBackground and Aims: A significant number of patients regain weight after Roux-en-Y gastric bypass. Ablation with argon plasma coagulation (APC) plus endoscopic full-thickness suturing (FTS-APC) and ablation alone have been reported for treating weight regain when associated with gastrojejunostomy (GJ) dilation. However, comparative controlled data are still lacking. Methods: This was a pilot single-center open-label randomized trial comparing the effectiveness and safety of APC alone versus FTS-APC for transoral outlet reduction. Patients with at least 20% weight regain from the nadir, and GJ >= 15 mm were considered eligible. The primary outcome was percentage total weight loss (%TWL) at 12 months. Secondary outcomes were the incidence of adverse events, amelioration of metabolic laboratory parameters, and improvement in quality of life and eating behavior. Results: Forty patients meeting the eligibility criteria were enrolled from October 2017 to July 2018. Technical and clinical success rates were similar between the groups. At 12 months, the mean %TWL was 8.3% +/- 5.5% in the APC alone group versus 7.5% +/- 7.7% in the Fl S-APC group (P = .71). The pre-revisional % solid gastric retention at 1 hour positively correlated with the probability of achieving >= 10% TWL at 12 months. Both groups experienced significant reductions in low-density lipoprotein and triglyceride levels at 12 months, and improvement in eating behavior and quality of life at 3 months. There were 2 cases of stenoses (1 from each group), which were successfully treated with endoscopic balloon dilation. Conclusion: APC alone is similar to FTS-APC in terms of technical and clinical outcomes within 1 year of followup.
- FULL-THICKNESS ENDOSCOPIC SUTURING PLUS APC VERSUS APC ALONE TO TREAT WEIGHT REGAIN FOLLOWING ROUX-EN-Y GASTRIC BYPASS: AN INTERIM ANALYSIS OF A RANDOMIZED CONTROLLED TRIAL(2019) BRUNALDI, Vitor O.; FARIAS, Galileu F.; REZENDE, Daniel T.; NUNES, Gabriel C.; MOURA, Diogo T. de; NETO, Manoel Galvao; SOUZA, Thiago F.; RICCIOPPO, Daniel; SANTO, Marco Aurelio; MOURA, Eduardo G. de
- Impact of a Routine Colorectal Endoscopic Submucosal Dissection in the Surgical Management of Nonmalignant Colorectal Lesions Treated in a Referral Cancer Center(2023) KAWAGUTI, Fabio S.; KIMURA, Cintia Mayumi Sakurai; MOURA, Renata Nobre; SAFATLE-RIBEIRO, Adriana Vaz; NAHAS, Caio Sergio Rizkallah; MARQUES, Carlos Frederico Sparapan; REZENDE, Daniel Tavares de; SEGATELLI, Vanderlei; COTTI, Guilherme Cutait de Castro; RIBEIRO JUNIOR, Ulysses; MALUF-FILHO, Fauze; NAHAS, Sergio CarlosBACKGROUND: Recent data show an increasing number of abdominal surgeries being performed for the treatment of nonmalignant colorectal polyps in the West but in settings in which colorectal endoscopic submucosal dissection is not routinely performed. This study evaluated the number of nonmalignant colorectal lesions referred to surgical treatment in a tertiary cancer center that incorporated magnification chromoendoscopy and endoscopic submucosal dissection as part of the standard management of complex colorectal polyps. OBJECTIVE: The study aimed to estimate the number of patients with nonmalignant colorectal lesions referred to surgical resection at our institution after the standardization of routine endoscopic submucosal dissection and to describe outcomes for patients undergoing colorectal endoscopic submucosal dissection. DESIGN: Single-center retrospective study from a prospectively collected database of endoscopic submucosal dissections and colorectal surgeries performed between January 2016 and December 2019. SETTING: Reference cancer center. PATIENTS: Consecutive adult patients with complex nonmalignant colorectal polyps were included. INTERVENTIONS: Patients with nonmalignant colorectal polyps were treated by endoscopic submucosal dissection or surgery (elective colectomy, rectosigmoidectomy, low anterior resection, or proctocolectomy). MAIN OUTCOMES MEASURES: The primary outcome measure was the percentage of patients referred to colorectal surgery for nonmalignant lesions. RESULTS: In the study period, 1.1% of 825 colorectal surgeries were performed for nonmalignant lesions, and 97 complex polyps were endoscopically removed by endoscopic submucosal dissection. The en bloc, R0, and curative resection rates of endoscopic submucosal dissection were 91.7%, 83.5%, and 81.4%, respectively. The mean tumor size was 59 (SD 37.8) mm. Perforations during endoscopic submucosal dissection occurred in 3 cases, all treated with clipping. One patient presented with a delayed perforation 2 days after the endoscopic resection and underwent surgery. The mean follow-up period was 3 years, with no tumor recurrence in this cohort. LIMITATIONS: Single-center retrospective study. CONCLUSIONS: A workflow that includes assessment of the lesions with magnification chromoendoscopy and resection through endoscopic submucosal dissection can lead to a very low rate of abdominal surgery for nonmalignant colorectal lesions.