BENOIT JACQUES BIBAS
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/61 - Laboratório de Pesquisa em Cirurgia Torácica, Hospital das Clínicas, Faculdade de Medicina
LIM/61 - Laboratório de Pesquisa em Cirurgia Torácica, Hospital das Clínicas, Faculdade de Medicina
63 resultados
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- Great expectations(2012) PEGO-FERNANDES, Paulo Manuel; BIBAS, Benoit Jacques
- Impact of gastroesophageal reflux in the pathogenesis of tracheal stenosis(2020) CARDOSO, Paulo Francisco Guerreiro; MINAMOTO, Helio; BIBAS, Benoit Jacques; PEGO-FERNANDES, Paulo ManuelBenign airway stenosis is a multifactorial and heterogeneous disease often occurring after tracheal intubation. Despite the frequent finding of pathological gastroesophageal reflux (GER) in benign tracheal stenosis, the cause-and-effect relationship between these two entities and its impact on the outcome of the stenosis itself have not been established. The altered ventilatory dynamics caused by an increased thoracoabdominal pressure gradient in such patients has been proposed as a central cause. The presence of GER in a setting of microaspiration can also induce changes in the local collagen proliferation response, as well as in the local microbiome of the tracheal stenosis site, which may potentially cause and enhance the harm imposed to the already diseased tracheal wall. Diagnosis of GER remains underestimated in the general population, thus making its accurate detection and treatment in central airway stenosis a matter of investigation. The high prevalence of GER in tracheal stenosis patients often occurs in the absence of typical upper digestive signs and symptoms, therefore requiring an objective assessment using a 24-hour ambulatory esophageal pH/impedance study that has shown abnormal results in more than half the patients. The impact of the treatment of GER in patients with benign tracheal has been scarcely reported. Our group showed recently that the surgical control of GER through laparoscopic fundoplication in selected patients with tracheal stenosis can improve substantially the chance of resolution of the tracheal stenosis as opposed to the medical management with high dose proton pump inhibitors. This chapter describes the impact of GER in the pathogenesis of tracheal stenosis with a focus on its mechanisms, diagnosis and treatment strategy.
- Hemangioma of the Rib(2011) ABRAO, Fernando Conrado; TAMAGNO, Mauro; CANZIAN, Mauro; FERNANDEZ, Angelo; BIBAS, Jacques; FERNANDES, Paulo Manuel Pego; JATENE, Fabio BiscegliAn asymptomatic 48-year-old woman presented to our hospital with a tumor of the rib incidentally diagnosed on a chest roentgenogram. The patient was investigated and underwent tumor resection of the chest wall. The pathologic study revealed that it was cavernous hemangioma. This tumor of the bone is a distinctly uncommon benign vascular tumor, generally occurring in the spine or skull. Hemangiomas involving the rib are even more rare, with only 22 cases described in the literature. However, we suggest that this tumor of the rib should be considered in the differential diagnosis, principally in asymptomatic patients. (Ann Thorac Surg 2011;91:595-6) (C) 2011 by The Society of Thoracic Surgeons
- The burden of tracheal stenosis and tracheal diseases health-care costs in the 21st century(2020) BIBAS, Benoit Jacques; CARDOSO, Paulo Francisco Guerreiro; HOETZENECKER, Konrad
article 0 Citação(ões) na Scopus Healthcare systems: what do we want?(2011) PEGO-FERNANDES, Paulo Manuel; BIBAS, Benoit Jacques- Impact of fundoplication for gastroesophageal reflux in the outcome of benign tracheal stenosis(2019) BIANCHI, Edno Tales; CARDOSO, Paulo Francisco Guerreiro; MINAMOTO, Helio; BIBAS, Benoit Jacques; SALATI, Michele; PEGO-FERNANDES, Paulo ManuelObjective: This study focuses on the impact of antireflux surgery in the outcome of tracheal stenosis. Methods: We performed a retrospective study including patients with benign tracheal stenosis who underwent esophageal manometry and dual-probe 24-hour ambulatory esophageal pH study. Patients with an abnormal pH study were managed with laparoscopic modified Nissen fundoplication or medically (omeprazole 80 mg/d, orally). Patients with normal pH study results were observed. After a 24-month follow-up, the outcome was considered satisfactory if tracheal stenosis could be managed by resection and there was no need for further dilatation or definitive decannulation. The management groups were compared using propensity score matching. Results: A total of 175 patients were included. Abnormal pH study results were found in 74 patients (42.3%), and 12.6% of patients had typical gastroesophageal reflux symptoms. Follow-up was completed in 124 patients (20 had fundoplication, 32 received omeprazole, and 72 were observed). After propensity score matching, the outcome of tracheal stenosis in the fundoplication group was similar to that of the observation group (odds ratio, 1; P = .99) and better than that of the omeprazole group (odds ratio, 5.31; P = .03). The observation (no gastroesophageal reflux) group had a better outcome of stenosis than those treated with omeprazole (odds ratio, 3.54; P = .02). Conclusions: The outcome of the airway stenosis was superior after laparoscopic fundoplication compared with medical treatment with omeprazole and was similar to the outcome of patients without gastroesophageal reflux. A prospective randomized trial is warranted.
- Robotic thoracic surgery for resection of thymoma and tumors of the thymus: technical development and initial experience(2020) TERRA, Ricardo Mingarini; MILANEZ-DE-CAMPOS, Jose Ribas; HADDAD, Rui; TRINDADE, Juliana Rocha Mol; LAURICELLA, Leticia Leone; BIBAS, Benoit Jacques; PEGO-FERNANDES, Paulo ManuelObjective: To evaluate the results of resection of tumors of the thymus by robotic thoracic surgery, analyzing the extent of resection, postoperative complications, time of surgery, and length of stay. Methods: Retrospective study from a database involving patients diagnosed with a tumor of the thymus and undergoing robotic thoracic surgery at one of seven hospitals in Brazil between October of 2015 and June of 2018. Results: During the study period, there were 18 cases of resection of tumors of the thymus: thymoma, in 12; carcinoma, in 2; and carcinoid tumor, in 1; high-grade sarcoma, in 1; teratoma, in 1; and thymolipoma, in 1. The mean lesion size was 60.1 +/- 32.0 mm. Tumors of the thymus were resected with tumor-free margins in 17 cases. The median (interquartile range) for pleural drain time and hospital stay, in days, was 1 (1-3) and 2 (2-4), respectively. There was no need for surgical conversion, and there were no major complications. Conclusions: Robotic thoracic surgery for resection of tumors of the thymus has been shown to be feasible and safe, with a low risk of complications and with postoperative outcomes comparable to those of other techniques.
conferenceObject Predictors of Hospital Discharge in Cancer Patients with Pericardial Effusion Who Undergo Surgical Pericardial Drainage(2015) KAZANTZIS, Thamara; TERRA, Ricardo M.; BIBAS, Benoit J.; LAURICELLA, Leticia L.; ARAUJO, Pedro N.; DELA-VEGA, Alberto J. M.; PEGO-FERNANDES, Paulo M.bookPart Traqueostomia mediastinal anterior(2023) BIBAS, Benoit J.; SADEK, Eduardo dos Santos R.; BüHLER, Rogério BorghibookPart Correção de fístula traqueo-esofágica(2023) BIBAS, Benoit Jacques; MINAMOTO, Hélio; CARDOSO, Paulo F. G.; BINOTTO, Bruno Fernando