ADRIANA BASTOS CONFORTO

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Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/15 - Laboratório de Investigação em Neurologia, Hospital das Clínicas, Faculdade de Medicina - Líder

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  • article 23 Citação(ões) na Scopus
    Effect of a Quality Improvement Intervention on Adherence to Therapies for Patients With Acute Ischemic Stroke and Transient Ischemic Attack: A Cluster Randomized Clinical Trial
    (2019) MACHLINE-CARRION, M. Julia; SANTUCCI, Eliana Vieira; DAMIANI, Lucas Petri; BAHIT, M. Cecilia; MALAGA, German; PONTES-NETO, Octavio Marques; MARTINS, Sheila Cristina Ouriques; ZETOLA, Viviane Flumignan; NORMILIO-SILVA, Karina; FREITAS, Gabriel Rodrigues de; GORGULHO, Alessandra; CUNHA, Ricardo Santos; SANTOS, Aparecida Bernardes dos; FERREIRA, Luis Ley Gabriel; SAAD, Michele de Nardi; MACHADO, Michel Ferreira; LUNARDI, Camila; FERRAZ, Jamana Barbosa P.; OLIVEIRA, Pablo Nascimento; VICENTE, Suellen Mariane Rios; BETTGER, Janet Prvu; PAULA, Monica de; JEREMIAS, Maria da Conceicao; ROCHA, Fernanda Mota; IBIAPINA, Viviane de Sobral; ESMANHOTTO, Bruno Bertoli; KONDO, Erika; GOMES, Denilsen Carvalho; OLIVEIRA, Wellington Gondim de; LACERDA, Nair Gomes Soares; SILVA, Priscila Rodrigues e; ANDRADE, Marianna; FERREIRA, Natalia Cristina; LOPES, Renato D.; PEDREIRA, Arthur; ARAVENA, Tania Mariela Martinez; HASSELMANN, Rafaela Souza; SANTOS, Natalia Oliveira; GOES, Fernanda; PASSOS, Tissiana; PIRAS, Claudio; TALIULE, Aparecida; ZURRU, Maria Cristina; VALE, Solene Sousa; ALONZO, Claudia; PETERSON, Eric D.; BRESCACIN, Laura; GUIDO, Bibiana; CILENTI, Luciana; SENA, Luiz Rogerio; MOREIRA, Priscila Santos; GUSMAO, Rizia; CAVALCANTE, Liane; OLIVEIRA, Geane Borge de; KENNERLY, Silvia Eduara; OLIVEIRA, Andrea Guedes de; BACKSMANN, Alessandra; BERWANGER, Otavio; THEOTONIO, Joao Manoel; OSUGUE, Raphael Kazuo; GUERRA, Silvio; SILVA, Adriana Cruz Sarde da; CARVALHO, Paula Cristina Gonzaga; SANTOS, Edval Gomes dos; FARIAS, Tarsis Leonardo Almeida; AVELAR, Wagner Mauab; SANTOS, Anne Adrielle Oliveira; ALMEIDA FILHO, Alberto Cezar Santos; SOUZA, Felipe Ferreira Ribeiro de; MACHLINE-CARRION, Maria Julia; NUNES, Renata; CARVALHO, Mariana; GARCIA, Maria del Pilar Pozo; LIMA, Gonzalo; IOLI, Pablo Leonardo; GINEL, Malena; KOSLIK, Jessika Luana Alves; KLEIN, Francisco Ricardo; CLAVERIE, Carlos Santiago; CUOTO, Juan Blas Marcos; FRASQUETE, Analia; BERWANGER, Otavio; FERREIRA, Lis Campos; ALMEIDA, Andreza S.; SANTOS, Aline; ROCHA, Marcela; JURE, Lorena Vanina; KATSURAYAMA, Marilise; ESCHOYEZ, Maria Soledad; PEREIRA, Luiz Rogerio Sena; GUSMAO, Rizia Rocha Menezes; MOREIRA, Prisicla Santos; KUSTER, Gustavo Wruck; SANTUCCI, Eliana Vieira; MARTINS, Siderleny; MARTINS, Eliana Vieira do Nascimento; MALAGA, German; SORIANO, Victor Manuel Ortiz; SOUSA, Alessandro Augusto Viana e; ANGHINAH, Renato; NAKAJIMA, Karina; RUGGERO, Laisa Maia; RITT, Luiz Eduardo Fonteles; OLIVEIRA, Queila Borges de; CARRION, Mario Husek; DAMIANI, Lucas Petri; PAESE, Mari Ines; COSTA, Samanta da; GIACOMAZZI, Juliana; DONATTI, Amanda; NEUENSCHWANDER, Fernando Carvalho; MATOS, Arlete Pereira; NEUENSCHWANDER, Cristina; NETO, Ernesto Lippi; COSTA, Elisiany Mello; CASTILHO JUNIOR, Marco Antonio Mendes; TELES, Jose Mario Meira; BAHIT, Cecilia M.; ENDRIGO, Katia; COSTA, Ludmila Teodoro da; PAVANI, Pricila; MALAGA, German; NETO, Octavio Marques Pontes; ZETOLA, Viviane Flumignan; NORMILIO-SILVA, Karina; BETTGER, Janet Prvu; XIAN, Ying; LOPES, Renato Delascio; PETERSON, Eric; MACHLINE-CARRION, Maria Julia; BERWANGER, Otavio; SALLES, Antonio De; BAHIT, M. Cecilia; MALAGA, German; MARTINS, Sheila Cristina Ouriques; NETO, Octavio Marques Pontes; ZETOLA, Viviane Flumignan; GUIMARAES, Helio Penna; CAVALCANTI, Alexandre Biasi; FREITAS, Gabriel Rodrigues de; SALLES, Antonio De; GORGULHO, Alessandra; CONFORTO, Adriana; XIAN, Ying; BETTGER, Janet Prvu; LOPES, Renato Delascio; PETERSON, Eric; MACHLINE-CARRION, Maria Julia; BERWANGER, Otavio; GUIMARAES, Helio Penna; CAVALCANTI, Alexandre Biasi; MACHLINE-CARRION, Maria Julia; BAHIT, Cecilia M.; CALDERARO, Marcelo; MALAGA, German; MACHLINE-CARRION, Maria Julia; BERWANGER, Otavio; CAVALCANTI, Alexandre Biasi; LARANJEIRA, Ligia Nasi; SOARES, Rafael Marques; SILVA, Karina Normilio; BUENO, Priscila Regina; SANTUCCI, Eliana; CAMPOS, Viviane Bezerra; BULLA, Marina Lucia; RIBEIRO, Gisele Fialho Mota; GONZALES, Beatriz Pacheco; YAMASHITA, Juliana; KODAMA, Alessandra; SAMPAIO, Bruna; BARROS, Gabriel de Melo; CANDIDO, Carolina Trovarelli; JESUINO, Isabella de Andrade; ARBAIT, Tamiris; PINHEIRO, Samara; PARISOTO, Jaynne; BUSTA, Patricia; TEJADA, Virgina; DAMIANI, Lucas Petri; NAKAGAWA, Renato Hideo; BAHIT, Cecilia; ESNAOLA, Maria Marta; MALAGA, German; CABAJAL, Andre; BUSTA, Patricia; BAREA, Liselotte Menke; ANDRADE, Karina Nocelo Ferreiro de; SANTIM, Ricardo; DAMES, Jerusa; PARANHOS, Jorge Luiz da Rocha; LIMA, Gerluce Nery; MELO, Leonardo Vaz de; MARTINS, Sheila Cristina Ouriques; FLECK, Natacha; CAMARGO, Daiane Piccolotto Carvalho; OLIVEIRA, Fabiani Santos de; BRAGA, Gabriel Pereira; FREITAS, Paloma Fontes de; BAZAN, Rodrigo; ARANTES, Juliana; VIANA, Lorena Souza; ALQUERES, Rafaela; TRENTIN, Sheila; MORALES, Diego; SILVA, Beatriz Gonzales Pacheco da; FERNANDES, Maristela Thalheimer; VOIGT, Camila; MARTINS, Gladys Lentz; PAULI, Carla; ZETOLA, Viviane Flumignan; RASO, Larissa; RUBERT, Mauren Carneiro; SARAIVA, Sonia Batista; NOGUEIRA, Marcia Aparecida Camacho Kauffmann; MONTENARO, Kamilla Machado Paschoal; SANTOS, Juliana Yamashita; VELOSO, Cabo; MARTIN, Jose Fernando Vilela; BATTAGLINI, Mariana; PARISE, Viviane; BUTINHAO, Fernanda; MARTINELLI, Debora; ZANATTA, Joao Marcos de Menezes; RIBEIRO, Suzilene; TUNUCCI, Cileia Cristina Goncalves; CASTRO, Edna Donizete Rossi; JESUINO, Isabella de Andrade; DALL'ORTO, Frederico Toledo Campo; BERGO, Ricardo Reinaldo; RIBEIRO, Gislayne Rogante; SILVA, Gisele Sampaio; ALVES, Maramelia Araujo de Miranda; REGIS, Dalva; SILVA, Ilana Izidoro; SADALA, Danyelle; ROCHA, Felipe; ROCHA, Emilia Eva; BUENO, Priscila Regina Torres; ROUANET, Carolina; GALIARDI, Vivian; NARDOTO, Luiz Felipe; MERIDA, Kristel; BRAINER, Joao; RISCO, Eduardo Javier Tapia; TAHUA, Andre Aquiles Carbajal; BUSTA, Patricia; REYS, Michael; VELASQUEZ, Rafael Francisco; CAVALCANTI, Alexandre Biasi; CAHUARUPAY, Celia; CASTILLO, Diana; MONTES, Gerson Escobar; BARBOSA, Luiz Carlos Viana; VASCONCELOS, Jose Eduardo Gomes; CRUZ, Erica Maria Brandao; GONZALEZ, Leonardo Adrian; LEPERA, Sandra; PAEZ, Mauricio; MATIAS, Alet; GUIMARAES, Helio Penna; ALVA, Edwin Javier Pretell; ESNAOLA, Maria Martha; SCHIAVA, Marianela; TAGLIANI, Paula; REITERI, Romanela Carolina; GIARDINO, Daniela; EVARISTO, Eli; SANTOS, Edgar Ferreira dos; TAMBURIM, Barbara Reis; PEREIRA, Nathalia C. A.; XIAN, Ying; ROSA, Geiza Cristina Lozano Gomes da
    Key PointsQuestionCan a multifaceted quality improvement intervention increase the adherence to 10 evidence-based performance measures for patients with acute ischemic stroke and transient ischemic attack in Latin America? FindingsIn this cluster randomized clinical trial that included 1624 patients from 36 hospitals in 3 countries, hospitals in the intervention group had a composite adherence score of 85.3% for the evidence-based performance measures, and those in the control group had a score of 77.8%, a difference that was not statistically significant. In a planned secondary analysis, improvement in adherence to all 10 performance measures was greater in the intervention group than in the control group using an all-or-none approach for the outcome. MeaningIn this cohort of patients with acute ischemic stroke and transient ischemic attack, a multifaceted intervention did not demonstrate an overall improvement in adherence to evidence-based performance measures compared with standard of care, yet individual care elements improved. This cluster randomized clinical trial assesses the effect of a multifaceted quality improvement intervention compared with routine care on adherence to evidence-based therapy among patients with acute ischemic stroke and transient ischemic attack. ImportanceTranslating evidence into clinical practice in the management of acute ischemic stroke (AIS) and transient ischemic attack (TIA) is challenging, especially in low- and middle-income countries. ObjectiveTo assess the effect of a multifaceted quality improvement intervention on adherence to evidence-based therapies for care of patients with AIS and TIA. Design, Setting and ParticipantsThis 2-arm cluster-randomized clinical trial assessed 45 hospitals and 2336 patients with AIS and TIA for eligibility before randomization. Eligible hospitals were able to provide care for patients with AIS and TIA in Brazil, Argentina, and Peru. Recruitment started September 12, 2016, and ended February 26, 2018; follow-up ended June 29, 2018. Data were analyzed using the intention-to-treat principle. InterventionsThe multifaceted quality improvement intervention included case management, reminders, a roadmap and checklist for the therapeutic plan, educational materials, and periodic audit and feedback reports to each intervention cluster. Main Outcomes and MeasuresThe primary outcome was a composite adherence score for AIS and TIA performance measures. Secondary outcomes included an all-or-none composite end point of performance measures, the individual process measure components of the composite end points, and clinical outcomes at 90 days after admission (stroke recurrence, death, and disability measured by the modified Rankin scale). ResultsA total of 36 hospitals and 1624 patients underwent randomization. Nineteen hospitals were randomized to the quality improvement intervention and 17 to routine care. The overall mean (SD) age of patients enrolled in the study was 69.4 (13.5) years, and 913 (56.2%) were men. Overall mean (SD) composite adherence score for the 10 performance measures in the intervention group hospitals compared with control group hospitals was 85.3% (20.1%) vs 77.8% (18.4%) (mean difference, 4.2%; 95% CI, -3.8% to 12.2%). As a secondary end point, 402 of 817 patients (49.2%) at intervention hospitals received all the therapies that they were eligible for vs 203 of 807 (25.2%) in the control hospitals (odds ratio, 2.59; 95% CI, 1.22-5.53; P=.01). Conclusions and RelevanceA multifaceted quality improvement intervention did not result in a significant increase in composite adherence score for evidence-based therapies in patients with AIS or TIA. However, when using an all-or-none approach, the intervention resulted in improved adherence to evidence-based therapies. Trial RegistrationClinicalTrials.gov identifier: NCT02223273
  • bookPart 0 Citação(ões) na Scopus
    Non-invasive brain stimulation in post-stroke Aphasia rehabilitationand language research
    (2021) MENDONçA, L. I. Z. de; CONFORTO, A. B.
    Aphasia is significant impairment of stroke that has a major impact on quality of life. The results of speech and language therapy are often limited. Non-invasive brain stimulation (NIBS) has been proposed as an add-on intervention to aphasia treatment. This chapter focuses on the use of NIBS in language research as well as in post-stroke aphasia research and rehabilitation. © 2021 Nova Science Publishers, Inc.
  • bookPart
    Doença Cerebrovascular
    (2015) CONFORTO, Adriana Bastos; YAMAMOTO, Fábio Iuji
  • conferenceObject
    Translational neurorehabilitation in the third world
    (2015) CONFORTO, A.; ANJOS, S.; STERR, A.; ANDRADE, K. de; COHEN, L.
  • article 1 Citação(ões) na Scopus
    Behavioral and Neural Correlates of Cognitive Training and Transfer Effects in Stroke Patients (vol 11, 1048, 2020)
    (2021) MIOTTO, Eliane C.; BAZAN, Paulo R.; BATISTA, Alana X.; CONFORTO, Adriana B.; FIGUEIREDO, Eberval G.; MARTIN, Maria da Graca M.; AVOLIO, Isabella B.; AMARO, Edson; TEIXEIRA, Manoel J.
  • conferenceObject
    High resolution vessel wall magnetic resonance imaging in HIV associated vasculopathy
    (2017) KUBOTA, G. Taricani; FERREIRA, R. de Faria; FIGUEIREDO, T. Rocha; SANTOS, G. Titoneli dos; MORAIS, L. Martins Tavares Scianni; BARBOSA, B. J. Alencar Pires; YAMAMOTO, F. Iuji; GUEDES, B. Fukelmann; CONFORTO, A. Bastos
  • conferenceObject
    Decompressive neurosurgery for patients with cerebral venous thrombosis. A prospective multicenter registry (DECOMPRESS2)
    (2020) FERREIRA, J. M.; AARON, S.; KAMMEN, M. Sanchez van; CONFORTO, A.; ARAUZ, A.; CARVALHO, M.; MASJUAN, J.; SHARMA, V. K.; UYTTENBOOGAART, M.; WERRING, D.; BAZAN, R.; MOHINDRA, S.; PUTAALA, J.; WEBER, J.; SOUSA, D.; CANHAO, P.; COERT, B.; KIRUBAKARAN, P.; SINGH, P.; COUTINHO, J.; FERRO, J. M.
  • article 36 Citação(ões) na Scopus
    Association among depression, cognitive impairment and executive dysfunction after stroke
    (2012) TERRONI, Luisa; SOBREIRO, Matildes F.M.; CONFORTO, Adriana B.; ADDA, Carla C.; GUAJARDO, Valeri D.; LUCIA, Mara Cristina S. de; FRÁGUAS, Renério
    ABSTRACT The relationship between depression and cognitive impairment, frequent after stroke, is complex and has not been sufficiently elucidated. Objective: To review the relationship between post-stroke depression and cognitive impairment. Methods: We performed a PubMed database search spanning the last ten years, using the terms post-stroke depression, cognitive dysfunction, cognitive impairment and neuropsychological tests. Our target studies were original quantitative studies that investigated the relationship between post-stroke depression (PSD) and cognitive impairment in stroke patients. Articles published in English, Spanish, Italian and Portuguese were considered. Selection criteria were the use of neuropsychological tests to assess cognitive function, and of either instruments to diagnose major depression, or scales to assess depressive symptoms, within the first three months after stroke. Results: Six original quantitative studies fulfilled the criteria. The prevalence of PSD within the first three months after stroke ranged from 22% to 31%. Incidence ranged from 25% to 27% and was evaluated in only two studies. PSD was associated with increased cognitive impairment. Cognitive impairment was reported in 35.2% to 87% of the patients. Post-stroke cognitive deficits were reported mostly in executive function, memory, language, and speed of processing. Conclusion: Executive dysfunction and depression occur in stroke survivors, are frequently coexistent, and also associated with worse stroke prognosis. Healthcare professionals need to address and provide adequate treatment for depression and executive dysfunctions in stroke patients early in the first three months after stroke. Future studies should evaluate the efficacy of programs evaluating the early detection and treatment of PSD and executive dysfunction in stroke survivors.
  • article 4 Citação(ões) na Scopus
    Behavioral and Neural Correlates of Cognitive Training and Transfer Effects in Stroke Patients
    (2020) MIOTTO, Eliane C.; BAZAN, Paulo R.; BATISTA, Alana X.; CONFORTO, Adriana B.; FIGUEIREDO, Eberval G.; MARTIN, Maria Graca M.; AVOLIO, Isabella B.; JR, Edson Amaro; TEIXEIRA, Manoel J.
    Stroke lesions are frequently followed by cognitive impairments. Cognitive training is a non-pharmacological intervention that can promote neural compensation mechanisms and strategies to remediate cognitive impairments. The aims of this study were: (1) To investigate the cognitive performance, generalization effects, and neural correlates of semantic organization strategy training (SOST) in patients with chronic left frontoparietal stroke and healthy controls (HC); and (2) to compare the behavioral effects and neural correlates of SOST with an active control psychoeducation intervention (PI). In this randomized controlled study, all participants were randomly allocated into two groups, one group received SOST, and the other received PI intervention. Participants underwent two fMRI sessions, one prior and the other, after intervention. In each fMRI session, images were obtained during memory encoding task using a list of semantically related words. We found improved post-intervention memory performance in participants that received SOST (both patients and controls), indicated by number of words recalled, word clustering scores, and performance in a generalization task. The fMRI analysis revealed negative correlation between task performance and regions of the default-mode network. These results suggest that cognitive training using semantic organization strategy can improve episodic memory performance and promote potential functional neuroplasticity in patients with ischemic stroke lesions.
  • bookPart
    Recuperação do paciente pós-acidente vascular cerebral
    (2015) GUARDA, Suzete N. F. da; MACHADO, André G.; CONFORTO, Adriana B.