ANDRE PEDRINELLI
Projetos de Pesquisa
Unidades Organizacionais
Instituto de Ortopedia e Traumatologia, Hospital das Clínicas, Faculdade de Medicina
LIM/41 - Laboratório de Investigação Médica do Sistema Músculoesquelético, Hospital das Clínicas, Faculdade de Medicina
LIM/41 - Laboratório de Investigação Médica do Sistema Músculoesquelético, Hospital das Clínicas, Faculdade de Medicina
25 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 25
- 3D COMPUTER TOMOGRAPHY FOR MEASUREMENT OF FEMORAL POSITION IN ACL RECONSTRUCTION(2015) FERNANDES, Tiago Lazzaretti; MARTINS, Nuno Miguel Morais Fonseca; WATAI, Felipe de Andrade; NETO, Cyro Albuquerque; PEDRINELLI, Andre; HERNANDEZ, Arnaldo JoseObjective: To validate intra-and inter-class correlation coefficients of a transparent 3D-TC protocol and investigate relationships between different axial rotations. Methods: Twenty unilateral knee TCs (iSite - Philips) were evaluated by means of a transparent 3D-TC OsiriX Imaging Software (v.3.9.4), 3D MPR protocol. Mathematical model of femoral tunnel projections acquired on vertical and horizontal rotations from -20 to +20 degrees. Height (h'/H) and length (t'/T) of tunnel projections have been analyzed by the Bernard and Hertel's method. Statistics: power of study=80%, ICC, ANOVA, p<0.05 (SPSS-19). Results: Transparent 3D-TC showed high reliability of both intra-observer (h'/H= 0.941; t'/T= 0.928, p<0.001) and inter-observer (h'/H= 0.921; t'/T= 0.890, p<0.001) ICC. ACL Length (t'/T) and Height (h'/H) projections were statistically different on vertical and horizontal rotations: p=0.01 and p<0.001, respectively. Conclusion: This new transparent 3DTC protocol is an accurate and reproducible method that can be applied for ACL femoral tunnel or footprint measurement with high ICC reliability.
- Imaging Assessment of the Pubis in Soccer Players(2019) TODESCHINI, Karina; DARUGE, Paulo; BORDALO-RODRIGUES, Marcelo; PEDRINELLI, André; BUSETTO, Antonio MarcosAbstract Objective To compare the accuracy of ultrasound (US) with that of magnetic resonance imaging (MRI) in the detection of aponeurosis lesions of the rectus abdominis/adductor longus muscles, to study the characteristics of the athletes and imaging findings associated with pubalgia, and to demonstrate the importance of each method in evaluating this condition. Materials and methods The present study was conducted from 2011 to 2016 with 39 professional soccer players: 15 with pubalgia and 24 without pubalgia. Age, field position, bodymass index (BMI), weekly training load, career length, and history of thigh/knee injury and lower back pain were recorded. The following tests were performed: radiographs (anteroposterior view of the pelvis in standing and flamingo positions) to evaluate hip impingement, sacroiliac joint, and pubic symphysis instability; US to analyze the common aponeurosis of the rectus abdominis/adductor longus muscles and inguinal hernias; and MRI for pubic bone degenerative alterations and edema, and lesions in the adductor and rectus abdominis muscles and their aponeurosis. Results There was an association between pubalgia, high BMI (p = 0.032) andmuscle alterations (p < 0.001). Two patients with pubalgia had inguinal hernias and one patient with pubalgia and two controls had sports hernias. Pubic degenerative changes were frequent in both groups. Aponeurosis lesions weremore frequent in patients with pain. The US detection had 44.4% sensitivity and 100% specificity. Conclusion The evaluation of athletic pubalgia should be performed with radiography, US, and MRI. High BMI, muscle injuries, geodes, and osteophytes are findings associated with pubalgia; US has low sensitivity to detect injuries of the common aponeurosis of the rectus abdominis/adductor longus muscles.
- BILATERAL LOCALIZED PIGMENTED VILLONODULAR SYNOVITIS OF THE KNEE: CASE REPORT AND REVIEW(2018) FERNANDES, Tiago Lazzaretti; VIDEIRA, Livia Dau; SASAKI, Sandra Umeda; NATALINO, Renato Jose Mendonca; ALMEIDA, Adriano Marques de; PEDRINELLI, Andre; HERNANDEZ, Arnaldo JoseObjectives: Several cases of bilateral diffuse pigmented villonodular synovitis (PVNS) or tenosynovial giant cell tumor have been described in the literature. Nevertheless, some presentations are rare and differential diagnoses are necessary. Methods: The purpose of this study was to perform a systematic review of the literature related to PVNS and to report a rare supra-patellar bilateral and focal presentation. We performed a systematic data review in the Pubmed Clinical Queries database using MeSH and keywords related to PVNS and tenosynovial giant cell tumor. Results: Two cases of bilateral and local PVNS had been previously described, but neither was localized in the supra-patellar compartment. To our knowledge, this case report is the first to describe supra-patellar bilateral and localized PVNS of the knee. This case involves a 28-year-old woman with bilateral localized PVNS of the supra-patellar recess of the knee. MRI showed a low-signal intensity nodule in T1-and T2-weighted images. These were associated with hemosiderin pigmentation. Conclusion: The most important finding of the case reported is related to rarity and location. Histopathology analysis confirmed a rare case of hemosiderin pigmentation in the capsular nodule with internal non-pigmented villous content. Lipoma arborescens in the supra-patellar form must be ruled out as a differential diagnosis since it occurs in the same site.
- Medications and Nutritional Supplements in Athletes during the 2000, 2004, 2008, and 2012 FIFA Futsal World Cups(2015) PEDRINELLI, Andre; EJNISMAN, Leandro; FAGOTTI, Lorenzo; DVORAK, Jiri; TSCHOLL, Philippe M.Objective. To examine the use of medications and nutritional supplements among top-level male futsal players during international tournaments. Materials and Methods. This retrospective survey of the four consecutive 2000 to 2012 FIFA(Federation Internationale de Football Association) Futsal World Cup tournaments analyzes data about the use of medications and nutritional supplements by each player prior to every match. A total of 5264 reports on 1064 futsal players were collected from the 188 matches played. Results. A total of 4237 medications and 8494 nutritional supplements (0.8 and 1.6 per player per match, resp.) were prescribed, and 64% of the players used at least one type of medication over the four tournaments. The most frequently prescribed medication was nonsteroidal anti-inflammatory drugs (NSAIDs) (41.1%), whereby 45.7% of all players consumed at least one NSAID during the tournament and 27.4% did so prior to every match. Conclusions. The intake of medications, particularly of NSAIDs, is frequently high among top-level futsal players and follows a similar pattern to that found in FIFA Football World Cups. Campaigns should be instituted to understand this prescription practice by team physicians involving professional football players, with the aim to decrease its use and to prevent athletes from potential short-and long-term risks.
- Joint position statement of the International Federation of Sports Medicine (FIMS) and European Federation of Sports Medicine Associations (EFSMA) on the IOC framework on fairness, inclusion and non-discrimination based on gender identity and sex variations(2022) PIGOZZI, Fabio; BIGARD, Xavier; STEINACKER, Juergen; WOLFARTH, Bernd; BADTIEVA, Victoriya; SCHNEIDER, Christian; SWART, Jeroen; BILZON, James Lee John; CONSTANTINOU, Demitri; DOHI, Michiko; LUIGI, Luigi Di; FOSSATI, Chiara; BACHL, Norbert; LI, Guoping; PAPADOPOULOU, Theodora; CASASCO, Maurizio; RENSBURG, Dina Christina (Christa) Janse van; KAUX, Jean-Francois; ROZENSTOKA, Sandra; CASAJUS, Jose-Antonio; ZELENKOVA, Irina; AK, Emre; ULKAR, Bulent; ARROYO, Francisco; IONESCU, Anca; PEDRINELLI, Andre; MILLER, Mike; SINGLETON, Patrick; SHROFF, Malav; WEBBORN, Nick; BARRETT, James; HAMILTON, Blair; GEISTLINGER, Michael; BELTRAMI, Gianfranco; MIGLIORINI, Sergio; DIENSTBACH-WECH, Lenka; BERMON, Stephane; PITSILADIS, Yannis P.The IOC recently published its framework on fairness, inclusion and non-discrimination based on gender identity and sex variations. This framework is drafted mainly from a human rights perspective, with less consideration for medical/scientific issues. The framework places the onus for gender eligibility and classification entirely on the International Federations (IFs), even though most will not have the capacity to implement the framework. The position of no presumption of advantage is contrary to the 2015 IOC consensus. Implementation of the 2021 framework will be a major challenge for IFs that have already recognised the inclusion of trans and women athletes with differences of sexual development (DSD) using a scientific/medical solution. The potential consequences for sports that need to prioritise fairness or safety could be one of two extremes (1) exclusion of all transgender or DSD athletes on the grounds of advantage or (2) self-identification that essentially equates to no eligibility rules. Exclusion of all transgender or DSD athletes is contrary to the Olympic charter and unlawful in many countries. While having no gender eligibility rules, sport loses its meaning and near-universal support. Athletes should not be under pressure to undergo medical procedures or treatment to meet eligibility criteria. However, if an athlete is fully informed and consents, then it is their free choice to undergo carefully considered or necessary interventions for gender classification for sport to compete fairly and safely in their chosen gender. Free choice is a fundamental human right, but so is the right to fair and safe competition.
- Muscle Injury: Pathophysiology, Diagnosis, and Treatment(2022) SANTANNA, João Paulo Cortez; PEDRINELLI, André; HERNANDEZ, Arnaldo José; FERNANDES, Tiago LazzarettiAbstract Skeletal muscle tissue has the largest mass in the human body, accounting for 45% of the total weight. Muscle injuries can be caused by bruising, stretching or laceration. The current classification divides these injuries into mild, moderate and severe. The signs and symptoms of grade I lesions are edema and discomfort; grade II, loss of function, gaps and possible ecchymosis; and grade III, complete rupture, severe pain and extensive hematoma. The diagnosis can be confirmed by ultrasound, which is dynamic and cheap, but examiner dependent; and magnetic resonance imaging (MRI), which provides better anatomical definition. The initial phase of the treatment consists in protection, rest, optimal use of the affected limb, and cryotherapy. Nonsteroidal anti-inflammatory drugs (NSAIDs), ultrasound therapy, strengthening and stretching after the initial phase and range of motion without pain are used in the clinical treatment. On the other hand, surgery has precise indications: hematoma drainage and muscle-tendon reinsertion and reinforcement.
- Epidemiological study on professional football injuries during the 2011 Copa America, Argentina(2013) PEDRINELLI, André; CUNHA FILHO, Gilberto Amado Rodrigues da; THIELE, Edilson Schwansee; KULLAK, Osvaldo PangrazioOBJECTIVE: Develop an epidemiological study of injuries occurred among male professional football players during the Copa America 2011, held in Argentina. METHODS: We conducted a retrospective study of injuries sustained during the 43rd edition of the Copa America football in Argentina, in 2011. The lesions were evaluated by the medical department of the selections and reported to the CONMEBOL. The data were compiled and reported in accordance with rules established by the FIFA Medical Assessment and Research Centre (F-MARC) in 2005. RESULTS: There was a higher prevalence of lesions in the lower limbs. Thighs and knees were the most affected segments. The most frequent diagnoses were muscle injuries. The injuries were mostly minor degrees of severity and there was little difference in the prevalence of lesions according to the stages of the match, with slight predominance in the final 15 minutes. The incidence of lesions per 1,000 game hours was similar to the average found in the literature. CONCLUSIONS: The results obtained allowed us to outline a profile of the prevalence, distribution per body segment, minute in which occurred and severity of injuries in professional football players of participating teams in the Copa America 2011 in Argentina. The extreme rigor of referees may be partly attributed to the highly competitive nature of international tournaments. However, this results cannot be considered definitive because of the need to be compared to other epidemiological studies with same design using similar concepts and criteria.
- ANTEROMEDIAL OR CENTRAL ANATOMIC ACL RECONSTRUCTION? A CADAVERIC HIP-TO-TOE STUDY(2023) FERNANDES, Tiago Lazzaretti; SOUZA, Michel Oliveira; NETO, Cyro Albuquerque; ARAUJO, Paulo Henrique; PEDRINELLI, Andre; HERNANDEZ, Arnaldo JoseObjective: To compare anatomic anterior cruciate ligament (ACL) reconstruction between two tunnel positions in knees with isolated ligament tears. Methods: Anatomic ACL reconstruction was performed, from hip-to-toe, on 15 fresh cadaveric specimens. No associated lesions were created to enhance knee instability. The protocol was conducted in three states: (1) complete isolated ACL deficiency; (2) anatomic femoral and tibial anteromedial ACL reconstruction (AM REC); and (3) anatomic femoral and tibial central ACL reconstruction (Central REC). The reconstruction protocols were randomly assigned. The continuous mechanized pivot-shift test was recorded dynamically with a tracking system. Results: The Central REC group showed a smaller degree of internal rotation (0.6 & DEG; & PLUSMN; 0.3 & DEG; vs. 1.8 & DEG; & PLUSMN; 0.3 & DEG;, respectively, P < 0.05) and no difference in anterior translation (4.7 mm & PLUSMN; 0.4 mm vs. 4.5 mm & PLUSMN; 0.4 mm, respectively, P > 0.05) in the pivot-shift test, compared with the AM REC group. Conclusion: The central anatomic ACL reconstruction resulted in greater restriction of internal rotation than the anteromedial anatomic ACL reconstruction. Experimental Study on Cadaver.
- Letter to the editor entitled “fairness and scientific correctness is needed in the debate on transgender athletes”(2023) PITSILADIS, Y.; HAMILTON, B.; GEISTLINGER, M.; BERMON, S.; BIGARD, X.; MIGLIORINI, S.; WOLFARTH, B.; LUIGI, L. Di; IONESCU, A.; SCHNEIDER, C.; BACHL, N.; MILLER, M.; SHROFF, M.; SINGLETON, P.; CONSTANTINOU, D.; SWART, J.; BELTRAMI, G.; ARROYO, F.; BADTIEVA, V.; KAUX, J.-F.; ROZENšTOKA, S.; DIENSTBACH-WECH, L.; CASAJUS, J. A.; ZELEKOVA, I.; STEINACKER, J. M.; ÜLKAR, B.; PAPADOPOULOU, T.; WEBBORN, N.; CASASCO, M.; FOSSATI, C.; BARRETT, J.; BILZON, J. L. J.; DOHI, M.; LI, G.; AK, E.; PEDRINELLI, A.; PIGOZZI, F.In the joint position statement signed by members of the International Federation of Sports Medicine (FIMS) and European Federation of Sports Medicine Associations (EFSMA) on the International Olympic Committee (IOC) framework on fairness, inclusion and non-discrimination based on gender identity and sex variations, more than 35 experts proposed approaches to integrate transgender women and female athletes with differences of sex development (DSD) into elite competition (1).
- Description of an evaluation system for knee kinematics in ligament lesions, by means of optical tracking and 3D tomography,(2014) FERNANDES, Tiago Lazzaretti; RIBEIRO, Douglas Badillo; ROCHA, Diogo Cristo da; ALBUQUERQUE, Cyro; MARTINS PEREIRA, César Augusto; PEDRINELLI, André; HERNANDEZ, Arnaldo JoséObjective: To describe and demonstrate the viability of a method for evaluating knee kine matics, by means of a continuous passive motion (CPM) machine, before and after anterio cruciate ligament (ACL) injury. Methods: This study was conducted on a knee from a cadaver, in a mechanical pivot-shif simulator, with evaluations using optical tracking, and also using computed tomography. Results: This study demonstrated the viability of a protocol for measuring the rotation an translation of the knee, using reproducible and objective tools (error<0.2mm). The mech anized provocation system of the pivot-shift test was independent of the examiner an always allowed the same angular velocity and traction of 20 N throughout the movement. Conclusion: The clinical relevance of this method lies in making inferences about the in viv behavior of a knee with an ACL injury and providing greater methodological quality in futur studies for measuring surgical techniques with grafts in relatively close positions.
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