EDUARDO GUILHERME D'ALESSANDRO
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/01 - Laboratório de Informática Médica, Hospital das Clínicas, Faculdade de Medicina
LIM/01 - Laboratório de Informática Médica, Hospital das Clínicas, Faculdade de Medicina
12 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 12
bookPart Acupuntura no paciente oncológico(2019) D´ALESSANDRO, Eduardo Guilherme- Acupuncture for Climacteric-Like Symptoms in Breast Cancer Improves Sleep, Mental and Emotional Health: A Randomized Trial(2022) D'ALESSANDRO, Eduardo Guilherme; SILVA, Alexandre Valotta da; CECATTO, Rebeca Boltes; BRITO, Christina May Moran de; AZEVEDO, Raymundo Soares; LIN, Chin AnObjective: Breast cancer is the most prevalent malignant neoplasm in women. Optimal treatment frequently includes a hormonal-blockage phase maintained for 5-10 years. Pharmacologic agents used for this blockage induce many climacteric-like symptoms, which often exact a heavy toll on patients' quality of life. Acupuncture has had promising results for treating climacteric-like symptoms induced by hormonal blockage, but there is no evidence of efficacy for controlling hot flashes.Materials and Methods: This trial used acupuncture to treat the climacteric-like symptoms of patients with breast cancer, focusing on the mental, physical, and genitourinary symptoms and sleep disturbances, to determine the influence of acupuncture treatment. The randomized placebo-controlled trial, at a university-based cancer center, with blinded data collectors, compared an Acupuncture group (A), a Sham-Acupuncture group (S), and a Wait-List Control group (C). The patients were receiving tamoxifen. Group A had 10 weekly sessions of manual Acupuncture; Group S had 10 weekly sessions of Sham Acupuncture; and Group C spent 10 weeks on a Wait-List. The main outcome measures were the Beck Depression Inventory-II (BDI-II), the Pittsburgh Sleep Quality Index (PSQI), and the Menopause Rating Scale (MRS).Results: Primary analysis revealed differences among the groups' improvements in scores for the 3 questionnaires (P < 0.001), The A group had significant improvements on the BDI-II (P < 0.001), PSQI (P < 0.002), and MRS (P < 0.004) compared to the S group in a post hoc analysis.Conclusions: Acupuncture improved sleep, and mental and emotional distress symptoms induced by hormonal blockage in patients with breast cancer.
bookPart Acupuntura para o tratamento da dor(2019) TSAI, André Wan Wen; LIN, Chin An; D´ALESSANDRO, Eduardo Guilherme; HSING, Wu TubookPart Protocolo de acupuntura(2014) D'ALESSANDRO, Eduardo G.; SAUL, Maíra; SILVA, Patriciano José da; CECATTO, Rebeca BoltesbookPart Acupuntura na medicina interna(2019) D´ALESSANDRO, Eduardo Guilherme- Acupuncture for chemotherapy-induced peripheral neuropathy: a randomised controlled pilot study(2022) D'ALESSANDRO, Eduardo Guilherme; NAGY, Daniela Ribeiro Nebuloni; BRITO, Christina May Moran de; ALMEIDA, Elisangela Pinto Marinho; BATTISTELLA, Linamara Rizzo; CECATTO, Rebeca BoltesChemotherapy-induced peripheral neuropathy (CIPN) can cause loss of independence and poor quality of life (QoL) due to severe disabilities, but in spite of its importance there is still a lack of data for the management of CIPN. Acupuncture has showed promising results and may be a cost-effective option for the treatment. Objectives To evaluate the effect of acupuncture treatment on neurological symptoms of CIPN and QoL of oncological patients. Methods We performed a clinical, single-centre, randomised and controlled pilot study that involved 33 adult patients with cancer and CIPN randomised into two groups (control and acupuncture treated with 10 sessions, two times per week). Both groups were subjected to a complete physical examination and clinical assessment with National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE) Scale V.2.0, FIM Scale, European Organisation for the Research and Treatment of Cancer Quality of Life Questionnaire Core (EORTC QLQ-C30) Scale and Visual Analogue Scale for pain before and 5 weeks after treatment. Results There were no adverse events, and we found statistical differences in groups in physical (p=0.03) and function (p=0.04) domains of EORTC QLQ-C30 when comparing control and acupuncture groups. About NCI CTCAE Scale and neuropathy sensory symptoms, we found better results in acupuncture group, comparing pretreatment and post-treatment analyses (p=0.01). In control group, we have no differences after 5 weeks (p=0.11). Conclusion Although these results suggest an interesting effect of acupuncture on this patient population, the clinical significance has remained unclear. Given the tendency towards benefit and the lack of adverse effects, the authors recommend a follow-up acupuncture trial using higher follow-up time and better sample size.
bookPart Climatério(2019) BULGARELLI, Suzi Tsiomi Miyazato; D´ALESSANDRO, Eduardo GuilhermebookPart Clínica médica(2021) D´ALESSANDRO, Eduardo G.- How Do You Treat Asthma in Your Practice?(2018) SUDHAKARAN, Poovadan; HAYHOE, Simon; AUNG, Steven K. H.; BARNES, Mary Ann; CAYIR, Yasemin; D'ALESSANDRO, Eduardo G.; LIN, Chin An; PAI, Hong Jin; IMAI, Kenji; IMAI, Motoyuki; HISAJIMA, Tatsuya; IDE, Kazuki; KAWAKAMI, Koji; KIM, Yun Jin; GARCIA, Yolanda Maria
bookPart Acupuntura para o tratamento da dor(2022) TSAI, André Wan Wen; LIN, Chin Na; D´ALESSANDRO, Eduardo Guilherme; HSING, Wu Tu