GABRIEL GRIZZO CUCATO
Projetos de Pesquisa
Unidades Organizacionais
LIM/02 - Laboratório de Anatomia Médico-Cirúrgica, Hospital das Clínicas, Faculdade de Medicina
9 resultados
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Agora exibindo 1 - 9 de 9
conferenceObject PHYSICAL ACTIVITY LEVEL CHANGES AND THE OCCURRENCE OF NON-ALCOHOLIC FATTY-LIVER DISEASE: A PROSPECTIVE LONGITUDINAL FOLLOW UP STUDY(2017) BITTENCOURT, Marcio Sommer; RITTI-DIAS, Raphael M.; GERAGE, Aline; CUCATO, Gabriel G.; CONCEICAO, Raquel; SANTOS, Raul- Acute Cardiovascular Responses to Self-selected Intensity Exercise in Parkinson's Disease (vol 43, pg 177, 2021)(2022) KANEGUSUKU, Helcio; CUCATO, Gabriel Grizzo; LONGANO, Paulo; OKAMOTO, Erika; PIEMONTE, Maria Elisa Pimentel; CORREIA, Marilia Almeida; RITTI-DIAS, Raphael Mendes
- Reproducibility of Anaerobic and Pain Thresholds in Male Patients With Intermittent Claudication(2016) CHEHUEN, Marcel da Rocha; CUCATO, Gabriel Grizzo; SAES, Glauco Fernandes; COSTA, Luiz Augusto Riani; LEICHT, Anthony Scott; RITTI-DIAS, Raphael Mendes; WOLOSKER, Nelson; FORJAZ, Claudia Lucia de MoraesPURPOSE: Maximal and submaximal parameters assessed during treadmill tests are used to prescribe exercise training and assess exercise-induced adaptations in patients with intermittent claudication (IC). Although reproducibility of maximal parameters is well documented, the reproducibility of submaximal is not clear. The aim of this study was to identify the reproducibility (reliability and agreement) of heart rate (HR) and oxygen uptake (o(2)) measured at the anaerobic (AT) and the pain (PT) thresholds assessed during a maximal test in patients with IC. METHODS: Twenty male patients with IC underwent 2 cardiopulmonary treadmill tests to maximal pain. The HR ando(2) at the AT and PT were identified, and differences between repeat tests were compared. Reliability was determined by intraclass coefficient correlation (ICC). Agreement was assessed by coefficient of variation (CV), standard error of measurement (SEM), smallest detectable difference (SDD), and limits of agreement (LOA). RESULTS: The o(2) at AT and PT exhibited moderate reliability and moderate/good agreement (ICC = 0.73 and 0.70; CV = 9.6% and 11.1%, respectively). The HR at the AT and PT exhibited high reliability and good agreement (ICC = 0.87 and 0.92; SEM = 3.9 and 3.2 bpm; SDD = 10.8 and 8.8 bpm, respectively). The LOA for o(2) at AT and PT were 20% and for HR 11 bpm. CONCLUSIONS: The o(2) and HR measured at the AT and PT were moderately to highly reproducible in male patients with IC. The HR and o(2) at AT and PT may be used to establish training intensity and evaluate training effectiveness for these patients in clinical practice and research.
- Graduated Compression Stockings Does Not Decrease Walking Capacity and Muscle Oxygen Saturation during 6-Minute Walk Test in Intermittent Claudication Patients(2017) CAVALCANTE, Bruno Remigio; RITTI-DIAS, Raphael Mendes; SOARES, Antonio Henrique Germano; DOMINGUES, Wagner Jorge Ribeiro; SAES, Glauco Fernandes; DUARTE, Flavio Henrique; CRUZ, Aline de Paula da; WOLOSKER, Nelson; PUECH-LEAO, Pedro; CUCATO, Gabriel Grizzo; ZERATI, Antonio EduardoBackground: We analyze the effects of graduated compression stoking (GCS) on walking capacity and oxygen saturation in intermittent claudication (IC) patients. Methods: Eighteen patients with IC performed the 6-minute walking test in 2 conditions in random order: GCS or placebo sock. Onset claudication distance and total walking distance were obtained. The calf muscle oxygen saturation was continuously monitored before, during, and after 6-minute walk test. Comparisons of the walking capacity and StO(2) parameters between GCS and placebo conditions were analyzed by Wilcoxon rank-sum test. Results: The onset claudication distance (GCS: 120 +/- 99 meters vs. placebo: 150 +/- 126 meters; P= 0.798) and total walking distance (GCS: 330 +/- 108 meters vs. placebo: 324 +/- 60 meters; P= 0.130) were similar between conditions. There were no differences in StO(2) parameters between conditions (P > 0.05). Conclusions: GCS does not decrease walking performance and calf muscle oxygenation saturation during 6-minute walk test in patients with IC.
- Physical activity levels and hepatic steatosis: A longitudinal follow-up study in adults(2018) GERAGE, Aline Mendes; RITTI-DIAS, Raphael Mendes; BALAGOPAL, P. Babu; CONCEICAO, Raquel Dilguerian de Oliveira; UMPIERRE, Daniel; SANTOS, Raul D.; CUCATO, Gabriel Grizzo; BITTENCOURT, Marcio SommerBackground and AimThis study aimed to evaluate the impact of physical activity (PA) on the course of hepatic steatosis (HS) in adults. MethodsHepatic steatosis status (ultrasonography) and PA levels were evaluated in 5860 subjects at baseline and after approximately 2.5years (range: 19-50months). At follow up, possible exposures to different PA levels were those who remained inactive, became inactive, became active, and remained active. After follow up, subjects were then classified according to the four possible states (outcomes): remained without HS, developed HS (subjects without HS at baseline), remained with HS, or reverted HS. ResultsAfter multivariate adjustments, individuals without HS that became or remained physically active were less likely to develop HS compared with those who remained physically inactive (odds ratio=0.75, P=0.04 and 0.75, P=0.03, respectively). Among those with HS at baseline, becoming and remaining physically active beneficially improved the HS status (odds ratio=0.64, P=0.01 and 0.66, P=0.01, respectively). However, the significance was lost when adjusted for changes in body mass index. ConclusionHigher levels of PA were associated with prevention and treatment of HS, with evidence of effect mediation by changes in body mass index.
- Influence of peripheral arterial disease on daily living activities in elderly women(2016) CUCATO, Gabriel Grizzo; RITTI-DIAS, Raphael Mendes; FRANCO, Fabio Gazelato de Mello; MATTOS, Luciana Diniz Nagem Janot de; CENDOROGLO, Maysa Seabra; WOLOSKER, Nelson; NASRI, Fabio; COSTA, Maria Luiza Monteiro; CARVALHO, Jose Antonio Maluf deAging has been associated with decreases in physical and cognitive functions. Peripheral artery disease (PAD) has been associated with further impairments in these functions, especially in women. However, no detailed information is available indicating whether PAD leads to further impairment in these functions in elderly women. Thus, the aims of this study were 1) to compare the capacity to perform daily living activities between elderly women with and without PAD and 2) to identify the factors related with the performance in daily activities. Twenty-seven elderly women with PAD and 22 elderly non-PAD women were surveyed in a geriatric hospital. Women aged >= 65 years and with no signal of dementia were included. PAD was identified by the ankle-brachial index <= 0.90, whereas elderly non-PAD women presented ankle-brachial index >1.0. Patients were interviewed to obtain information regarding basic (Katz questionnaire) and instrumental daily living activities (Lawton-Brody scale) and performed the mini-mental state examination, handgrip strength test, and timed up and go tests. PAD and non-PAD women had similar age, clinical characteristics, handgrip strength test, and cognitive function (P > 0.05). The capacity to perform basic and instrumental daily living activities was similar between PAD and non-PAD women (P > 0.05). In PAD and non-PAD, the instrumental daily living activities were significantly correlated with cognitive function (r = 0.44, P < 0.05 and r = 0.74 and P < 0.05, respectively). PAD elderly women present similar capacity to perform basic and instrumental daily activities than non-PAD women. In addition, in both groups, the capacity to perform instrumental daily activities was related with cognitive function.
- Cross-sectional, school-based study of 14-19 year olds showed that raised blood pressure was associated with obesity and abdominal obesity(2017) NASCIMENTO-FERREIRA, Marcus Vinicius; MORAES, Augusto Cesar Ferreira De; RENDO-URTEAGA, Tara; FORKERT, Elsie Costa de Oliveira; COLLESE, Tatiana Sadalla; CUCATO, Gabriel Grizzo; REIS, Victor M. M.; TORRES-LEAL, Francisco Leonardo; MORENO, Luis A.; CARVALHO, Heraclito BarbosaAim: Gaining weight has been directly associated with an increased probability of developing high blood pressure (HBP) and metabolic abnormalities. We examined the independent and combined effects of overweight, obesity and abdominal obesity on blood pressure in adolescents. Methods: This cross-sectional school-based study evaluated 869 adolescents (53.4% girls) from 14 to 19 years of age, and the data were collected in 2013 in the city of Imperatriz, Maranhao, Brazil. The outcome was HBP. The independent variables were overweight and obesity classified by body mass index, abdominal obesity classified by the waist-to-height ratio and the combination of obesity and overweight and abdominal obesity. The potential confounding variables were age, the socio-economic status of the family, parental education, type of school and physical activity levels. Results: The prevalence ratios of HBP were higher when male and female adolescents were overweight (1.61-3.11), generally obese (3.20-4.70), had abdominal obesity (2.18-3.02) and were both generally obese and had abdominal obesity (3.28-5.16) compared with normal weight adolescents. Conclusion: Obesity or abdominal obesity increased the risk of HBP in adolescents aged 14-19. However, adolescents who were both generally obese and had abdominal obesity showed an even higher risk of having HBP.
- Impact of obesity on walking capacity and cardiovascular parameters in patients with peripheral artery disease: A cross-sectional study(2020) KANEGUSUKU, Helcio; CUCATO, Gabriel G.; DOMICIANO, Romulo M.; LONGANO, Paulo; PUECH-LEAO, Pedro; WOLOSKER, Nelson; RITTI-DIAS, Raphael M.; CORREIA, Marilia A.Background: Patients with peripheral artery disease (PAD) present a high prevalence of obesity and metabolic syndrome, as well as diseases related to cardiovascular dysfunction. However, whether obesity influences walking capacity and cardiovascular function in patients with PAD is poorly understood. Objectives: The objective of this study was to analyze the impact of obesity on walking capacity and cardiovascular parameters in patients with PAD. Design: This is a cross-sectional study. Setting: Patients were recruited from public hospitals of Sao Paulo. Methods: One-hundred two patients with PAD and symptoms of intermittent claudication were recruited and divided into 2 groups according to their body mass index: normal weight (<25 kg/m(2)) and overweight/obese ($25 kg/m(2)). Patients were submitted to objective (6-minute walk test) and subjective measurements of walking capacity (Walking Impairment Questionnaire). In addition, cardiovascular parameters (office blood pressure, resting heart rate, arterial stiffness, vascular function, and heart rate variability) were obtained. Results: The speed domain of the Walking Impairment Questionnaire was lower in the overweight/obese group compared to the normal weight group (32 +/- 20 vs 21 +/- 16, respectively, P < .01). Resting heart rate was higher in overweight/obese patients (61 +/- 10 vs 70 +/- 12, respectively, P < .01). However, no other walking capacity or cardiovascular parameter variables were related to obesity in patients with PAD. Conclusion: Obesity influences resting heart rate and walking speed in patients with PAD.
- Symptoms of anxiety and depression and their relationship with barriers to physical activity in patients with intermittent claudication(2021) RAGAZZO, Luciana; PUECH-LEAO, Pedro; WOLOSKER, Nelson; LUCCIA, Nelson de; SAES, Glauco; RITTI-DIAS, Raphael M.; CUCATO, Gabriel Grizzo; KAMIKAVA, Debora Yumi Ferreira; ZERATI, Antonio EduardoOBJECTIVES: Although the practice of physical exercise in patients with intermittent claudication (IC) is often encouraged, adherence is low. The difficulty in performing physical training may be related to the psychological characteristics of patients with claudication. To verify the association between anxiety and depression symptoms and barriers to physical exercise and walking capacity in patients with IC. METHODS: One-hundred and thirteen patients with a clinical diagnosis of IC were included in the study. Patients underwent clinical evaluation by a vascular surgeon, answered the Beck Depression Inventory, and Beck Anxiety Inventory tests were applied by the psychologist. The patients performed the 6-minute test and reported their barriers to physical activity practice in a questionnaire. RESULTS: Patients with signs of depression had a shorter pain-free walking distance (p=0.015) and total walking distance (p=0.035) compared to patients with no signs of depression. Pain-free walking distance (p=0.29) and total walking distance (p=0.07) were similar between patients with and without signs of anxiety. Patients with symptoms of moderate to severe depression reported more barriers to physical activity practice compared to patients without signs of depression. CONCLUSION: Symptoms of anxiety and depression are prevalent among patients with peripheral arterial occlusive disease (PAD). Depression symptoms are associated with personal barriers to exercise, while anxiety symptoms are not. The main barriers to physical activity among patients with IC are exercise-induced pain and the presence of other diseases.