LEONARDO JORGE CORDEIRO DE PAULA

Índice h a partir de 2011
2
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina - Médico

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Agora exibindo 1 - 10 de 28
  • bookPart
    Bradicardias
    (2015) BORGES, Luciana Fatureto; PAULA, Leonardo Jorge Cordeiro de
  • bookPart
    Medicações utilizadas no tratamento de arritmias na emergência
    (2015) NEVES, Carolina Frezzatti de Andrade; PAULA, Leonardo Jorge Cordeiro de; RAMIRES, José Antônio Franchini
  • bookPart
    Complicações mecânicas pós-infarto agudo do miocárdio
    (2018) PAULA, Leonardo Jorge Cordeiro de; GOLDSTEIN, Priscila Gherardi; GAIOTTO, Fábio Antônio
  • bookPart
    Cateterismo cardíaco
    (2015) PAULA, Leonardo Jorge Cordeiro de; PAULA, Caroline Ferraz de; LEMOS NETO, Pedro Alves
  • article 1 Citação(ões) na Scopus
    Protective or Inhibitory Effect of Pharmacological Therapy on Cardiac Ischemic Preconditioning: A Literature Review
    (2022) PAULA, Leonardo Jorge Cordeiro de; UCHIDA, Augusto Hiroshi; REZENDE, Paulo Cury; SOARES, Paulo; SCUDELER, Thiago Luis
    Ischemic preconditioning (IP) is an innate phenomenon, triggered by brief, non-lethal cycles of ischemia/reperfusion applied to a tissue or organ that confers tolerance to a subsequent more prolonged ischemic event. Once started, it can reduce the severity of myocardial ischemia associated with some clinical situations, such as percutaneous coronary intervention (PCI) and intermittent aortic clamping during coronary artery bypass graft surgery (CABG). Although the mechanisms underlying IP have not been completely elucidated, several studies have shown that this phenomenon involves the participation of cell triggers, intracellular signaling pathways, and end-effectors. Understanding this mechanism enables the development of preconditioning mimetic agents. It is known that a range of medications that activate the signaling cascades at different cellular levels can interfere with both the stimulation and the blockade of IP. Investigations of signaling pathways underlying ischemic conditioning have identified a number of therapeutic targets for pharmacological manipulation. This review aims to present and discuss the effects of several medications on myocardial IP.
  • bookPart
    Manejo da anticoagulação em pacientes com valvopatias
    (2018) SILVESTRE, Odilson Marcos; PAULA, Leonardo Jorge Cordeiro de; ABUD, Isabela Cristina Kirnew
  • bookPart
    Bradicardias
    (2018) BORGES, Luciana Fatureto; PAULA, Leonardo Jorge Cordeiro de; ROCHA, Cynthia Aparecida da Silva
  • bookPart
    A abordagem do paciente com dor torácica
    (2016) SOEIRO, Alexandre de Matos; PAULA, Leonardo Jorge Cordeiro; GAIOTTO, Fábio Antônio; OLIVEIRA JR., Múcio Tavares de
  • bookPart
    Medicações utilizadas no tratamento de arritmias na emergência
    (2015) NEVES, Carolina Frezzatti de Andrade; PAULA, Leonardo Jorge Cordeiro de; RAMIRES, José Antônio Franchini
  • article
    Telecardiology guideline in Patient Care with Acute Coronary Syndrome and Other Respiratory Diseases
    (2015) OLIVEIRA JUNIOR, Mucio Tavares de; CANESIN, Manoel Fernandes; MARCOLINO, Milena Soriano; RIBEIRO, Antonio Luiz Pinho; CARVALHO, Antonio Carlos de Camargo; REDDY, Shankar; SANTOS, Adson Roberto Franca dos; FERNANDES, Alfredo Manoel da Silva; AMARAL, Amaury Zatorre; REZENDE, Ana Carolina de; NECHAR JUNIOR, Antonio; NASCIMENTO, Bruno Ramos do; PASTORE, Carlos Alberto; WEN, Chao Lung; GUALANDRO, Danielle Menosi; NAPOLI, Domingos Guilherme; FRANCA, Francisco Faustino A. C.; FEITOSA-FILHO, Gilson Soares; SAAD, Jamil Abdalla; PILLI, Jeanne; PAULA, Leonardo Jorge Cordeiro de; LODI-JUNQUEIRA, Lucas; CESAR, Luis Antonio Machado; BODANESE, Luiz Carlos; GUTIERREZ, Marco Antonio; ALKMIM, Maria Beatriz Moreira; NUNES, Mauricio Batista; MEDEIROS, Orlando Otavio de; MORENO, Ramon Alfredo; GUNDIM, Rosangela Simoes; MONTENEGRO, Sergio Tavares; NAZIMA, Willyan Issamu