ROBERTA SHCOLNIK SZOR
Projetos de Pesquisa
Unidades Organizacionais
16 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 16
- Increased Risk of for Cytomegalovirus Reactivation after Allogeneic HSCT in T-Cell Depleted Patients(2020) MOLLA, Vinicius Campos; AZEVEDO, Roberta; RAMOS, Jessica Fernandes; PONCIANO, Danilo Belchior; MORAES, Pedro Henrique Arruda de; FONSECA, Ana Rita Da; SEIWALD, Maria Cristina Nunez; SERPA, Mariana; FERREIRA, Aliana Meneses; SZOR, Roberta Shcolnik; LEONEL, Rayana Bomfim; XAVIER, Erick Menezes; ROCHA, Vanderson; TUCUNDUVA, Luciana; NOVIS, Yana; NUCCI, Marcio; KALLAS, Esper; ARRAIS, Celso
conferenceObject Surveillance Functional Imaging Has Limited Role in Solitary Plasmacytomas: International Multi-Centre Study of Clinical Outcomes(2017) SHARPLEY, Faye A.; NEFFA, Pedro; PANITSAS, Fotis; KOTHARI, Jaimal; CUTTER, David; SZOR, Roberta Shcolnik; SUBESINGHE, Manil; MARTINEZ, Gracia; ROCHA, Vanderson; RAMASAMY, Karthik- Challenges in Diagnosis and Treatment of Systemic Amyloidosis: 10 Years of Experience in a Public Brazilian University Center(2020) SZOR, Roberta Shcolnik; FERNANDES, Fabio; SEGURO, Fernanda S.; LINO, Angelina M.; JORGE, Lecticia B.; MENDONCA, Leonardo O.; FEITOSA, Valkercyo A.; CASTELLI, Jussara B.; REGO, Eduardo M.; JACOMASSI, Mayara; ALVES, Lucas B. O.; MARTINEZ, Gracia; ROCHA, Vanderson
conferenceObject Treating multiple myeloma in a resource-limited setting: real-world outcomes(2022) MATINEZ, Gracia; SEGURO, Fernanda; JACOMASSI, Mayara; VISNADI, Helena; ATANAZIO, Marcelo; SZOR, Roberta; NEFFA, Pedro; PEREIRA, Thales; SILVA, Wellington; DORLHIAC, Pedro; VELASQUES, Rodrigo; BASSOLI, Lucas; ROCHA, Vanderson- Systemic amyloidosis journey from diagnosis to outcomes: a twelve-year real-world experience of a single center in a middle-income country(2022) SZOR, Roberta Shcolnik; FERNANDES, Fabio; LINO, Angelina Maria Martins; MENDONCA, Leonardo Oliveira; SEGURO, Fernanda Salles; FEITOSA, Valkercyo Araujo; CASTELLI, Jussara Bianchi; JORGE, Lecticia Barbosa; ALVES, Lucas Bassolli de Oliveira; NEVES, Precil Diego Miranda de Menezes; SOUZA, Evandro de Oliveira; CAVALCANTE, Livia Barreira; MALHEIROS, Denise; KALIL, Jorge; MARTINEZ, Gracia Aparecida; ROCHA, VandersonBackground: Systemic amyloidosis is caused by the deposition of misfolded protein aggregates in tissues, leading to progressive organ dysfunction and death. Epidemiological studies originate predominantly from high-income countries, with few data from Latin America. Due to the non-specific clinical manifestations, diagnosing amyloidosis is often challenging and patients experience a long journey and delay in diagnosis. This study aimed to assess clinical and laboratory characteristics, the diagnostic journey, and outcomes of patients with biopsy-proven systemic amyloidosis diagnosed between 2009 and 2020 at a university referral center in a middle-income Latin American country. Patients' medical records were retrospectively reviewed. Results: One hundred and forty-three patients were included. The median age at diagnosis was 60 years and 54% were male. Until the diagnosis, most of the patients (52%) were seen by at least 3 specialists, the main ones being: general practitioners (57%), nephrologists (45%), and cardiologists (38%). The most common manifestations were renal (54%) and cardiac (41%) disorders, and cachexia was seen in 36% of patients. In 72% of the cases, & GE; 2 biopsies were required until the final diagnosis. The median time from symptoms onset to diagnosis was 10.9 months, and most patients (75%) had & GE; 2 organs involved. The following subtypes were identified: AL (68%), ATTR (13%), AA (8%), AFib (4%), and inconclusive (7%). Median OS was 74.3 months in the non-AL subgroup and 18.5 months in AL. Among AL patients, those with advanced cardiac stage had the worst outcome [median OS 8.6 months versus 52.3 for stage III versus I-II, respectively (p < 0.001)]. AL subtype, cardiac involvement, and ECOG & GE; 2 were identified as independent risk factors for reduced survival. Conclusions: Systemic amyloidosis is still an underdiagnosed condition and the delay in its recognition leads to poor outcomes. Medical education, better diagnostic tools, improvement in access to therapies, and establishment of referral centers may improve patient outcomes in middle-income countries.
- Position Statement on Diagnosis and Treatment of Cardiac Amyloidosis-2021(2021) V, Marcus Simoes; FERNANDES, Fabio; MARCONDES-BRAGA, Fabiana G.; SCHEINBERG, Philip; CORREIA, Edileide de Barros; ROHDE, Luis Eduardo P.; BACAL, Fernando; ALVES, Silvia Marinho Martins; MANGINI, Sandrigo; BIOLO, Andreia; BECK-DA-SILVA, Luis; SZOR, Roberta Shcolnik; MARQUES JUNIOR, Wilson; OLIVEIRA, Acary Souza Bulle; CRUZ, Marcia Waddington; BUENO, Bruno Vaz Kerges; HAJJAR, Ludhmila Abrahao; ISSA, Aurora Felice Castro; RAMIRES, Felix Jose Alvarez; COELHO FILHO, Otavio Rizzi; SCHMIDT, Andre; PINTO, Ibraim Masciarelli Francisco; ROCHITTE, Carlos Eduardo; VIEIRA, Marcelo Luiz Campos; MESQUITA, Claudio Tinoco; RAMOS, Celso Dario; SOARES-JUNIOR, Jose; ROMANO, Minna Moreira Dias; MATHIAS JUNIOR, Wilson; GARCIA, Marcelo Iorio; MONTERA, Marcelo Westerlund; MELO, Marcelo Dantas Tavares de; SILVA, Sandra Marques E; GARIBALDI, Pedro Manoel Marques; ALENCAR, Aristoteles Comte de; LOPES, Renato Delascio; AVILA, Diane Xavier de; VIANA, Denizar; SARAIVA, Jose Francisco Kerr; CANESIN, Manoel Fernandes; OLIVEIRA, Glaucia Maria Moraes de; MESQUITA, Evandro Tinoco
conferenceObject Coronary flow reserve by PET 13N-ammonia in patients with hereditary transthyretin amyloidosis with and without cardiac involvement(2022) ALENCAR NETO, A. C.; CAFEZEIRO, C. R. F.; BUENO, B. V. K.; SOUZA, F. Ribeiro De; RISSATO, J. H. S. Henrique; BORGES, T. Souza; CARVALHAL, S. Freitas; LIMA, M. Santos; BUCHPIGUEL, C. Alberto; CHALELA, W. Azem; RAMIRES, F. J. Alvarez; SZOR, R. Shcolnik; KALIL FILHO, R.; ROCHITTE, C. E.; FERNANDES, F.- Amyloid Cardiomyopathy Establishing a Patient Referral Center in Brazil(2021) SZOR, Roberta Shcolnik; ALENCAR, Aristoteles; BUENO, Bruno Vaz Kerges; CAFEZEIRO, Caio Reboucas Fonseca; ALVES, Lucas Bassolli de Oliveira; HAJJAR, Ludhmila Abrahao; MARTINEZ, Gracia Aparecida; ROCHA, Vanderson; FERNANDES, Fabio
- Would Be Cyclophosphamide, Thalidomide and Dexamethasone (CTD) a Possible Treatment For Multiple Myeloma Where Is Not Possible New Drugs?(2013) BELLESSO, Marcelo; SILVA, Marcela Cavalcante de Andrade; VELASQUES, Rodrigo Dolphini; VISNADI, Helena; SHCOLNIK, Roberta; SEGURO, Fernanda Salles; LEVY, Debora; ABDO, Andre Neder Ramires; SANTUCCI, Rodrigo; PEREIRA, Juliana; MARTINEZ, Gracia Aparecida
conferenceObject Gemcitabine-Induced Non-Cardiogenic Pulmonary Edema(2022) SAAVEDRA, N. Medina; BRIDI, G. D.; SANTOS, G. C.; MARANGONI, K. F.; NASCIMENTO, Y. P. P.; SCIORTINO, A. D.; VISNADI, H.; SZOR, R. S.; CURY-MARTINS, J.; KAWASSAKI, A. M.