JULIANA FERNANDA CANHADAS BELLI MARIN

(Fonte: Lattes)
Índice h a partir de 2011
3
Lattes
Projetos de Pesquisa
Unidades Organizacionais
LIM/11 - Laboratório de Cirurgia Cardiovascular e Fisiopatologia da Circulação, Hospital das Clínicas, Faculdade de Medicina

Filtros

Limpar filtros

Configurações

Resultados de Busca

Agora exibindo 1 - 6 de 6
  • conferenceObject
    Impact of optimizing of heart failure therapy in cardiac remodeling reversal: morphological, electrical and functional analysis
    (2013) SAMUEL, M. Avila; AYUB-FERREIRA, S. M.; ISSA, V. S.; VIEIRA, M. L. C.; GUIMARAES, G. V.; BELLI, J. F. C.; PEREIRA, M. B.; VALETTE, T. N.; BOCCHI, E. A.
  • conferenceObject
    Treadmill versus cycle ergometer cardiopulmonary exercise testing in patients with chronic heart failure in the beta-blocker era
    (2013) MORITA, M.; BACAL, F.; CASTRO, R. E.; CRUZ, L.; BELLI, J. F. C.; ROQUE, J.; TEIXEIRA-NETO, I. S.; CHIZZOLA, P.; BOCCHI, E. A.; GUIMARAES, G. V.
  • article 3 Citação(ões) na Scopus
    Effects of ss-blocker therapy on exercise oscillatory ventilation in reduced ejection fraction heart failure patients: A case series study
    (2022) BELLI-MARIN, Juliana Fernanda Calhado; BOCCHI, Edimar Alcides; AYUB-FERREIRA, Silvia; CARVAS JUNIOR, Nelson; GUIMARAES, Guilherme Veiga
    Background: Exercise oscillatory ventilation (EOV) is an abnormal breathing pattern that occurs in similar to 20% of patients with heart failure (HF) and is associated with poor prognosis and exercise intolerance. ss-blockers (ss b) are prescribed for most HF patients; however, their effect on EOV remains unclear. We evaluated the effect of ss b on EOV in HF patients with reduced ejection fraction (HFrEF). Methods: Fifteen patients diagnosed with HF, ejection fraction < 45%, aged from 18 to 65 years, were included before starting ss b therapy. Patients underwent clinical evaluation, cardiopulmonary exercise testing, echocardiography, laboratory exams (norepinephrine levels, B type natriuretic peptide) at baseline and after ss b therapy optimized for six months. Presence of exercise oscillatory breathing was determined by two experienced observers who were blinded to the moment of the test (pre or post). Results: Fifteen patients (1 female), aged 49.5 +/- 2.5 years, with HFrEF, NYHA I-III enrolled in the study. The etiologies of the HFrEF were idiopathic (n = 8) and hypertensive (n = 7). LVEF increased after ss b therapy from 25.9 +/- 2.5% to 33 +/- 2.6%, P = 0.02; peak VO2 did not significantly change (21.8 +/- 1.7 vs 24.7 +/- 1.9, P = 0.4); VE/VCO2 slope changed from 32.1 +/- 10.6-27.5 +/- 9.1, P = 0.03. Before ss b initiation, nine patients (60%) had EOV, but only two (13%) did after optimized therapy. McNemar test was used to evaluate the significance of the association between the two moments (P = 0.02). Conclusion: In patients with HF, medical therapy with ss b can reverse EOV. This may explain why these patients experience symptom improvement after ss b therapy.
  • conferenceObject
    Correlation between physical activity in daily life and cardiopulmonary exercise testing in patients with heart failure
    (2013) MORITA, M.; BACAL, F.; ROQUE, J.; BELLI, J. F. C.; TEIXEIRA-NETO, I. S.; CHIZZOLA, P.; BOCCHI, E. A.; GUIMARAES, G. V.
  • article 19 Citação(ões) na Scopus
    Comportamento do ergorreflexo na insuficiência cardíaca
    (2011) BELLI, Juliana Fernanda Canhadas; BACAL, Fernando; BOCCHI, Edimar Alcides; GUIMARAES, Guilherme Veiga
    A large body of evidence has suggested the existence of a reflex network that becomes hyperactive secondary to musculoskeletal alterations that occur in heart failure (HF) syndrome. Together with sympathoinhibitory cardiovascular reflexes, suppressed in the presence of the syndrome, heart failure can contribute to physical exercise intolerance. The hyperactivation of signals originated from receptors located in skeletal muscles (mechanoreceptors - metaboreceptors) is a recently proposed hypothesis to explain the origin of fatigue and dyspnea symptoms in HF. In HF, other alterations in the reflex control system, which are not mutually exclusive, contribute to dyspnea. The inappropriate stimulation of the arterial baroreceptors, with the consequent lack of inhibition of the muscle metaboreflex and carotid chemoreflex unloading and the increase in the renal vasoconstriction with angiotensin II release can also be considered. Although the functional alterations of the reflexes were used independently to illustrate the sympathetic excitation observed in HF, the interaction between these reflexes under normal and pathological conditions, especially its contribution to the sympathoexcitatory state found in HF, has not been broadly investigated. Therefore, questions about a possible association between the muscle receptors (mechano and metaboreceptors) in the genesis of the ergoreflex exacerbation, observed in HF, remain. Thus, the objective of this review was to integrate the knowledge on the mechano and metaboreflex (ergoreflex) in HF syndrome, as well as to clarify the influence of HF drug therapy on the ergoreflex.
  • article 15 Citação(ões) na Scopus
    Behavior of Central and Peripheral Chemoreflexes in Heart Failure
    (2011) GUIMARAES, Guilherme Veiga; BELLI, Juliana Fernanda Canhadas; BACAL, Fernando; BOCCHI, Edimar Alcides